Skip to main content
Top
Published in: Osteoporosis International 2/2009

01-02-2009 | Original Article

Serum 25-hydroxyvitamin D and bone mineral density among Hispanic men

Authors: A. B. Araujo, T. G. Travison, G. R. Esche, M. F. Holick, T. C. Chen, J. B. McKinlay

Published in: Osteoporosis International | Issue 2/2009

Login to get access

Abstract

Summary

There are few data on the skeletal health of Hispanic men. We observed differences in vitamin D deficiency and low BMD between Hispanic ethnic subgroups that persisted with adjustment for risk factors. Our data indicate a substantial burden of low BMD and vitamin D deficiency among Hispanic men.

Introduction

Disparities within ethnic groups are generally ignored, but in evolving populations they may have implications for public health. We examined ethnic variation in serum 25-hydroxyvitamin D [25(OH)D] and bone mineral density (BMD) among Hispanic American men.

Methods

Three hundred and fifty-eight Hispanic males 30 to 79 years of age were studied. Logistic regression models assessed variation in odds of vitamin D deficiency (<20 ng/mL) and low BMD (T-score<−1) by ethnicity, with and without adjustment for risk factors (age, smoking, occupation, physical activity, body mass index, and sunlight exposure).

Results

Vitamin D deficiency was most common among Puerto Rican (26%), compared with Dominican (21%), Central American (11%), and South American (9%) men. Percentages with low BMD were: South American (44%), Puerto Rican (34%), Dominican (29%), and Central American (23%). Adjustment for age and risk factors failed to account for Hispanic subgroup differences in vitamin D deficiency and low BMD. Population estimates indicate a substantial burden of low BMD and vitamin D deficiency among Hispanic men.

