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01-08-2013 | Original Article

The effect of uterine fibroid embolization on lower urinary tract symptoms

Authors: David Shveiky, Cheryl B. Iglesia, Danielle D. Antosh, Bela I. Kudish, Joanna Peterson, Chun-Chin Huang, James B. Spies

Published in: International Urogynecology Journal | Issue 8/2013

Abstract

Introduction and hypothesis

The objective was to determine the effect of uterine fibroid embolization (UFE) on lower urinary tract symptoms (LUTS) and quality of life (QoL).

Methods

This prospective study included women with symptomatic fibroids and LUTS who underwent UFE between March 2008 and May 2010. Subjects underwent pre-procedural pelvic magnetic resonance imaging (MRI) and completed the Urogenital Distress Inventory (UDI-6), Incontinence Impact Questionnaire (IIQ-7), Prolapse and Incontinence Sexual Questionnaire (PISQ-12), Uterine Fibroid Symptom Quality of Life questionnaire (UFS-QoL), and a standardized 48-h bladder diary at baseline and 3 months after the procedure. Patient Global Impression of Improvement (PGI-I) assessed post-procedural patient satisfaction. The primary outcome was subjective improvement in LUTS at 3 months, as measured by a decrease in UDI-6 score. Univariate analysis, paired t test and a stepwise regression analysis were appropriately conducted.

Results

Fifty-seven patients underwent UFE and completed bladder diaries and questionnaires. At 3 months after UFE, patients reported a significant decrease in UDI-6, IIQ-7, and UFS-QoL, indicating an improvement in urinary symptoms and QoL. Bladder diaries showed a significant reduction in daytime and night-time voids. No difference was found in incontinence episodes. Uterine volume, dominant fibroid size, fibroid location, and MRI-confirmed bladder compression did not affect the difference in UDI-6 scores. In a stepwise regression model, BMI had a significant impact on the change in UDI-6 score, with a decrease of 1.18 points for each 1 unit increase in BMI.

Conclusion

Uterine fibroid embolization significantly improves LUTS and urinary-related QoL. Obesity seems to attenuate this effect.

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Title: The effect of uterine fibroid embolization on lower urinary tract symptoms
Authors: David Shveiky
Cheryl B. Iglesia
Danielle D. Antosh
Bela I. Kudish
Joanna Peterson
Chun-Chin Huang
James B. Spies
Publication date: 01-08-2013
Publisher: Springer London
Published in: International Urogynecology Journal / Issue 8/2013
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-012-2013-7

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

The effect of uterine fibroid embolization on lower urinary tract symptoms

Abstract

Introduction and hypothesis

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Introduction and hypothesis

Methods

Results

Conclusion

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