Skip to main content
Top
Published in: European Journal of Plastic Surgery 3/2013

01-03-2013 | Original Paper

Key factors in reducing morbidity following inguinal node dissections

Authors: S. Rimouche, S. Ball, P. Kumar, K. Gajanan, J. V. Muphy, R. Swindell, V. Sangar, M. Lau, V. A. C. Ramani, N. W. Clarke, A. Ahmed, B. Winter-Roach, R. Slade, G. L. Ross

Published in: European Journal of Plastic Surgery | Issue 3/2013

Login to get access

Abstract

Background

Inguinal node dissection is associated with high incidence of post-operative morbidity.

Methods

We conducted a retrospective review of all patients who underwent inguinal node dissection at The Christie Hospital between 2001 and 2008. Two hundred thirty two patients undergoing 247 inguinal node dissection outcomes were assessed with a median follow-up of 29 months (range 5 to 75).

Results

Our overall complication rate was 61 %. Our wound infection rate is 34 % with 10 % wound necrosis, 25 % wound breakdown, 35 % seroma, 23 % lymphoedema and 0.4 % haematoma rate. The overall and individual complication rate, including infection wound breakdown, skin necrosis, seroma formation and lymphoedema, was significantly lower with use of a transverse incision for access compared to using a Lazy S and longitudinal incisions (P < 0.008 and P < 0.0001, respectively). Patients undergoing Sartorius switch had a reduced rate of seroma formation (P = 0.018). The preservation of the long saphenous veins was also associated with a reduction on the overall complication rate (P = 0.007).