Conclusions

Our findings underscore the importance of examining the skeletal health of Hispanic subgroups, and suggest that a considerable number of Hispanic men may be at elevated risk of fracture and vitamin D deficiency.
Literature
1.
go back to reference U.S. Department of Health and Human Services (2004) Bone health and osteoporosis: a report of the Surgeon General. U.S. Department of Health and Human Services, Office of the Surgeon General, Rockville, MD U.S. Department of Health and Human Services (2004) Bone health and osteoporosis: a report of the Surgeon General. U.S. Department of Health and Human Services, Office of the Surgeon General, Rockville, MD
2.
go back to reference National Institutes of Health (2001) Osteoporosis prevention, diagnosis, and therapy. National Institutes of Health Consensus Development Conference Statement. Jama 285:785–795CrossRef National Institutes of Health (2001) Osteoporosis prevention, diagnosis, and therapy. National Institutes of Health Consensus Development Conference Statement. Jama 285:785–795CrossRef
3.
go back to reference Heaney RP (1995) Bone mass, the mechanostat, and ethnic differences. J Clin Endocrinol Metab 80:2289–2290PubMedCrossRef Heaney RP (1995) Bone mass, the mechanostat, and ethnic differences. J Clin Endocrinol Metab 80:2289–2290PubMedCrossRef
5.
go back to reference Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A (2007) Incidence and economic burden of osteoporosis-related fractures in the United States, 2005–2025. J Bone Miner Res 22:465–475PubMedCrossRef Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A (2007) Incidence and economic burden of osteoporosis-related fractures in the United States, 2005–2025. J Bone Miner Res 22:465–475PubMedCrossRef
7.
go back to reference Araujo AB, Travison TG, Harris SS, Holick MF, Turner AK, McKinlay JB (2007) Race/ethnic differences in bone mineral density in men. Osteoporos Int 18:943–953PubMedCrossRef Araujo AB, Travison TG, Harris SS, Holick MF, Turner AK, McKinlay JB (2007) Race/ethnic differences in bone mineral density in men. Osteoporos Int 18:943–953PubMedCrossRef
8.
go back to reference Baron JA, Barrett J, Malenka D, Fisher E, Kniffin W, Bubolz T, Tosteson T (1994) Racial differences in fracture risk. Epidemiology 5:42–47PubMedCrossRef Baron JA, Barrett J, Malenka D, Fisher E, Kniffin W, Bubolz T, Tosteson T (1994) Racial differences in fracture risk. Epidemiology 5:42–47PubMedCrossRef
9.
go back to reference Cummings SR, Cauley JA, Palermo L, Ross PD, Wasnich RD, Black D, Faulkner KG (1994) Racial differences in hip axis lengths might explain racial differences in rates of hip fracture. Study of Osteoporotic Fractures Research Group. Osteoporos Int 4:226–229PubMedCrossRef Cummings SR, Cauley JA, Palermo L, Ross PD, Wasnich RD, Black D, Faulkner KG (1994) Racial differences in hip axis lengths might explain racial differences in rates of hip fracture. Study of Osteoporotic Fractures Research Group. Osteoporos Int 4:226–229PubMedCrossRef
10.
go back to reference Dawson-Hughes B (2004) Racial/ethnic considerations in making recommendations for vitamin D for adult and elderly men and women. Am J Clin Nutr 80:1763S–1766SPubMed Dawson-Hughes B (2004) Racial/ethnic considerations in making recommendations for vitamin D for adult and elderly men and women. Am J Clin Nutr 80:1763S–1766SPubMed
11.
go back to reference Farmer ME, White LR, Brody JA, Bailey KR (1984) Race and sex differences in hip fracture incidence. Am J Public Health 74:1374–1380PubMedCrossRef Farmer ME, White LR, Brody JA, Bailey KR (1984) Race and sex differences in hip fracture incidence. Am J Public Health 74:1374–1380PubMedCrossRef
12.
