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Published in: Pediatric Radiology 8/2007

01-08-2007 | Minisymposium

Diffusion-weighted and diffusion tensor imaging for pediatric musculoskeletal disorders

Authors: John D. MacKenzie, Leonardo Gonzalez, Andrea Hernandez, Kai Ruppert, Diego Jaramillo

Published in: Pediatric Radiology | Issue 8/2007

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Abstract

Diffusion-weighted imaging (DWI) is a powerful tool that has recently been applied to evaluate several pediatric musculoskeletal disorders. DWI probes abnormalities of tissue structure by detecting microscopic changes in water mobility that develop when disease alters the organization of normal tissue. DWI provides tissue characterization at a cellular level beyond what is available with other imaging techniques, and can sometimes identify pathology before gross anatomic alterations manifest. These features of early detection and tissue characterization make DWI particularly appealing for probing diseases that affect the musculoskeletal system. This article focuses on the current and future applications of DWI in the musculoskeletal system, with particular attention paid to pediatric disorders. Although most of the applications are experimental, we have emphasized the current state of knowledge and the main research questions that need to be investigated.
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Metadata
Title
Diffusion-weighted and diffusion tensor imaging for pediatric musculoskeletal disorders
Authors
John D. MacKenzie
Leonardo Gonzalez
Andrea Hernandez
Kai Ruppert
Diego Jaramillo
Publication date
01-08-2007
Publisher
Springer-Verlag
Published in
Pediatric Radiology / Issue 8/2007
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-007-0517-y

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