Top

Published in:

01-04-2017 | Research Article

Functional near-infrared spectroscopy (fNIRS) brain imaging of multi-sensory integration during computerized dynamic posturography in middle-aged and older adults

Authors: Chia-Cheng Lin, Jeffrey W. Barker, Patrick J. Sparto, Joseph M. Furman, Theodore J. Huppert

Published in: Experimental Brain Research | Issue 4/2017

Abstract

Studies suggest that aging affects the sensory re-weighting process, but the neuroimaging evidence is minimal. Functional Near-Infrared Spectroscopy (fNIRS) is a novel neuroimaging tool that can detect brain activities during dynamic movement condition. In this study, fNIRS was used to investigate the hemodynamic changes in the frontal-lateral, temporal-parietal, and occipital regions of interest (ROIs) during four sensory integration conditions that manipulated visual and somatosensory feedback in 15 middle-aged and 15 older adults. The results showed that the temporal-parietal ROI was activated more when somatosensory and visual information were absent in both groups, which indicated the sole use of vestibular input for maintaining balance. While both older adults and middle-aged adults had greater activity in most brain ROIs during changes in the sensory conditions, the older adults had greater increases in the occipital ROI and frontal–lateral ROIs. These findings suggest a cortical component to sensory re-weighting that is more distributed and requires greater attention in older adults.

Abdelnour AF, Huppert T (2009) Real-time imaging of human brain function by near-infrared spectroscopy using an adaptive general linear model. Neuroimage S1053-8119(09):00081–00087. doi:10.1016/j.neuroimage.2009.01.033

Abdelnour F, Huppert T (2010) A random-effects model for group-level analysis of diffuse optical brain imaging. Biomed. Opt Express 2:1–25. doi:10.1364/BOE.2.000001

Allum JH, Zamani F, Adkin AL, Ernst A (2002) Differences between trunk sway characteristics on a foam support surface and on the Equitest ankle-sway-referenced support surface. Gait Posture 16:264–270CrossRefPubMed

Barker JW, Aarabi A, Huppert TJ (2013) Autoregressive model based algorithm for correcting motion and serially correlated errors in fNIRS. Biomed. Opt Express 4:1366–1379. doi:10.1364/BOE.4.001366189317 CrossRef

Boas DA, Dale AM, Franceschini MA (2004) Diffuse optical imaging of brain activation: approaches to optimizing image sensitivity, resolution, and accuracy. Neuroimage 23(Suppl 1):S275–S288. doi:10.1016/j.neuroimage.2004.07.011 CrossRefPubMed

Cabeza R (2001) Cognitive neuroscience of aging: contributions of functional neuroimaging. Scand J Psychol 42:277–286CrossRefPubMed

Cham R, Perera S, Studenski SA, Bohnen NI (2007) Striatal dopamine denervation and sensory integration for balance in middle-aged and older adults. Gait Posture 26:516–525. doi:10.1016/j.gaitpost.2006.11.204 CrossRefPubMed

Cope M, Delpy DT, Reynolds EO, Wray S, Wyatt J, van der Zee P (1988) Methods of quantitating cerebral near infrared spectroscopy data. Adv Exp Med Biol 222:183–189CrossRefPubMed

Faraldo-Garcia A, Santos-Perez S, Crujeiras-Casais R, Labella-Caballero T, Soto-Varela A (2012) Influence of age and gender in the sensory analysis of balance control. Eur Arch Otorhinolaryngol 269:673–677. doi:10.1007/s00405-011-1707-7 CrossRefPubMed

Holmes CJ et al (1998) Enhancement of MR images using registration for signal averaging. J Comput Assist Tomogr 22:324–333CrossRefPubMed

Holtzer R, Epstein N, Mahoney JR, Izzetoglu M, Blumen HM (2014) Neuroimaging of mobility in aging: a targeted review. J Gerontol A Biol Sci Med Sci 69:1375–1388. doi:10.1093/gerona/glu052 CrossRefPubMedPubMedCentral

Huppert TJ, Hoge RD, Dale AM, Franceschini MA, Boas DA (2006a) Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging. J Biomed Opt 11:064018. doi:10.1117/1.2400910 CrossRefPubMedPubMedCentral

