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01-11-2008 | Review

Receptor imaging of pediatric tumors: clinical practice and new developments

Authors: Heike E. Daldrup-Link, Randall A. Hawkins, Reinhard Meier, Robert E. Goldsby, Dmitri Artemov

Published in: Pediatric Radiology | Issue 11/2008

Abstract

Pediatric cancers often have specific molecular fingerprints making them primary candidates for the development of targeted imaging techniques. Tumor-targeted tracers have the potential to substantially advance the sensitivity and specificity of imaging techniques by improving tumor detection and characterization. This article reviews various approaches to target tumors via specific tumor antigens, tumor cell surface receptors and specific surface receptors of the endothelial cells of the tumor vessels. These new applied molecular imaging techniques are expected to improve our knowledge of the biology of pediatric cancers and, ultimately, to help in the development of tailored diagnoses and therapies, which may ultimately lead to better individual long-term outcomes.

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Title: Receptor imaging of pediatric tumors: clinical practice and new developments
Authors: Heike E. Daldrup-Link
Randall A. Hawkins
Reinhard Meier
Robert E. Goldsby
Dmitri Artemov
Publication date: 01-11-2008
Publisher: Springer-Verlag
Published in: Pediatric Radiology / Issue 11/2008
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-008-0878-x

At a glance: The STEP trials

Springer Medicine

Receptor imaging of pediatric tumors: clinical practice and new developments

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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