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International Urogynecology Journal
Published in: International Urogynecology Journal 7/2011

01-07-2011 | Original Article

Incidence and management of graft erosion, wound granulation, and dyspareunia following vaginal prolapse repair with graft materials: a systematic review

Authors: Husam Abed, David D. Rahn, Lior Lowenstein, Ethan M. Balk, Jeffrey L. Clemons, Rebecca G. Rogers, For the Systematic Review Group of the Society of Gynecologic Surgeons

Published in: International Urogynecology Journal | Issue 7/2011

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Abstract

Introduction and hypothesis

This study describes the incidence, risk factors, and treatments of graft erosion, wound granulation, and dyspareunia as adverse events following vaginal repair of pelvic organ prolapse with non-absorbable synthetic and biologic graft materials.

Methods

A systematic review in Medline of reports published between 1950 and November 2010 on adverse events after vaginal prolapse repairs using graft materials was carried out.

Results

One hundred ten studies reported on erosions with an overall rate, by meta-analysis, of 10.3%, (95% CI, 9.7 – 10.9%; range, 0 – 29.7%; synthetic, 10.3%; biological, 10.1%). Sixteen studies reported on wound granulation for a rate of 7.8%, (95% CI, 6.4 – 9.5%; range, 0 – 19.1%; synthetic, 6.8%; biological, 9.1%). Dyspareunia was described in 70 studies for a rate of 9.1%, (95% CI, 8.2 – 10.0%; range, 0 – 66.7%; synthetic, 8.9%; biological, 9.6%).

Conclusions

Erosions, wound granulation, and dyspareunia may occur after vaginal prolapse repair with graft materials, though rates vary widely across studies.
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Metadata
Title
Incidence and management of graft erosion, wound granulation, and dyspareunia following vaginal prolapse repair with graft materials: a systematic review
Authors
Husam Abed
David D. Rahn
Lior Lowenstein
Ethan M. Balk
Jeffrey L. Clemons
Rebecca G. Rogers
For the Systematic Review Group of the Society of Gynecologic Surgeons
Publication date
01-07-2011
Publisher
Springer-Verlag
Published in
International Urogynecology Journal / Issue 7/2011
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-011-1384-5

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