go back to reference George A, Tracy JK, Meyer WA, Flores RH, Wilson PD, Hochberg MC (2003) Racial differences in bone mineral density in older men. J Bone Miner Res 18:2238–2244PubMedCrossRef George A, Tracy JK, Meyer WA, Flores RH, Wilson PD, Hochberg MC (2003) Racial differences in bone mineral density in older men. J Bone Miner Res 18:2238–2244PubMedCrossRef
13.
go back to reference Looker AC, Wahner HW, Dunn WL, Calvo MS, Harris TB, Heyse SP, Johnston CC Jr., Lindsay R (1998) Updated data on proximal femur bone mineral levels of US adults. Osteoporos Int 8:468–489PubMedCrossRef Looker AC, Wahner HW, Dunn WL, Calvo MS, Harris TB, Heyse SP, Johnston CC Jr., Lindsay R (1998) Updated data on proximal femur bone mineral levels of US adults. Osteoporos Int 8:468–489PubMedCrossRef
14.
15.
go back to reference Looker AC, Dawson-Hughes B, Calvo MS, Gunter EW, Sahyoun NR (2002) Serum 25-hydroxyvitamin D status of adolescents and adults in two seasonal subpopulations from NHANES III. Bone 30:771–777PubMedCrossRef Looker AC, Dawson-Hughes B, Calvo MS, Gunter EW, Sahyoun NR (2002) Serum 25-hydroxyvitamin D status of adolescents and adults in two seasonal subpopulations from NHANES III. Bone 30:771–777PubMedCrossRef
16.
go back to reference Tracy JK, Meyer WA, Flores RH, Wilson PD, Hochberg MC (2005) Racial differences in rate of decline in bone mass in older men: the Baltimore men’s osteoporosis study. J Bone Miner Res 20:1228–1234PubMedCrossRef Tracy JK, Meyer WA, Flores RH, Wilson PD, Hochberg MC (2005) Racial differences in rate of decline in bone mass in older men: the Baltimore men’s osteoporosis study. J Bone Miner Res 20:1228–1234PubMedCrossRef
17.
go back to reference Villa ML (1994) Cultural determinants of skeletal health: the need to consider both race and ethnicity in bone research. J Bone Miner Res 9:1329–1332PubMed Villa ML (1994) Cultural determinants of skeletal health: the need to consider both race and ethnicity in bone research. J Bone Miner Res 9:1329–1332PubMed
18.
go back to reference Bauer RL (1988) Ethnic differences in hip fracture: a reduced incidence in Mexican Americans. Am J Epidemiol 127:145–149PubMed Bauer RL (1988) Ethnic differences in hip fracture: a reduced incidence in Mexican Americans. Am J Epidemiol 127:145–149PubMed
19.
go back to reference Bauer RL, Deyo RA (1987) Low risk of vertebral fracture in Mexican American women. Arch Intern Med 147:1437–1439PubMedCrossRef Bauer RL, Deyo RA (1987) Low risk of vertebral fracture in Mexican American women. Arch Intern Med 147:1437–1439PubMedCrossRef
20.
go back to reference Espino DV, Palmer RF, Miles TP, Mouton CP, Wood RC, Bayne NS, Markides KP (2000) Prevalence, incidence, and risk factors associated with hip fractures in community-dwelling older Mexican Americans: results of the Hispanic EPESE study. Establish Population for the Epidemiologic Study for the Elderly. J Am Geriatr Soc 48:1252–1260PubMed Espino DV, Palmer RF, Miles TP, Mouton CP, Wood RC, Bayne NS, Markides KP (2000) Prevalence, incidence, and risk factors associated with hip fractures in community-dwelling older Mexican Americans: results of the Hispanic EPESE study. Establish Population for the Epidemiologic Study for the Elderly. J Am Geriatr Soc 48:1252–1260PubMed
21.
go back to reference Lauderdale DS, Jacobsen SJ, Furner SE, Levy PS, Brody JA, Goldberg J (1998) Hip fracture incidence among elderly Hispanics. Am J Public Health 88:1245–1247PubMedCrossRef Lauderdale DS, Jacobsen SJ, Furner SE, Levy PS, Brody JA, Goldberg J (1998) Hip fracture incidence among elderly Hispanics. Am J Public Health 88:1245–1247PubMedCrossRef
22.
go back to reference Maggi S, Kelsey JL, Litvak J, Heyse SP (1991) Incidence of hip fractures in the elderly: a cross-national analysis. Osteoporos Int 1:232–241PubMed Maggi S, Kelsey JL, Litvak J, Heyse SP (1991) Incidence of hip fractures in the elderly: a cross-national analysis. Osteoporos Int 1:232–241PubMed
