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01-11-2017 | Head-Neck-ENT Radiology

Imaging findings of primary immunoglobulin G4-related cervical lymphadenopathy

Authors: Masaya Kawaguchi, Hiroki Kato, Yusuke Kito, Keisuke Mizuta, Mitsuhiro Aoki, Keizo Kato, Satoshi Goshima, Masayuki Matsuo

Published in: Neuroradiology | Issue 11/2017

Abstract

Purpose

The purpose of the present study was to assess imaging findings of primary immunoglobulin G4 (IgG4)-related cervical lymphadenopathy.

Methods

Five consecutive patients with clinically, serologically, and histopathologically confirmed primary IgG4-related cervical lymphadenopathy without any other organ involvement were included. All patients underwent contrast-enhanced computed tomography (CT), and four underwent ¹⁸F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/CT. We retrospectively reviewed the images and assessed the number, size, location, central necrosis, perinodal infiltration, penetrating vessels, and maximum standardized uptake values (SUVmax) of the enlarged cervical nodes.

Results

Thirteen enlarged cervical nodes measuring larger than 10 mm in minimum diameter were identified. The maximum and minimum diameter of enlarged nodes ranged from 1.2 to 3.2 cm (median, 1.8 cm) and from 1.0 to 1.9 cm (median, 1.2 cm), respectively. Lymphadenopathy was unilateral in all patients, and eight enlarged nodes were located at level IB (62%), one at level II (8%), three at level IV (23%), and one at level V (8%). Central necrosis was not seen in any nodes. Perinodal infiltration was seen in only one node (8%), and penetrating vessels were seen in seven nodes (54%). The median SUVmax of nine nodes was 4.45 (range, 2.08–12.44).

Conclusion

Eight enlarged nodes (62%) were located in the submandibular region. Central necrosis was not observed in any nodes and perinodal infiltration was observed in one node (8%).

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Title: Imaging findings of primary immunoglobulin G4-related cervical lymphadenopathy
Authors: Masaya Kawaguchi
Hiroki Kato
Yusuke Kito
Keisuke Mizuta
Mitsuhiro Aoki
Keizo Kato
Satoshi Goshima
Masayuki Matsuo
Publication date: 01-11-2017
Publisher: Springer Berlin Heidelberg
Published in: Neuroradiology / Issue 11/2017
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-017-1921-0

ACC 2024 Congress

Springer Medicine

Imaging findings of primary immunoglobulin G4-related cervical lymphadenopathy

Abstract

Purpose

Methods

Results

Conclusion

ACC 2024 Congress

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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