Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Osteoporosis International
Published in: Osteoporosis International 3/2012

Open Access 01-03-2012 | Original Article

The rate of hip osteoarthritis in patients with proximal femoral fractures versus hip contusion

Authors: B. Robstad, F. Frihagen, L. Nordsletten

Published in: Osteoporosis International | Issue 3/2012

Login to get access

Abstract

Summary

We found no difference in the rate of radiological hip osteoarthritis in the injured hip when comparing 349 patients with proximal femoral fractures and 112 patients with hip contusion. There was, however, a tendency for more osteoarthritis in patients with trochanteric fractures than in patients with femoral neck fractures.

Introduction

Osteoarthritis (OA) and osteoporotic fractures are two age-related disorders associated with considerable morbidity. There is a clinical impression of an inverse relation between osteoarthritis and osteoporosis, and a protective effect of OA against osteoporotic fractures has been proposed.

Methods

We performed a case–control study in 461 subjects. Cases (n = 349) were patients aged 50 years or above who sustained a proximal femoral fracture from November 2003 to October 2004, registered prospectively in the department’s fracture register. Controls (n = 112) were patients aged 50 years or above with the diagnosis of hip contusion, recruited from the hospital’s discharge register. Radiographic OA was scored according to Kellgren and Lawrence (K&L), and minimal joint space (MJS) was measured in both hips when possible. A K&L grade II or higher or an MJS less than 2.5 mm was defined as OA.

Results

Both in the hip fracture group and in the contusion group mean, the MJS was 3.5 mm on the injured side (p = 0.79). In the fracture group, 31/250 (12%) had MJS <2.5 mm and 16/112 (14%) in the contusion group (p = 0.18). In the fracture group, 40/250 (16%) had a K&L OA grade II or higher, and in the contusion group 20/112 (18%) persons had a K&L OA grade II or higher (p = 0.66). There was a tendency for a higher incidence of OA in patients with trochanteric fractures compared with patients with cervical fractures.