23.
go back to reference Silverman SL, Madison RE (1988) Decreased incidence of hip fracture in Hispanics, Asians, and blacks: California Hospital Discharge Data. Am J Public Health 78:1482–1483PubMedCrossRef Silverman SL, Madison RE (1988) Decreased incidence of hip fracture in Hispanics, Asians, and blacks: California Hospital Discharge Data. Am J Public Health 78:1482–1483PubMedCrossRef
24.
go back to reference Villa ML, Marcus R, Ramirez Delay R, Kelsey JL (1995) Factors contributing to skeletal health of postmenopausal Mexican-American women. J Bone Miner Res 10:1233–1242PubMedCrossRef Villa ML, Marcus R, Ramirez Delay R, Kelsey JL (1995) Factors contributing to skeletal health of postmenopausal Mexican-American women. J Bone Miner Res 10:1233–1242PubMedCrossRef
25.
go back to reference Zingmond DS, Melton LJ 3rd, Silverman SL (2004) Increasing hip fracture incidence in California Hispanics, 1983 to 2000. Osteoporos Int 15:603–610PubMedCrossRef Zingmond DS, Melton LJ 3rd, Silverman SL (2004) Increasing hip fracture incidence in California Hispanics, 1983 to 2000. Osteoporos Int 15:603–610PubMedCrossRef
26.
go back to reference Rumbaut RG (2006) The making of a people. In: Tienda M, Mitchell F (eds) Hispanics and the Future of American Panel on Hispanics in the United States. The National Academies Press, Washington, DC, pp 16–65 Rumbaut RG (2006) The making of a people. In: Tienda M, Mitchell F (eds) Hispanics and the Future of American Panel on Hispanics in the United States. The National Academies Press, Washington, DC, pp 16–65
27.
go back to reference Clark P, de la Pena F, Gomez Garcia F, Orozco JA, Tugwell P (1998) Risk factors for osteoporotic hip fractures in Mexicans. Arch Med Res 29:253–257PubMed Clark P, de la Pena F, Gomez Garcia F, Orozco JA, Tugwell P (1998) Risk factors for osteoporotic hip fractures in Mexicans. Arch Med Res 29:253–257PubMed
28.
go back to reference Elffors I, Allander E, Kanis JA, Gullberg B, Johnell O, Dequeker J, Dilsen G, Gennari C, Lopes Vaz AA, Lyritis G et al (1994) The variable incidence of hip fracture in southern Europe: the MEDOS Study. Osteoporos Int 4:253–263PubMedCrossRef Elffors I, Allander E, Kanis JA, Gullberg B, Johnell O, Dequeker J, Dilsen G, Gennari C, Lopes Vaz AA, Lyritis G et al (1994) The variable incidence of hip fracture in southern Europe: the MEDOS Study. Osteoporos Int 4:253–263PubMedCrossRef
29.
go back to reference Kanis JA, Johnell O, De Laet C, Jonsson B, Oden A, Ogelsby AK (2002) International variations in hip fracture probabilities: implications for risk assessment. J Bone Miner Res 17:1237–1244PubMedCrossRef Kanis JA, Johnell O, De Laet C, Jonsson B, Oden A, Ogelsby AK (2002) International variations in hip fracture probabilities: implications for risk assessment. J Bone Miner Res 17:1237–1244PubMedCrossRef
30.
go back to reference McKinlay JB, Link CL (2007) Measuring the Urologic Iceberg: Design and Implementation of The Boston Area Community Health (BACH) Survey. Eur Urol McKinlay JB, Link CL (2007) Measuring the Urologic Iceberg: Design and Implementation of The Boston Area Community Health (BACH) Survey. Eur Urol
31.
go back to reference Washburn RA, Smith KW, Jette AM, Janney CA (1993) The Physical Activity Scale for the Elderly (PASE): development and evaluation. J Clin Epidemiol 46:153–162PubMedCrossRef Washburn RA, Smith KW, Jette AM, Janney CA (1993) The Physical Activity Scale for the Elderly (PASE): development and evaluation. J Clin Epidemiol 46:153–162PubMedCrossRef
32.
