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Neuroradiology
Published in: Neuroradiology 10/2015

01-10-2015 | Invited Review

Bilateral symmetrical basal ganglia and thalamic lesions in children: an update (2015)

Authors: Giulio Zuccoli, Michael Paul Yannes, Raffaele Nardone, Ariel Bailey, Amy Goldstein

Published in: Neuroradiology | Issue 10/2015

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Abstract

Introduction

In children, many inherited or acquired neurological disorders may cause bilateral symmetrical signal intensity alterations in the basal ganglia and thalami.

Methods

A literature review was aimed at assisting neuroradiologists, neurologists, infectious diseases specialists, and pediatricians to provide further understanding into the clinical and neuroimaging features in pediatric patients presenting with bilateral symmetrical basal ganglia and thalamic lesions on magnetic resonance imaging (MRI).

Results

We discuss hypoxic-ischemic, toxic, infectious, immune-mediated, mitochondrial, metabolic, and neurodegenerative disorders affecting the basal ganglia and thalami.

Conclusion

Recognition and correct evaluation of basal ganglia abnormalities, together with a proper neurological examination and laboratory findings, may enable the identification of each of these clinical entities and lead to earlier diagnosis.
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Metadata
Title
Bilateral symmetrical basal ganglia and thalamic lesions in children: an update (2015)
Authors
Giulio Zuccoli
Michael Paul Yannes
Raffaele Nardone
Ariel Bailey
Amy Goldstein
Publication date
01-10-2015
Publisher
Springer Berlin Heidelberg
Published in
Neuroradiology / Issue 10/2015
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI
https://doi.org/10.1007/s00234-015-1568-7

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