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Osteoporosis International
Published in: Osteoporosis International 10/2006

01-10-2006 | Hot Stuff

Osteocytes—martyrs for integrity of bone strength

Author: E. Seeman

Published in: Osteoporosis International | Issue 10/2006

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Excerpt

The structure of bone determines the loads it tolerates. The reverse also applies—the loads imposed on bone determine its structure [1‐3]. This remarkable phenomenon of adaptation is achieved by the cellular machinery of bone modeling and remodeling. Bone modelling is the construction of the skeleton by bone formation without prior bone resorption. Bone remodelling is the reconstruction of the skeleton by bone resorption followed by bone formation at discrete points on the endosteal envelope, and to a lesser extent on the periosteal envelope [5]. …
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Metadata
Title
Osteocytes—martyrs for integrity of bone strength
Author
E. Seeman
Publication date
01-10-2006
Publisher
Springer-Verlag
Published in
Osteoporosis International / Issue 10/2006
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-006-0220-0

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