go back to reference Washburn RA, McAuley E, Katula J, Mihalko SL, Boileau RA (1999) The physical activity scale for the elderly (PASE): evidence for validity. J Clin Epidemiol 52:643–651PubMedCrossRef Washburn RA, McAuley E, Katula J, Mihalko SL, Boileau RA (1999) The physical activity scale for the elderly (PASE): evidence for validity. J Clin Epidemiol 52:643–651PubMedCrossRef
33.
go back to reference Wallman K (1997) Data on race and ethnicity: Revising the federal standard. Am Stat 31–35 Wallman K (1997) Data on race and ethnicity: Revising the federal standard. Am Stat 31–35
34.
go back to reference Chen TC, Turner AK, Holick MF (1990) Methods for the determination of the circulating concentration of 25-hydroxyvitamin D. J Nutr Biochem 1:315–319PubMedCrossRef Chen TC, Turner AK, Holick MF (1990) Methods for the determination of the circulating concentration of 25-hydroxyvitamin D. J Nutr Biochem 1:315–319PubMedCrossRef
35.
go back to reference Holick MF, Siris ES, Binkley N, Beard MK, Khan A, Katzer JT, Petruschke RA, Chen E, de Papp AE (2005) Prevalence of Vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy. J Clin Endocrinol Metab 90:3215–3224PubMedCrossRef Holick MF, Siris ES, Binkley N, Beard MK, Khan A, Katzer JT, Petruschke RA, Chen E, de Papp AE (2005) Prevalence of Vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy. J Clin Endocrinol Metab 90:3215–3224PubMedCrossRef
36.
go back to reference World Health Organization (1994) WHO Technical Report Series 843: Assessment of Fracture Risk and its Application to Screening for Postmenopausal Osteoporosis: Report of a WHO Study Group. World Health Organization, Geneva World Health Organization (1994) WHO Technical Report Series 843: Assessment of Fracture Risk and its Application to Screening for Postmenopausal Osteoporosis: Report of a WHO Study Group. World Health Organization, Geneva
38.
go back to reference Looker AC, Orwoll ES, Johnston CC, Lindsay RL, Wahner HW, Dunn WL, Calvo MS, Harris TB, Heyse SP (1997) Prevalence of low femoral bone density in older U.S. adults from NHANES III. J Bone Miner Res 12:1761–1768PubMedCrossRef Looker AC, Orwoll ES, Johnston CC, Lindsay RL, Wahner HW, Dunn WL, Calvo MS, Harris TB, Heyse SP (1997) Prevalence of low femoral bone density in older U.S. adults from NHANES III. J Bone Miner Res 12:1761–1768PubMedCrossRef
39.
go back to reference Hannan MT, Litman HJ, Araujo AB, McLennan CE, McLean RR, McKinlay JB, Chen TC, Holick MF (2008) Serum 25-hydroxyvitamin D and bone mineral density in a racially and ethnically diverse group of men. J Clin Endocrinol Metab 93:40–46PubMedCrossRef Hannan MT, Litman HJ, Araujo AB, McLennan CE, McLean RR, McKinlay JB, Chen TC, Holick MF (2008) Serum 25-hydroxyvitamin D and bone mineral density in a racially and ethnically diverse group of men. J Clin Endocrinol Metab 93:40–46PubMedCrossRef
40.
go back to reference Harris SS, Soteriades E, Coolidge JA, Mudgal S, Dawson-Hughes B (2000) Vitamin D insufficiency and hyperparathyroidism in a low income, multiracial, elderly population. J Clin Endocrinol Metab 85:4125–4130PubMedCrossRef Harris SS, Soteriades E, Coolidge JA, Mudgal S, Dawson-Hughes B (2000) Vitamin D insufficiency and hyperparathyroidism in a low income, multiracial, elderly population. J Clin Endocrinol Metab 85:4125–4130PubMedCrossRef
41.
go back to reference Binkley N, Krueger D, Cowgill CS, Plum L, Lake E, Hansen KE, DeLuca HF, Drezner MK (2004) Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization. J Clin Endocrinol Metab 89:3152–3157PubMedCrossRef Binkley N, Krueger D, Cowgill CS, Plum L, Lake E, Hansen KE, DeLuca HF, Drezner MK (2004) Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization. J Clin Endocrinol Metab 89:3152–3157PubMedCrossRef
42.
