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Published in: International Urogynecology Journal 4/2021

Open Access 01-04-2021 | Hysterectomy | Original Article

Pelvic organ prolapse after laparoscopic hysterectomy compared with vaginal hysterectomy: the POP-UP study

Authors: Carolien K. M. Vermeulen, Joggem Veen, Caroline Adang, Sanne A. L. van Leijsen, Anne-Lotte W. M. Coolen, Marlies Y. Bongers

Published in: International Urogynecology Journal | Issue 4/2021

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Abstract

Introduction and hypothesis

The objective was to review the long-term prevalence of pelvic organ prolapse (POP) after laparoscopic hysterectomy (LH) compared with vaginal hysterectomy (VH).

Methods

An observational cohort study was conducted amongst women who underwent an LH or a VH for benign indications during the period 1996–2004: the POP-UP study. The prevalence of POP was inventoried by a questionnaire involving the Pelvic Floor Distress Inventory (PFDI-20) and a pelvic floor examination (POP-Q). Women were divided into groups based on route and indication of hysterectomy: LH, VH-1 (for nonprolapse), and VH-2 (prolapse).

Results

Four hundred and six of the 706 eligible patients (58%) returned the questionnaire and 247 underwent POP-Q examination. Sixty-eight patients (17%) received treatment for prolapse; 8% LH, 10% VH-1, and 29% VH-2 (Chi-squared test, p < 0.001). The prevalence of vaginal vault prolapse (apical surgery or ≥ stage 2 at POP-Q) was 4.4% for LH and 5.8% for VH-1 (p = 0.707); and 23% for VH-2 (VH-2 versus others, p < 0.0001). The prevalence of prolapse ≥ stage 2 in any compartment was 62% (n = 153) in total and in 42% of the LH group, 51% of the VH-1 group, and 84% of the VH-2 group (Chi-squared test, p < 0.001). A symptomatic POP (anatomical POP ≥ stage 2 with bulging) was present in 11% of the population.

Conclusions

No difference was found in the prevalence of POP between LH and VH for nonprolapse indications. However, POP after VH for prolapse occurs more frequently than after hysterectomy for other indications.
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Metadata
Title
Pelvic organ prolapse after laparoscopic hysterectomy compared with vaginal hysterectomy: the POP-UP study
Authors
Carolien K. M. Vermeulen
Joggem Veen
Caroline Adang
Sanne A. L. van Leijsen
Anne-Lotte W. M. Coolen
Marlies Y. Bongers
Publication date
01-04-2021
Publisher
Springer International Publishing
Keyword
Hysterectomy
Published in
International Urogynecology Journal / Issue 4/2021
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-020-04591-z

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