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International Urogynecology Journal

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Open Access 01-04-2015 | Original Article

Association between metabolic syndrome and pelvic organ prolapse severity

Authors: A. Rogowski, P. Bienkowski, D. Tarwacki, E. Dziech, J. Samochowiec, M. Jerzak, W. Baranowski

Published in: International Urogynecology Journal | Issue 4/2015

Abstract

Introduction and hypothesis

As in the case of cardiovascular and metabolic diseases, the prevalence of pelvic organ prolapse (POP) has been rising with the increasing proportion of elderly women in the population. The purpose of the present cross-sectional study was to evaluate the components of metabolic syndrome (MS) in urogynecological patients with a variable POP severity.

Methods

The MS risk factors (elevated waist circumference, elevated triglycerides, decreased high-density lipoprotein cholesterol, elevated blood pressure, hyperglycemia) were assessed in 100 women who were referred to our urogynecological center with pelvic floor disorders (PFD). POP was evaluated with the Pelvic Organ Prolapse Quantification system (POP-Q).

Results

The χ ² test revealed that the diagnosis of MS and the presence of elevated triglycerides increased with the overall POP-Q stage. The other MS risk factors were not significantly associated with the overall POP-Q stage. MS and elevated triglycerides were predictors of the POP-Q stage ≥III [odds ratio (OR) 3.5, 95 % confidence interval (CI) 1.5–8.2 for MS and OR 3.4, 95 % CI 1.4–8.2 for elevated triglycerides, p < 0.01].

Conclusions

The diagnosis of MS and the presence of elevated triglycerides may be associated with the severity of POP in urogynecological patients. Longitudinal studies are required to assess whether the MS risk factors might predict the progression of POP and whether elimination of the risk factors might improve the prognosis in POP patients.

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Title: Association between metabolic syndrome and pelvic organ prolapse severity
Authors: A. Rogowski
P. Bienkowski
D. Tarwacki
E. Dziech
J. Samochowiec
M. Jerzak
W. Baranowski
Publication date: 01-04-2015
Publisher: Springer London
Published in: International Urogynecology Journal / Issue 4/2015
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-014-2468-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Association between metabolic syndrome and pelvic organ prolapse severity

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

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