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Neuroradiology

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01-02-2016 | Interventional Neuroradiology

Morphological risk factors for the rupture of anterior communicating artery aneurysms: the significance of fenestration

Authors: Jai Ho Choi, Kyung Il Jo, Keon Ha Kim, Pyoung Jeon, Je Young Yeon, Jong Soo Kim, Seung Chyul Hong

Published in: Neuroradiology | Issue 2/2016

Abstract

Introduction

The purpose of this study was to evaluate morphological factors associated with rupture in anterior communicating artery (AcomA) aneurysms and to investigate the significance of AcomA fenestration as a risk factor for aneurysm rupture.

Methods

The clinical and radiologic findings of 255 patients with AcomA aneurysms treated with coil embolization between January 2005 and March 2014 were retrospectively reviewed. We performed univariate and multivariate analyses to evaluate the associations between morphological variables and rupture status.

Results

The number of patients with AcomA fenestration was 17 out of 255 (6.6 %). There were no statistically significant differences between the fenestration group and non-fenestration group in clinical and morphological characteristics. Multivariate logistic regression tests showed that superior direction of aneurysm dome (OR 2.802, p = 0.023), presence of a bleb (OR 5.998, p < 0.001), high aspect ratio (OR 3.138, p = 0.009), size greater than 7 mm (OR 3.356, p = 0.013), and AcomA fenestration (OR 4.135, p = 0.026) were significantly associated with AcomA aneurysm rupture.

Conclusions

The results of this study demonstrated that a fenestrated AcomA is associated with risk of aneurysm rupture. Therefore, AcomA fenestration can be considered as an important morphological risk factor for rupture, along with other known risk factors such as the direction of aneurysm dome, a bleb, high aspect ratio, and size.

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Title: Morphological risk factors for the rupture of anterior communicating artery aneurysms: the significance of fenestration
Authors: Jai Ho Choi
Kyung Il Jo
Keon Ha Kim
Pyoung Jeon
Je Young Yeon
Jong Soo Kim
Seung Chyul Hong
Publication date: 01-02-2016
Publisher: Springer Berlin Heidelberg
Published in: Neuroradiology / Issue 2/2016
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-015-1610-9

At a glance: The STEP trials

Springer Medicine

Morphological risk factors for the rupture of anterior communicating artery aneurysms: the significance of fenestration

Abstract

Introduction

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusions

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