Huppert TJ, Hoge RD, Diamond SG, Franceschini MA, Boas DA (2006b) A temporal comparison of BOLD, ASL, and NIRS hemodynamic responses to motor stimuli in adult humans. Neuroimage 29:368–382. doi:10.1016/j.neuroimage.2005.08.065 CrossRefPubMed

Huppert TJ, Diamond SG, Franceschini MA, Boas DA (2009) HomER: a review of time-series analysis methods for near-infrared spectroscopy of the brain. Appl Opt 48:D280–D298CrossRefPubMedPubMedCentral

Huppert T, Schmidt B, Beluk N, Furman J, Sparto P (2013) Measurement of brain activation during an upright stepping reaction task using functional near-infrared spectroscopy. Hum Brain Mapp 34:2817–2828. doi:10.1002/hbm.22106 CrossRefPubMed

Jongkees LW (1948) Value of the caloric test of the labyrinth. Arch Otolaryngol 48:402–417. doi:10.1001/archotol.1948.00690040414003 CrossRef

Karim H, Schmidt B, Dart D, Beluk N, Huppert T (2012) Functional near-infrared spectroscopy (fNIRS) of brain function during active balancing using a video game system. Gait Posture 35:367–372. doi:10.1016/j.gaitpost.2011.10.007S0966-6362(11)00411-5 CrossRefPubMed

Karim H, Fuhrman SI, Sparto P, Furman J, Huppert T (2013a) Functional brain imaging of multi-sensory vestibular processing during computerized dynamic posturography using near-infrared spectroscopy. Neuroimage 74:318–325. doi:10.1016/j.neuroimage.2013.02.010S1053-8119(13)00137-7 CrossRefPubMedPubMedCentral

Karim HT, Fuhrman SI, Furman JM, Huppert TJ (2013b) Neuroimaging to detect cortical projection of vestibular response to caloric stimulation in young and older adults using functional near-infrared spectroscopy (fNIRS). Neuroimage 76:1–10. doi:10.1016/j.neuroimage.2013.02.061S1053-8119(13)00216-4 CrossRefPubMedPubMedCentral

Laurienti PJ, Burdette JH, Maldjian JA, Wallace MT (2006) Enhanced multisensory integration in older adults. Neurobiol Aging 27:1155–1163. doi:10.1016/j.neurobiolaging.2005.05.024 CrossRefPubMed

Lee DN, Aronson E (1974) Visual proprioceptie control of standing in human infants. Perception Psychophysics 15:529–532CrossRef

Mahboobin A, Loughlin PJ, Redfern MS, Sparto PJ (2005) Sensory re-weighting in human postural control during moving-scene perturbations. Exp Brain Res 167:260–267. doi:10.1007/s00221-005-0053-7 CrossRefPubMed

Mihara M, Miyai I, Hatakenaka M, Kubota K, Sakoda S (2008) Role of the prefrontal cortex in human balance control. Neuroimage 43:329–336. doi:10.1016/j.neuroimage.2008.07.0291053-8119(08)00848-3 CrossRefPubMed

Nashner L, Berthoz A (1978) Visual contribution to rapid motor responses during postural control. Brain Res 150:403–407CrossRefPubMed

Nashner LM, Black FO, Wall C 3rd (1982) Adaptation to altered support and visual conditions during stance: patients with vestibular deficits. J Neurosci 2:536–544PubMed

O’Connor KW, Loughlin PJ, Redfern MS, Sparto PJ (2008) Postural adaptations to repeated optic flow stimulation in older adults. Gait Posture 28:385–391. doi:10.1016/j.gaitpost.2008.01.010 CrossRefPubMedPubMedCentral

Papegaaij S, Taube W, Baudry S, Otten E, Hortobagyi T (2014a) Aging causes a reorganization of cortical and spinal control of posture. Front Aging Neurosci 6:28 doi:10.3389/fnagi.2014.00028 PubMedPubMedCentral

Papegaaij S, Taube W, Hogenhout M, Baudry S, Hortobagyi T (2014b) Age-related decrease in motor cortical inhibition during standing under different sensory conditions. Front Aging Neurosci 6:126 doi:10.3389/fnagi.2014.00126 PubMedPubMedCentral

