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International Urogynecology Journal

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01-09-2010 | Original Article

In vivo assessment of anterior compartment compliance and its relation to prolapse

Authors: Yvonne Hsu, Luyun Chen, Julie Tumbarello, James A. Ashton-Miller, John O. L. DeLancey

Published in: International Urogynecology Journal | Issue 9/2010

Abstract

Introduction and hypothesis

The objective of the study was to compare anterior compartment compliance between women with and without pelvic organ prolapse and to explore factors determining the extent of anterior compartment prolapse.

Methods

Ten women with normal pelvic support and nine with anterior compartment prolapse were analyzed. Abdominal pressure was measured during Valsalva and simultaneous midsagittal dynamic MR imaging. The distance between the most dependent anterior vaginal wall point and a previously determined average nulliparous anterior vaginal wall point was measured. A best-fit line was determined when anterior vaginal wall displacement was plotted relative to abdominal pressure. The slope of this line is a measure of anterior compartment compliance. Multivariate analyses and t tests were performed.

Results

Mean compliance (centimeters per centimeter of water) was higher for cases [0.05 ± 0.006 standard error of the mean (SEM)] than controls (0.03 ± .007, p = 0.039). Degree of anterior compartment prolapse correlated best with compliance (R ² = 0.75, p < 0.01) and also with resting anterior vaginal wall point (R ² = 0.55, p < 0.01).

Conclusions

Women with anterior compartment prolapse have a 67% more compliant support system compared with those with normal support. Both compliance and resting anterior vaginal wall location are predictors of the degree of anterior compartment prolapse.

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Title: In vivo assessment of anterior compartment compliance and its relation to prolapse
Authors: Yvonne Hsu
Luyun Chen
Julie Tumbarello
James A. Ashton-Miller
John O. L. DeLancey
Publication date: 01-09-2010
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 9/2010
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-010-1154-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

In vivo assessment of anterior compartment compliance and its relation to prolapse

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

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