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01-04-2014 | Original Article

Socioeconomic status in relation to incident fracture risk in the Study of Women’s Health Across the Nation

Authors: C. J. Crandall, W. Han, G. A. Greendale, T. Seeman, P. Tepper, R. Thurston, C. Karvonen-Gutierrez, A. S. Karlamangla

Published in: Osteoporosis International | Issue 4/2014

Abstract

Summary

We examined baseline and annual follow-up data (through annual follow-up visit 9) from a cohort of 2,234 women aged 42 to 52 years at baseline. Independent of financial status, higher educational level was associated with lower fracture incidence among non-Caucasian women but not among Caucasian women.

Introduction

This study was conducted to determine the associations of education and income with fracture incidence among midlife women over 9 years of follow-up.

Methods

We examined baseline and annual follow-up data (through annual follow-up visit 9) from 2,234 participants of the Study of Women’s Health Across the Nation, a cohort of women aged 42 to 52 years at baseline. We used Cox proportional hazards regression models to examine the associations of socioeconomic predictors (education, family-adjusted poverty-to-income ratio, and difficulty paying for basics) with time to first incident nontraumatic, nondigital, noncraniofacial fracture.

Results

Independent of family-adjusted poverty-to-income ratio, higher educational level was associated with decreased time to first incident fracture among non-Caucasian women but not among Caucasian women (p _interaction 0.02). Compared with non-Caucasian women who completed no more than high school education, non-Caucasian women who attained at least some postgraduate education had 87 % lower rates of incident nontraumatic fracture (adjusted hazard ratio 0.13, 95 % confidence interval [CI] 0.03–0.60). Among non-Caucasian women, each additional year of education was associated with a 16 % lower odds of nontraumatic fracture (adjusted odds ratio 0.84, 95 % CI 0.73–0.97). Income, family-adjusted poverty-to-income ratio, and degree of difficulty paying for basic needs were not associated with time to first fracture in Caucasian or non-Caucasian women.

Conclusions

Among non-Caucasian midlife women, higher education, but not higher income, was associated with lower fracture incidence. Elucidation of the mechanisms underlying the possible protective effects of higher educational level on nontraumatic fracture incidence may allow us to better target individuals at risk of future fracture.

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Title: Socioeconomic status in relation to incident fracture risk in the Study of Women’s Health Across the Nation
Authors: C. J. Crandall
W. Han
G. A. Greendale
T. Seeman
P. Tepper
R. Thurston
C. Karvonen-Gutierrez
A. S. Karlamangla
Publication date: 01-04-2014
Publisher: Springer London
Published in: Osteoporosis International / Issue 4/2014
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-013-2616-y

At a glance: The STEP trials

Springer Medicine

Socioeconomic status in relation to incident fracture risk in the Study of Women’s Health Across the Nation

Abstract

Summary

Introduction

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Summary

Introduction

Methods

Results

Conclusions

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