Peterka RJ (2002) Sensorimotor integration in human postural control. J Neurophysiol 88:1097–1118CrossRefPubMed

Peterka RJ, Loughlin PJ (2004) Dynamic regulation of sensorimotor integration in human postural control. J Neurophysiol 91:410–423. doi:10.1152/jn.00516.2003 CrossRefPubMed

Radel R, Brisswalter J, Perrey S (2016) Saving mental effort to maintain physical effort: a shift of activity within the prefrontal cortex in anticipation of prolonged exercise. Cogn Affect Behav Neurosci. doi:10.3758/s13415-016-0480-x

Taube W, Gruber M, Beck S, Faist M, Gollhofer A, Schubert M (2007) Cortical and spinal adaptations induced by balance training: correlation between stance stability and corticospinal activation. Acta Physiol (Oxf) 189:347–358. doi:10.1111/j.1365-201X.2007.01665.x CrossRef

Tsuzuki D, Dan I (2014) Spatial registration for functional near-infrared spectroscopy: from channel position on the scalp to cortical location in individual and group analyses. Neuroimage 85(Pt 1):92–103CrossRefPubMed

Wai YY, Wang JJ, Weng YH, Lin WY, Ma HK, Ng SH, Wan YL, Wang CH (2012) Cortical involvement in a gait-related imagery task: comparison between Parkinson’s disease and normal aging. Parkinsonism Relat Disord 18:537–542. doi:10.1016/j.parkreldis.2012.02.004 CrossRefPubMed

Whitney SL, Marchetti GF, Schade A, Wrisley DM (2004) The sensitivity and specificity of the Timed “Up & Go” and the Dynamic Gait Index for self-reported falls in persons with vestibular disorders. J Vestib Res 14:397–409PubMed

Woollacott MH, Shumway-Cook A (1990) Changes in posture control across the life span–a systems approach. Phys Ther 70:799–807CrossRefPubMed

Woollacott M, Debu B, Mowatt M (1987) Neuromuscular control of posture in the infant and child: is vision dominant? J Mot Behav 19:167–186CrossRefPubMed

Wrisley DM, Marchetti GF, Kuharsky DK, Whitney SL (2004) Reliability, internal consistency, and validity of data obtained with the functional gait assessment. Phys Ther 84:906–918PubMed

Ye JC, Tak S, Jang KE, Jung J, Jang J (2009) NIRS-SPM: statistical parametric mapping for near-infrared spectroscopy. Neuroimage 44:428–447. doi:10.1016/j.neuroimage.2008.08.036S1053-8119(08)00969-5 CrossRefPubMed

Zwergal A, Linn J, Xiong G, Brandt T, Strupp M, Jahn K (2012) Aging of human supraspinal locomotor and postural control in fMRI. Neurobiol Aging 33:1073–1084. doi:10.1016/j.neurobiolaging.2010.09.022 CrossRefPubMed

Title: Functional near-infrared spectroscopy (fNIRS) brain imaging of multi-sensory integration during computerized dynamic posturography in middle-aged and older adults
Authors: Chia-Cheng Lin
Jeffrey W. Barker
Patrick J. Sparto
Joseph M. Furman
Theodore J. Huppert
Publication date: 01-04-2017
Publisher: Springer Berlin Heidelberg
Published in: Experimental Brain Research / Issue 4/2017
Print ISSN: 0014-4819
Electronic ISSN: 1432-1106
DOI: https://doi.org/10.1007/s00221-017-4893-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Functional near-infrared spectroscopy (fNIRS) brain imaging of multi-sensory integration during computerized dynamic posturography in middle-aged and older adults

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 4/2017

Thirty years of transcranial magnetic stimulation: where do we stand?

Format change and semantic relatedness effects on the ERP correlates of recognition: old pairs, new pairs, different stories

Syncopation affects free body-movement in musical groove

Synaptic contact between median preoptic neurons and subfornical organ neurons projecting to the paraventricular hypothalamic nucleus

Factors influencing planning of a familiar grasp to an object: what it is to pick a cup

Effects of visual feedback and memory on unintentional drifts in performance during finger-pressing tasks