Conclusions

We found no differences on the injured side in the rate of hip OA between hip fracture patients and hip contusion patients.
Literature
1.
Antoniades L, MacGregor AJ, Andrew T, Spector TD (2003) Association of birth weight with osteoporosis and osteoarthritis in adult twins. Rheumatology 42:791–796PubMedCrossRef
2.
Livshits G, Ermakov S, Popham M, Macgregor AJ, Sambrook PN, Spector TD et al (2010) Evidence that bone mineral density plays a role in degenerative disc disease: the UK Twin Spine Study. Ann Rheum Dis 69(12):2102–2106PubMedCrossRef
3.
Cooper C, Eriksson JG, Forsen T, Osmond C, Tuomilehto J, Barker DJ (2001) Maternal height, childhood growth and risk of hip fracture in later life: a longitudinal study. Osteoporos Int 12:623–629PubMedCrossRef
4.
Dequeker J, Goris P, Uytterhoeven R (1983) Osteoporosis and osteoarthritis (osteoarthrosis). Anthropometric distinctions. JAMA 249:1448–1451PubMedCrossRef
5.
Foss MV, Byers PD (1972) Bone density, osteoarthrosis of the hip, and fracture of the upper end of the femur. Ann Rheum Dis 31:259–264PubMedCrossRef
6.
Dretakis EK, Steriopoulos KA, Kontakis GM, Giaourakis G, Economakis G, Dretakis KE (1998) Cervical hip fractures do not occur in arthrotic joints. A clinicoradiographic study of 256 patients. Acta Orthop Scand 69:384–386PubMedCrossRef
7.
Dequeker J, Aerssens J, Luyten FP (2003) Osteoarthritis and osteoporosis: clinical and research evidence of inverse relationship. Aging Clin Exp Res 15:426–439PubMed
8.
Cumming RG, Klineberg RJ (1993) Epidemiological study of the relation between arthritis of the hip and hip fractures. Ann Rheum Dis 52:707–710PubMedCrossRef
9.
Dequeker J, Johnell O (1993) Osteoarthritis protects against femoral neck fracture: the MEDOS study experience. Bone 14(Suppl 1):S51–S56PubMedCrossRef
10.
Verstraeten A, Van EH, Haghebaert G, Nijs J, Geusens P, Dequeker J (1991) Osteoarthrosis retards the development of osteoporosis. Observation of the coexistence of osteoarthrosis and osteoporosis. Clin Orthop Relat Res 264:169–177PubMed
11.
Cooper C, Cook PL, Osmond C, Fisher L, Cawley MI (1991) Osteoarthritis of the hip and osteoporosis of the proximal femur. Ann Rheum Dis 50:540–542PubMedCrossRef
12.
Makinen TJ, Alm JJ, Laine H, Svedstrom E, Aro HT (2007) The incidence of osteopenia and osteoporosis in women with hip osteoarthritis scheduled for cementless total joint replacement. Bone 40:1041–1047PubMedCrossRef
13.
Glowacki J, Hurwitz S, Thornhill TS, Kelly M, Leboff MS (2003) Osteoporosis and vitamin-D deficiency among postmenopausal women with osteoarthritis undergoing total hip arthroplasty. J Bone Joint Surg Am 85-A:2371–2377PubMed
14.
Bettica P, Cline G, Hart DJ, Meyer J, Spector TD (2002) Evidence for increased bone resorption in patients with progressive knee osteoarthritis: longitudinal results from the Chingford study. Arthritis Rheum 46:3178–3184PubMedCrossRef
15.
Wolf O, Strom H, Milbrink J, Larsson S, Mallmin H (2009) Differences in hip bone mineral density may explain the hip fracture pattern in osteoarthritic hips. Acta Orthop 80:308–313PubMedCrossRef
16.
Kellgren JH, Lawrence JS (1957) Radiological assessment of osteoarthrosis. Ann Rheum Dis 16:494–502PubMedCrossRef
17.
Reijman M, Hazes JM, Koes BW, Verhagen AP, Bierma-Zeinstra SM (2004) Validity, reliability, and applicability of seven definitions of hip osteoarthritis used in epidemiological studies: a systematic appraisal. Ann Rheum Dis 63:226–232PubMedCrossRef
18.
Ingvarsson T, Hagglund G, Lindberg H, Lohmander LS (2000) Assessment of primary hip osteoarthritis: comparison of radiographic methods using colon radiographs. Ann Rheum Dis 59:650–653PubMedCrossRef
19.
Ingvarsson T, Hagglund G, Lohmander LS (1999) Prevalence of hip osteoarthritis in Iceland. Ann Rheum Dis 58:201–207PubMedCrossRef
20.
Lanyon P, Muir K, Doherty S, Doherty M (2003) Age and sex differences in hip joint space amongasymptomatic subjects without structural change: implications for epidemiologic studies. Arthritis Rheum 48:1041–1046PubMedCrossRef
21.
Birrell F, Croft P, Cooper C, Hosie G, Macfarlane GJ, Silman A (2000) Radiographic change is common in new presenters in primary care with hip pain. PCR Hip Study Group. Rheumatol (Oxf) 39:772–775CrossRef
22.
Naganathan V, Zochling J, March L, Sambrook PN (2002) Peak bone mass is increased in the hip indaughters of women with osteoarthritis. Bone 30:287–292PubMedCrossRef
23.
Stewart A, Black AJ (2000) Bone mineral density in osteoarthritis. Curr Opin Rheumatol 12:464–467PubMedCrossRef
24.
Meta M, Lu Y, Keyak JH, Lang T (2006) Young-elderly differences in bone density, geometry and strength indices depend on proximal femur sub-region: a cross sectional study in Caucasian-American women. Bone 39:152–158PubMedCrossRef
25.
Lyles KW, Colon-Emeric CS, Magaziner JS, Adachi JD, Pieper CF, Mautalen C et al (2007) Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med 357:1799–1809PubMedCrossRef
Metadata
Title
The rate of hip osteoarthritis in patients with proximal femoral fractures versus hip contusion
Authors
B. Robstad
F. Frihagen
L. Nordsletten
Publication date
01-03-2012
Publisher
Springer-Verlag
Published in
Osteoporosis International / Issue 3/2012
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-011-1628-8

Other articles of this Issue 3/2012

Osteoporosis International 3/2012 Go to the issue

Original Article

Estimation of the lifetime risk of hip fracture for women and men in Canada

Original Article

Premature T cell senescence in Ovx mice is inhibited by repletion of estrogen and medicarpin: a possible mechanism for alleviating bone loss

Original Article

Rib fracture as a predictor of future fractures in young and older postmenopausal women: National Osteoporosis Risk Assessment (NORA)

Original Article

Incidence of hip fracture and prevalence of osteoporosis in Turkey: the FRACTURK study

Original Article

A comparison of case-finding strategies in the UK for the management of hip fractures

Review

Individualizing osteoporosis therapy