Conclusions

Inguinal node dissection postoperative complications are reduced by transverse incision, Sartorius switch and preservation of the long saphenous vein.
Level of Evidence: Level IV, prognostic/risk study.
Literature
1.
go back to reference Rouzier R, Haddad B, Dubenard G, Dubois P, Paniel BJ (2003) Inguinofemoral dissection for carcinoma of the vulva: effect of modifications of extent and technique on morbidity and survival. J Am Coll Surg 1996(3):442–450CrossRef Rouzier R, Haddad B, Dubenard G, Dubois P, Paniel BJ (2003) Inguinofemoral dissection for carcinoma of the vulva: effect of modifications of extent and technique on morbidity and survival. J Am Coll Surg 1996(3):442–450CrossRef
2.
go back to reference Paley J, Johnson PR, Adcock LL et al (1997) The effect of Sartorius transposition on wound morbidity following inguinal–femoral lymphadenectomy. Gynecol Oncol 64:237–241PubMedCrossRef Paley J, Johnson PR, Adcock LL et al (1997) The effect of Sartorius transposition on wound morbidity following inguinal–femoral lymphadenectomy. Gynecol Oncol 64:237–241PubMedCrossRef
3.
go back to reference Spiess PE, Hermandez MS, Pettaway CA (2009) Contemporary lymph node dissection: minimizing complications. World J Urol 27(2):205–212PubMedCrossRef Spiess PE, Hermandez MS, Pettaway CA (2009) Contemporary lymph node dissection: minimizing complications. World J Urol 27(2):205–212PubMedCrossRef
4.
go back to reference Poos HP, Kruijff S, Bastiaannet E, van Ginkel RJ, Hoekstra HJ (2007) Therapeutic groin dissection for melanoma: risk factors for short term morbidity. Eur J Surg Oncol 33(1):102–108CrossRef Poos HP, Kruijff S, Bastiaannet E, van Ginkel RJ, Hoekstra HJ (2007) Therapeutic groin dissection for melanoma: risk factors for short term morbidity. Eur J Surg Oncol 33(1):102–108CrossRef
5.
go back to reference Beitsch P, Balch C (1992) Operative morbidity and risk factor assessment in melanoma patients undergoing inguinal lymph node dissection. Am J Surg 164:462–465PubMedCrossRef Beitsch P, Balch C (1992) Operative morbidity and risk factor assessment in melanoma patients undergoing inguinal lymph node dissection. Am J Surg 164:462–465PubMedCrossRef
6.
go back to reference Dardarian TS, Gray HJ, Morgan MA, Rubin SC, Randall TC (2006) Saphenous vein sparing during inguinal lymphadenectomy to reduce morbidity in patients with vulvar carcinoma. Gynecol Oncol 101:140–142PubMedCrossRef Dardarian TS, Gray HJ, Morgan MA, Rubin SC, Randall TC (2006) Saphenous vein sparing during inguinal lymphadenectomy to reduce morbidity in patients with vulvar carcinoma. Gynecol Oncol 101:140–142PubMedCrossRef
7.
go back to reference Lawton G, Rasque H, Ariyan S (2002) Preservation of muscle fascia to decrease lymphedema after complete axillary and ilioinguinofemoral lymphadenectomy for melanoma. J Am Coll Surg 195:339–351PubMedCrossRef Lawton G, Rasque H, Ariyan S (2002) Preservation of muscle fascia to decrease lymphedema after complete axillary and ilioinguinofemoral lymphadenectomy for melanoma. J Am Coll Surg 195:339–351PubMedCrossRef
8.
go back to reference Erba P, Wettstein R, Rieger UM, Haug M, Pierer G, Kalbermatten DF (2008) A study of the effect of Sartorius transposition on lymph flow after ilioinguinal node dissection. Ann Plast Surg 61(3):310–313PubMedCrossRef Erba P, Wettstein R, Rieger UM, Haug M, Pierer G, Kalbermatten DF (2008) A study of the effect of Sartorius transposition on lymph flow after ilioinguinal node dissection. Ann Plast Surg 61(3):310–313PubMedCrossRef
9.
go back to reference Tonouchi H, Ohmori Y, Kobayashi M et al (2004) Operative morbidity associated with groin dissections. Surg Today 34(5):413–418PubMedCrossRef Tonouchi H, Ohmori Y, Kobayashi M et al (2004) Operative morbidity associated with groin dissections. Surg Today 34(5):413–418PubMedCrossRef
10.
