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Urolithiasis
Published in: Urolithiasis 3/2015

Open Access 01-06-2015 | Letter to the Editor

A single-blind, parallel trial of l-hydroxyproline in healthy adult subjects

Authors: Saori Akiduki, Haruo Ito, Koji Morishita, Ayako Kamimura

Published in: Urolithiasis | Issue 3/2015

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Excerpt

As calcium oxalate is the most common constituent of urinary stones animal model of the urolithiasis has been established by feeding l-hydroxyproline, an endogenous precursor of oxalate. However, the influence of oral l-hydroxyproline on human urinary oxalate excretion has not been clearly demonstrated. We herein report a clinical study examining the influence of daily ingestion of l-hydroxyproline on urinary oxalate levels with a focus on measuring oxalic acid excreted in the urine. …
Literature
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Knight J, Jiang J, Assimos DG, Holmes RP (2006) Hydroxyproline ingestion and urinary oxalate and glycolate excretion. Kidney Int 70(11):1929–1934PubMedCentralPubMed
2.
Knight J, Easter LH, Neiberg R, Assimos DG, Holmes RP (2009) Increased protein intake on controlled oxalate diets does not increase urinary oxalate excretion. Urol Res 3(2):63–68CrossRef
3.
Noori N, Honarkar E, Goldfarb DS, Kalantar-Zadeh K, Taheri M, Shakhssalim N, Parvin M, Basiri A (2014) Urinary lithogenic risk profile in recurrent stone formers with hyperoxaluria: a randomized controlled trial comparing DASH (Dietary Approaches to Stop Hypertension)-style and low oxalate diets. Am J Kidney Dis 63(3):456–463CrossRefPubMed
Metadata
Title
A single-blind, parallel trial of l-hydroxyproline in healthy adult subjects
Authors
Saori Akiduki
Haruo Ito
Koji Morishita
Ayako Kamimura
Publication date
01-06-2015
Publisher
Springer Berlin Heidelberg
Published in
Urolithiasis / Issue 3/2015
Print ISSN: 2194-7228
Electronic ISSN: 2194-7236
DOI
https://doi.org/10.1007/s00240-015-0765-5

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