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01-12-2008 | Letter

Calculating clinically relevant drug doses to use in animal studies

Authors: R. K. Fuchs, M. R. Allen, K. W. Condon, S. Reinwald, L. M. Miller, D. McClenathan, B. Keck, R. J. Phipps, D. B. Burr

Published in: Osteoporosis International | Issue 12/2008

Excerpt

Dear Editor, …

Fuchs RK, Allen MR, Condon KW, Reinwald S, Miller LM, McClenathan D, Keck B, Phipps RJ, Burr DB (2008) Strontium ranelate does not stimulate bone formation in ovariectomized rats. Osteoporos Int 19:1331–1341 doi:10.1007/s00198-008-0602-6 PubMedCrossRef

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Seeman E (2006) Strontium ranelate: vertebral and non-vertebral fracture risk reduction. Curr Opin Rheumatol 18(Suppl 1):S17–S20PubMedCrossRef

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Marie PJ, Hott M, Modrowski D, De Pollak C, Guillemain J, Deloffre P, Tsouderos Y (1993) An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats. J Bone Miner Res 8(5):607–615PubMedCrossRef

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Title: Calculating clinically relevant drug doses to use in animal studies
Authors: R. K. Fuchs
M. R. Allen
K. W. Condon
S. Reinwald
L. M. Miller
D. McClenathan
B. Keck
R. J. Phipps
D. B. Burr
Publication date: 01-12-2008
Publisher: Springer-Verlag
Published in: Osteoporosis International / Issue 12/2008
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-008-0741-9

At a glance: The STEP trials

Springer Medicine

Calculating clinically relevant drug doses to use in animal studies

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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