Skip to main content
Top
Published in: Urolithiasis 4/2009

01-08-2009 | Case Report

Ureteral stones due to systemic mastocytosis: diagnostic and therapeutic characteristics

Authors: Gerhard J. Molderings, Gerold Solleder, Ulrich W. Kolck, Jürgen Homann, Detlev Schröder, Ivar von Kügelgen, Roland Vorreuther

Published in: Urolithiasis | Issue 4/2009

Login to get access

Abstract

Urolithiasis is expected to cause a considerable complication in patients with systemic mastocytosis. The aim of the present report is to demonstrate that due to pathological activation and irritability of mast cells, special features in the diagnostic investigation and therapy of urolithiasis have to be considered in patients with systemic mastocytosis. The clinical presentation, diagnostic investigation and therapeutic procedure of urolithiasis in a patient with systemic mastocytosis are described. Urolithiasis may be a significant complication of systemic mastocytosis. Non-contrast CT is the main tool for diagnosing urolithiasis after a detailed history and clinical exam. Patients with systemic mastocytosis should receive a premedication composed of a glucocorticoid and H1- and H2-histamine receptor antagonists. An increased vulnerability of mucosal tissues is expected in patients with systemic mastocytosis that may limit the options of operative and postoperative therapy. Opioids should be used cautiously for analgesia in patients with systemic mastocytosis.
Literature
3.
go back to reference Molderings GJ, Kolck UW, Scheurlen C et al (2007) Multiple novel alterations in Kit tyrosine kinase in patients with gastrointestinally pronounced systemic mast cell activation disorder. Scand J Gastroenterol 42:1045–1053. doi:10.1080/00365520701245744 PubMedCrossRef Molderings GJ, Kolck UW, Scheurlen C et al (2007) Multiple novel alterations in Kit tyrosine kinase in patients with gastrointestinally pronounced systemic mast cell activation disorder. Scand J Gastroenterol 42:1045–1053. doi:10.​1080/​0036552070124574​4 PubMedCrossRef
5.
go back to reference Manion SP, Wheeler JS (1996) Systemic mastocytosis: a possible aetiology of nephrolithiasis. Br J Urol 78:643–644PubMed Manion SP, Wheeler JS (1996) Systemic mastocytosis: a possible aetiology of nephrolithiasis. Br J Urol 78:643–644PubMed
6.
go back to reference Lanternier F, Cohen-Akenine A, Palmerini F et al (2008) Phenotypic and genotypic characteristics of mastocytosis according to the age of onset. PLoS ONE 3:e1906PubMedCrossRef Lanternier F, Cohen-Akenine A, Palmerini F et al (2008) Phenotypic and genotypic characteristics of mastocytosis according to the age of onset. PLoS ONE 3:e1906PubMedCrossRef
10.
go back to reference Carter MC, Uzzaman A, Scott LM et al (2008) Pediatric mastocytosis: routine anesthetic management for a complex disease. Anesth Analg 107:422–427PubMedCrossRef Carter MC, Uzzaman A, Scott LM et al (2008) Pediatric mastocytosis: routine anesthetic management for a complex disease. Anesth Analg 107:422–427PubMedCrossRef
11.
go back to reference Liccardi G, Lobefalo G, Di Florio E et al (2008) Strategies for the prevention of asthmatic, anaphylactic and anaphylactoid reactions during the administration of anesthetics and/or contrast media. J Investig Allergol Clin Immunol 18:1–11PubMed Liccardi G, Lobefalo G, Di Florio E et al (2008) Strategies for the prevention of asthmatic, anaphylactic and anaphylactoid reactions during the administration of anesthetics and/or contrast media. J Investig Allergol Clin Immunol 18:1–11PubMed
13.
go back to reference Sierakowski R, Finlayson B, Landes RR et al (1978) The frequency of urolithiasis in hospital discharge diagnoses in the United States. Invest Urol 15:438–441PubMed Sierakowski R, Finlayson B, Landes RR et al (1978) The frequency of urolithiasis in hospital discharge diagnoses in the United States. Invest Urol 15:438–441PubMed
14.
go back to reference Hiatt RA, Dales LG, Friedman GD et al (1982) Frequency of urolithiasis in a prepaid medical care program. Am J Epidemiol 115:255–265PubMed Hiatt RA, Dales LG, Friedman GD et al (1982) Frequency of urolithiasis in a prepaid medical care program. Am J Epidemiol 115:255–265PubMed
16.
go back to reference Morse RM, Resnick MI (1991) Ureteral calculi: natural history and treatment in an era of advanced technology. J Urol 145:263–265PubMed Morse RM, Resnick MI (1991) Ureteral calculi: natural history and treatment in an era of advanced technology. J Urol 145:263–265PubMed
18.
go back to reference Li F (2006) Pharmacologically induced histamine release: sorting out hypersensitivity reactions to opioids. Drug Ther Topics 35:13–16 Li F (2006) Pharmacologically induced histamine release: sorting out hypersensitivity reactions to opioids. Drug Ther Topics 35:13–16
Metadata
Title
Ureteral stones due to systemic mastocytosis: diagnostic and therapeutic characteristics
Authors
Gerhard J. Molderings
Gerold Solleder
Ulrich W. Kolck
Jürgen Homann
Detlev Schröder
Ivar von Kügelgen
Roland Vorreuther
Publication date
01-08-2009
Publisher
Springer-Verlag
Published in
Urolithiasis / Issue 4/2009
Print ISSN: 2194-7228
Electronic ISSN: 2194-7236
DOI
https://doi.org/10.1007/s00240-009-0198-0

Other articles of this Issue 4/2009

Urolithiasis 4/2009 Go to the issue