go back to reference Urist MM, Maddox WA, Kennedy JE, Balch CM (1983) Patient risk factors and surgical morbidity after regional lymphadenectomy in 204 melanoma patients. Cancer 51:2152–2156PubMedCrossRef Urist MM, Maddox WA, Kennedy JE, Balch CM (1983) Patient risk factors and surgical morbidity after regional lymphadenectomy in 204 melanoma patients. Cancer 51:2152–2156PubMedCrossRef
11.
go back to reference Serpell JW, Carne PWG, Bailey M (2003) Radical lymph node dissection for melanoma. ANZ J Surg 73:294–299PubMedCrossRef Serpell JW, Carne PWG, Bailey M (2003) Radical lymph node dissection for melanoma. ANZ J Surg 73:294–299PubMedCrossRef
12.
go back to reference Karakousis CP (1998) Therapeutic node dissections in malignant melanoma. Ann Surg Oncol 5:473–482PubMedCrossRef Karakousis CP (1998) Therapeutic node dissections in malignant melanoma. Ann Surg Oncol 5:473–482PubMedCrossRef
13.
go back to reference Shaw JH, Rumball EM (1990) Complications and local recurrence following lymphadenectomy. Br J Surg 77:760–764PubMedCrossRef Shaw JH, Rumball EM (1990) Complications and local recurrence following lymphadenectomy. Br J Surg 77:760–764PubMedCrossRef
14.
go back to reference De Vries M, Vonkeman WG, Van Ginkel RJ, Hoekstra HJ (2006) Morbidity after inguinal sentinel lymph node biopsy and completion lymph node dissection in patients with cutaneous melanoma. Eur J Surg Oncol 32:785–789PubMedCrossRef De Vries M, Vonkeman WG, Van Ginkel RJ, Hoekstra HJ (2006) Morbidity after inguinal sentinel lymph node biopsy and completion lymph node dissection in patients with cutaneous melanoma. Eur J Surg Oncol 32:785–789PubMedCrossRef
15.
go back to reference Baas PC, Schraffordt Koops H, Hoekstra HJ, Oosterhuis JW, Oldhoff J (1992) Groin dissection in the treatment of lower-extremity melanoma. Short-term and long-term morbidity. Arch Surg 127:281–286PubMedCrossRef Baas PC, Schraffordt Koops H, Hoekstra HJ, Oosterhuis JW, Oldhoff J (1992) Groin dissection in the treatment of lower-extremity melanoma. Short-term and long-term morbidity. Arch Surg 127:281–286PubMedCrossRef
16.
17.
go back to reference Hughes TMD, Thomas JM (1999) Combined inguinal and pelvic lymph node dissection for stage II melanoma. Br J Surg 86:1493–1498PubMedCrossRef Hughes TMD, Thomas JM (1999) Combined inguinal and pelvic lymph node dissection for stage II melanoma. Br J Surg 86:1493–1498PubMedCrossRef
18.
go back to reference Van Akkooi ACJ, Bouwhuis MG, Van Geel AN et al (2007) Morbidity and prognosis after therapeutic lymph node dissections for malignant melanoma. Eur J Surg Oncol 33:102–108PubMedCrossRef Van Akkooi ACJ, Bouwhuis MG, Van Geel AN et al (2007) Morbidity and prognosis after therapeutic lymph node dissections for malignant melanoma. Eur J Surg Oncol 33:102–108PubMedCrossRef
19.
go back to reference Hughes TMD, A’Hern RP, Thomas JM (2000) Prognosis and surgical management of patients with palpable inguinal lymph node metastases from melanoma. Br J Surg 87:892–901PubMedCrossRef Hughes TMD, A’Hern RP, Thomas JM (2000) Prognosis and surgical management of patients with palpable inguinal lymph node metastases from melanoma. Br J Surg 87:892–901PubMedCrossRef
20.
go back to reference Judson PL, Jonson AL, Paley PJ et al (2004) A prospective, randomized study analyzing Sartorius transposition following inguinal–femoral lymphadenectomy. Gynecol Oncol 95(1):226–230PubMedCrossRef Judson PL, Jonson AL, Paley PJ et al (2004) A prospective, randomized study analyzing Sartorius transposition following inguinal–femoral lymphadenectomy. Gynecol Oncol 95(1):226–230PubMedCrossRef
21.
go back to reference Karakousis CP, Driscoll DL, Rose B, Walsh DL (1994) Groin dissection in malignant melanoma. Ann Surg Oncol 1(4):271–27PubMedCrossRef Karakousis CP, Driscoll DL, Rose B, Walsh DL (1994) Groin dissection in malignant melanoma. Ann Surg Oncol 1(4):271–27PubMedCrossRef
22.
go back to reference Johnson DE, Lo RK (1984) Complications of groin dissection in penile cancer: experience with 101 lymphadenectomies. Urology 24(4):312–314PubMedCrossRef Johnson DE, Lo RK (1984) Complications of groin dissection in penile cancer: experience with 101 lymphadenectomies. Urology 24(4):312–314PubMedCrossRef
