Skip to main content
Top
Published in: International Urogynecology Journal 6/2012

01-06-2012 | Editorial

Ovarian cancer and the pelvic floor surgeon: the case for prophylactic bilateral salpingectomy during POP surgery

Author: Peter L. Dwyer

Published in: International Urogynecology Journal | Issue 6/2012

Login to get access

Excerpt

Ovarian cancer is a leading cause of cancer death in women and has a high mortality rate and a low 5-year survival rate (around 30%). Presentation is typically with late-stage metastatic disease which responds poorly to the conventional treatment of surgery and chemotherapy; most cancer deaths occur in women with high-grade serous ovarian carcinoma [1]. Screening tests employed before symptoms develop using either measurement of CA125 levels, ultrasound, or both have as yet not been proved effective in early detection. Despite extensive research the incidence of ovarian cancer is increasing and the survival rates have not improved significantly over the past decade [1]. …
Literature
1.
go back to reference Piver MS (1996) Prophylactic oophorectomy: reducing the U.S. death rate from epithelial ovarian cancer. A continuing debate. Oncologist 1(5):326–330PubMed Piver MS (1996) Prophylactic oophorectomy: reducing the U.S. death rate from epithelial ovarian cancer. A continuing debate. Oncologist 1(5):326–330PubMed
2.
go back to reference Brown JS, Waetjen LE, Subak LL, Thom DH, Van den Eeden S, Vittinghoff E (2002) Pelvic organ prolapse surgery in the United States, 1997. Am J Obstet Gynecol 186(4):712–716PubMedCrossRef Brown JS, Waetjen LE, Subak LL, Thom DH, Van den Eeden S, Vittinghoff E (2002) Pelvic organ prolapse surgery in the United States, 1997. Am J Obstet Gynecol 186(4):712–716PubMedCrossRef
3.
go back to reference Asante A, Whiteman MK, Kulkarni A, Cox S, Marchbanks PA, Jamieson DJ (2010) Elective oophorectomy in the United States: trends and in-hospital complications, 1998–2006. Obstet Gynecol 116(5):1088–1095PubMedCrossRef Asante A, Whiteman MK, Kulkarni A, Cox S, Marchbanks PA, Jamieson DJ (2010) Elective oophorectomy in the United States: trends and in-hospital complications, 1998–2006. Obstet Gynecol 116(5):1088–1095PubMedCrossRef
4.
go back to reference Brand A (2011) The RANZCOG College Statement on prophylactic oophorectomy in older women undergoing hysterectomy for benign disease: is the evidence sufficient to change practice? Aust N Z J Obstet Gynaecol 51(4):296–300PubMedCrossRef Brand A (2011) The RANZCOG College Statement on prophylactic oophorectomy in older women undergoing hysterectomy for benign disease: is the evidence sufficient to change practice? Aust N Z J Obstet Gynaecol 51(4):296–300PubMedCrossRef
5.
go back to reference Olive DL (2005) Dogma, skepsis, and the analytic method; the role of prophylactic oophorectomy at the time of hysterectomy. Obstet Gynecol 106:214–215PubMedCrossRef Olive DL (2005) Dogma, skepsis, and the analytic method; the role of prophylactic oophorectomy at the time of hysterectomy. Obstet Gynecol 106:214–215PubMedCrossRef
6.
go back to reference Shuster LT, Gostout BS, Grossard BD, Rocca WA (2008) Propylactic oophorectomy in pre-menopausal women and longterm health—a review. Menopause Int 14(3):111–116PubMedCrossRef Shuster LT, Gostout BS, Grossard BD, Rocca WA (2008) Propylactic oophorectomy in pre-menopausal women and longterm health—a review. Menopause Int 14(3):111–116PubMedCrossRef
7.
go back to reference Crum CP, Drapkin R, Kindelberger D, Medeiros F, Miron A, Lee Y (2007) Lessons from BRCA: the tubal fimbria emerges as an origin for pelvic serous cancer. Clin Med Res 5(1):35–44PubMedCrossRef Crum CP, Drapkin R, Kindelberger D, Medeiros F, Miron A, Lee Y (2007) Lessons from BRCA: the tubal fimbria emerges as an origin for pelvic serous cancer. Clin Med Res 5(1):35–44PubMedCrossRef
8.
go back to reference Kindelberger DW, Lee Y, Miron A, Hirsch MS, Feltmate C, Medeiros F, Callahan MJ, Garner EO, Gordon RW, Birch C, Berkowitz RS, Muto MG, Crum CP (2007) Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: evidence for a causal relationship. Am J Surg Pathol 31(2):161–169PubMedCrossRef Kindelberger DW, Lee Y, Miron A, Hirsch MS, Feltmate C, Medeiros F, Callahan MJ, Garner EO, Gordon RW, Birch C, Berkowitz RS, Muto MG, Crum CP (2007) Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: evidence for a causal relationship. Am J Surg Pathol 31(2):161–169PubMedCrossRef
9.
go back to reference Przybycin CG, Kurman RJ, Ronnett BM, Shih IeM, Vang R (2010) Are all pelvic (nonuterine) serous carcinomas of tubal origin? Am J Surg Pathol 34(10):1407–1416PubMedCrossRef Przybycin CG, Kurman RJ, Ronnett BM, Shih IeM, Vang R (2010) Are all pelvic (nonuterine) serous carcinomas of tubal origin? Am J Surg Pathol 34(10):1407–1416PubMedCrossRef
Metadata
Title
Ovarian cancer and the pelvic floor surgeon: the case for prophylactic bilateral salpingectomy during POP surgery
Author
Peter L. Dwyer
Publication date
01-06-2012
Publisher
Springer-Verlag
Published in
International Urogynecology Journal / Issue 6/2012
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-012-1727-x

Other articles of this Issue 6/2012

International Urogynecology Journal 6/2012 Go to the issue