go back to reference Lips P, Chapuy MC, Dawson-Hughes B, Pols HA, Holick MF (1999) An international comparison of serum 25-hydroxyvitamin D measurements. Osteoporos Int 9:394–397PubMedCrossRef Lips P, Chapuy MC, Dawson-Hughes B, Pols HA, Holick MF (1999) An international comparison of serum 25-hydroxyvitamin D measurements. Osteoporos Int 9:394–397PubMedCrossRef
43.
go back to reference Tothill P, Hannan WJ (2000) Comparisons between Hologic QDR 1000W, QDR 4500A, and Lunar Expert dual-energy X-ray absorptiometry scanners used for measuring total body bone and soft tissue. Ann N Y Acad Sci 904:63–71PubMedCrossRef Tothill P, Hannan WJ (2000) Comparisons between Hologic QDR 1000W, QDR 4500A, and Lunar Expert dual-energy X-ray absorptiometry scanners used for measuring total body bone and soft tissue. Ann N Y Acad Sci 904:63–71PubMedCrossRef
44.
go back to reference Cooper GS, Umbach DM (1996) Are vitamin D receptor polymorphisms associated with bone mineral density? A meta-analysis. J Bone Miner Res 11:1841–1849PubMed Cooper GS, Umbach DM (1996) Are vitamin D receptor polymorphisms associated with bone mineral density? A meta-analysis. J Bone Miner Res 11:1841–1849PubMed
45.
go back to reference Fang Y, van Meurs JB, d’Alesio A, Jhamai M, Zhao H, Rivadeneira F, Hofman A, van Leeuwen JP, Jehan F, Pols HA, Uitterlinden AG (2005) Promoter and 3¢-untranslated-region haplotypes in the vitamin d receptor gene predispose to osteoporotic fracture: the rotterdam study. Am J Hum Genet 77:807–823PubMedCrossRef Fang Y, van Meurs JB, d’Alesio A, Jhamai M, Zhao H, Rivadeneira F, Hofman A, van Leeuwen JP, Jehan F, Pols HA, Uitterlinden AG (2005) Promoter and 3¢-untranslated-region haplotypes in the vitamin d receptor gene predispose to osteoporotic fracture: the rotterdam study. Am J Hum Genet 77:807–823PubMedCrossRef
46.
go back to reference Harris SS, Eccleshall TR, Gross C, Dawson-Hughes B, Feldman D (1997) The vitamin D receptor start codon polymorphism (FokI) and bone mineral density in premenopausal American black and white women. J Bone Miner Res 12:1043–1048PubMedCrossRef Harris SS, Eccleshall TR, Gross C, Dawson-Hughes B, Feldman D (1997) The vitamin D receptor start codon polymorphism (FokI) and bone mineral density in premenopausal American black and white women. J Bone Miner Res 12:1043–1048PubMedCrossRef
47.
go back to reference Nelson DA, Vande Vord PJ, Wooley PH (2000) Polymorphism in the vitamin D receptor gene and bone mass in African-American and white mothers and children: a preliminary report. Ann Rheum Dis 59:626–630PubMedCrossRef Nelson DA, Vande Vord PJ, Wooley PH (2000) Polymorphism in the vitamin D receptor gene and bone mass in African-American and white mothers and children: a preliminary report. Ann Rheum Dis 59:626–630PubMedCrossRef
48.
go back to reference Holick MF (2004) Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr 80:1678S–1688SPubMed Holick MF (2004) Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr 80:1678S–1688SPubMed
49.
go back to reference Chen TC, Chimeh F, Lu Z, Mathieu J, Person KS, Zhang A, Kohn N, Martinello S, Berkowitz R, Holick MF (2007) Factors that influence the cutaneous synthesis and dietary sources of vitamin D. Arch Biochem Biophys 460:213–217PubMedCrossRef Chen TC, Chimeh F, Lu Z, Mathieu J, Person KS, Zhang A, Kohn N, Martinello S, Berkowitz R, Holick MF (2007) Factors that influence the cutaneous synthesis and dietary sources of vitamin D. Arch Biochem Biophys 460:213–217PubMedCrossRef
50.