23.
go back to reference Kamat MR, Kulkarni JN, Tongaonkar HB (1993) Carcinoma of the penis: the Indian experience. J Surg Oncol 52:50–55PubMedCrossRef Kamat MR, Kulkarni JN, Tongaonkar HB (1993) Carcinoma of the penis: the Indian experience. J Surg Oncol 52:50–55PubMedCrossRef
24.
go back to reference Lopes A, Hidalgo GS, Kowalski LP, Torlani H, Rossi BM, Fonseca FP (1996) Prognostic factors in carcinoma of the penis: multivariate analysis of 145 patients treated with amputation and lymphadenectomy. J Urol 156:1637–1642PubMedCrossRef Lopes A, Hidalgo GS, Kowalski LP, Torlani H, Rossi BM, Fonseca FP (1996) Prognostic factors in carcinoma of the penis: multivariate analysis of 145 patients treated with amputation and lymphadenectomy. J Urol 156:1637–1642PubMedCrossRef
25.
26.
go back to reference Darai E, Karaitianos I, Durand JC (1988) Treatment of inguinal lymph nodes in cancer of the penis: apropos of 85 cases treated at the Institut Curie. Ann Chir 42:748–752PubMed Darai E, Karaitianos I, Durand JC (1988) Treatment of inguinal lymph nodes in cancer of the penis: apropos of 85 cases treated at the Institut Curie. Ann Chir 42:748–752PubMed
27.
go back to reference Ayyappan K, Ananthakrishnan N, Sankaran V (1994) Can regional lymph node involvement be predicted in patients with carcinoma of the penis? Br J Urol 73:549–553PubMedCrossRef Ayyappan K, Ananthakrishnan N, Sankaran V (1994) Can regional lymph node involvement be predicted in patients with carcinoma of the penis? Br J Urol 73:549–553PubMedCrossRef
28.
go back to reference Bevan-Thomas R, Slaton JW, Pettaway CA (2002) Contemporary morbidity from lymphadenectomy for penile squamous cell carcinoma: the M. D. Anderson Cancer Centre experience. J Urol 167:1638–1642PubMedCrossRef Bevan-Thomas R, Slaton JW, Pettaway CA (2002) Contemporary morbidity from lymphadenectomy for penile squamous cell carcinoma: the M. D. Anderson Cancer Centre experience. J Urol 167:1638–1642PubMedCrossRef
29.
go back to reference Nelson BA, Cookson MS, Smith JAJ, Chang SS (2004) Complications of inguinal and pelvic lymphadenectomy for squamous cell carcinoma of the penis: a contemporary series. J Urol 172:494–497PubMedCrossRef Nelson BA, Cookson MS, Smith JAJ, Chang SS (2004) Complications of inguinal and pelvic lymphadenectomy for squamous cell carcinoma of the penis: a contemporary series. J Urol 172:494–497PubMedCrossRef
30.
go back to reference Swan MC, Furniss D, Cassel OCS (2004) Surgical management of metastatic inguinal lymphadenopathy. BMJ 329(7477):1272–1276PubMedCrossRef Swan MC, Furniss D, Cassel OCS (2004) Surgical management of metastatic inguinal lymphadenopathy. BMJ 329(7477):1272–1276PubMedCrossRef
31.
go back to reference Mortenson MM, Xing Y, Weaver S et al (2008) Fibrin sealant does not decrease seroma output or time to drain removal following inguino-femoral lymph node dissection in melanoma: a randomized controlled trial (CNT 00506311). World J Surg Oncol 6:63PubMedCrossRef Mortenson MM, Xing Y, Weaver S et al (2008) Fibrin sealant does not decrease seroma output or time to drain removal following inguino-femoral lymph node dissection in melanoma: a randomized controlled trial (CNT 00506311). World J Surg Oncol 6:63PubMedCrossRef
Metadata
Title
Key factors in reducing morbidity following inguinal node dissections
Authors
S. Rimouche
S. Ball
P. Kumar
K. Gajanan
J. V. Muphy
R. Swindell
V. Sangar
M. Lau
V. A. C. Ramani
N. W. Clarke
A. Ahmed
B. Winter-Roach
R. Slade
G. L. Ross
Publication date
01-03-2013
Publisher
Springer-Verlag
Published in
European Journal of Plastic Surgery / Issue 3/2013
Print ISSN: 0930-343X
Electronic ISSN: 1435-0130
DOI
https://doi.org/10.1007/s00238-012-0757-4

Other articles of this Issue 3/2013

European Journal of Plastic Surgery 3/2013 Go to the issue