Published in:
01-05-2007 | Letter to the Editor
Calcium-PTH-vitamin D axis in older patients with hip fracture
Authors:
A. A. Fisher, M. W. Davis
Published in:
Osteoporosis International
|
Issue 5/2007
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Excerpt
We read with interest the article by Sakuma and colleagues [
1] dealing with the controversial issue of vitamin D-PTH status in hip fracture (HF) patients. With an ageing population and exponentially increasing numbers of HFs worldwide, it is important to clarify the contribution of abnormalities in calcium-PTH-vitamin D relationships to HFs. Adequate vitamin D-PTH status is paramount in calcium homeostasis and for bone health. However, recent large randomised controlled trials [
2‐
4] as well as systemic reviews [
5‐
7] contrary to a previous meta-analysis [
8] did not find that supplementation with vitamin D and calcium reduces HFs, except in frail people confined to institutions [
7]. …