go back to reference Choudhry S, Coyle NE, Tang H, Salari K, Lind D, Clark SL, Tsai HJ, Naqvi M, Phong A, Ung N, Matallana H, Avila PC, Casal J, Torres A, Nazario S, Castro R, Battle NC, Perez-Stable EJ, Kwok PY, Sheppard D, Shriver MD, Rodriguez-Cintron W, Risch N, Ziv E, Burchard EG (2006) Population stratification confounds genetic association studies among Latinos. Hum Genet 118:652–664PubMedCrossRef Choudhry S, Coyle NE, Tang H, Salari K, Lind D, Clark SL, Tsai HJ, Naqvi M, Phong A, Ung N, Matallana H, Avila PC, Casal J, Torres A, Nazario S, Castro R, Battle NC, Perez-Stable EJ, Kwok PY, Sheppard D, Shriver MD, Rodriguez-Cintron W, Risch N, Ziv E, Burchard EG (2006) Population stratification confounds genetic association studies among Latinos. Hum Genet 118:652–664PubMedCrossRef
51.
go back to reference Hanis CL, Hewett-Emmett D, Bertin TK, Schull WJ (1991) Origins of U.S. Hispanics. Implications for diabetes. Diabetes Care 14:618–627PubMedCrossRef Hanis CL, Hewett-Emmett D, Bertin TK, Schull WJ (1991) Origins of U.S. Hispanics. Implications for diabetes. Diabetes Care 14:618–627PubMedCrossRef
52.
go back to reference Binkley NC, Schmeer P, Wasnich RD, Lenchik L (2002) What are the criteria by which a densitometric diagnosis of osteoporosis can be made in males and non-Caucasians? J Clin Densitom 5(Suppl):S19–27PubMedCrossRef Binkley NC, Schmeer P, Wasnich RD, Lenchik L (2002) What are the criteria by which a densitometric diagnosis of osteoporosis can be made in males and non-Caucasians? J Clin Densitom 5(Suppl):S19–27PubMedCrossRef
53.
go back to reference Lara M, Gamboa C, Kahramanian MI, Morales LS, Bautista DE (2005) Acculturation and Latino health in the United States: a review of the literature and its sociopolitical context. Annu Rev Public Health 26:367–397PubMedCrossRef Lara M, Gamboa C, Kahramanian MI, Morales LS, Bautista DE (2005) Acculturation and Latino health in the United States: a review of the literature and its sociopolitical context. Annu Rev Public Health 26:367–397PubMedCrossRef
54.
go back to reference Melton LJ 3rd, Marquez MA, Achenbach SJ, Tefferi A, O’Connor MK, O’Fallon WM, Riggs BL (2002) Variations in bone density among persons of African heritage. Osteoporos Int 13:551–559CrossRef Melton LJ 3rd, Marquez MA, Achenbach SJ, Tefferi A, O’Connor MK, O’Fallon WM, Riggs BL (2002) Variations in bone density among persons of African heritage. Osteoporos Int 13:551–559CrossRef
55.
go back to reference Bonilla C, Shriver MD, Parra EJ, Jones A, Fernandez JR (2004) Ancestral proportions and their association with skin pigmentation and bone mineral density in Puerto Rican women from New York city. Hum Genet 115:57–68PubMedCrossRef Bonilla C, Shriver MD, Parra EJ, Jones A, Fernandez JR (2004) Ancestral proportions and their association with skin pigmentation and bone mineral density in Puerto Rican women from New York city. Hum Genet 115:57–68PubMedCrossRef
56.
go back to reference Leslie WD, Tsang JF, Caetano PA, Lix LM (2007) Effectiveness of bone density measurement for predicting osteoporotic fractures in clinical practice. J Clin Endocrinol Metab 92:77–81PubMedCrossRef Leslie WD, Tsang JF, Caetano PA, Lix LM (2007) Effectiveness of bone density measurement for predicting osteoporotic fractures in clinical practice. J Clin Endocrinol Metab 92:77–81PubMedCrossRef
57.
go back to reference Marshall D, Johnell O, Wedel H (1996) Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ 312:1254–1259PubMed Marshall D, Johnell O, Wedel H (1996) Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ 312:1254–1259PubMed
Metadata
Title
Serum 25-hydroxyvitamin D and bone mineral density among Hispanic men
Authors
A. B. Araujo
T. G. Travison
G. R. Esche
M. F. Holick
T. C. Chen
J. B. McKinlay
Publication date
01-02-2009
Publisher
Springer-Verlag
Published in
Osteoporosis International / Issue 2/2009
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-008-0652-9

Other articles of this Issue 2/2009

Osteoporosis International 2/2009 Go to the issue