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Published in: International Urogynecology Journal 7/2010

01-07-2010 | Original Article

Depressive symptoms in women seeking surgery for pelvic organ prolapse

Authors: Chiara Ghetti, Jerry L. Lowder, Rennique Ellison, M. A. Krohn, Pamela Moalli

Published in: International Urogynecology Journal | Issue 7/2010

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Abstract

Introduction and hypothesis

To compare depressive symptoms in women with and without prolapse and evaluate impact on quality of life.

Methods

This is a secondary analysis of a case–control study assessing the effect of prolapse on body image. Cases had prolapse and sought surgery (Pelvic Organ Prolapse Quantification stage ≥2). Controls had stage ≤1. Subjects completed the Pelvic Floor Impact Questionnaire (PFIQ), Pelvic Floor Distress Inventory, and the Patient Health Questionnaire-9 (PHQ-9) at baseline. Cases completed measures 6 months post-operatively. We report: (1) the comparison of cases and controls at baseline and (2) comparison of baseline and post-operative scores in cases.

Results

Baseline questionnaires were completed by 75 cases and 65 controls; 57 cases completed post-operative measures. Cases were 5-fold more likely than controls to have depressive symptoms. Cases with depressive symptoms had higher PFIQ scores than cases without symptoms. PHQ-9 scores improved post-operatively.

Conclusions

Depressive symptoms are common in women with prolapse and a decrease following surgical treatment.
Literature
1.
go back to reference Ghetti C, Gregory WT, Edwards SR, Clark AL (2005) Pelvic organ descent and the perception of prolapse. Am J Obstet Gynecol 193(1):53–57CrossRefPubMed Ghetti C, Gregory WT, Edwards SR, Clark AL (2005) Pelvic organ descent and the perception of prolapse. Am J Obstet Gynecol 193(1):53–57CrossRefPubMed
2.
go back to reference Subak LL, Waetjen LE, van den Eeden S, Thom DH, Vittinghoff E, Brown JS (2001) Cost of pelvic organ prolapse surgery in the United States. Obstet Gynecol 98:646–651CrossRefPubMed Subak LL, Waetjen LE, van den Eeden S, Thom DH, Vittinghoff E, Brown JS (2001) Cost of pelvic organ prolapse surgery in the United States. Obstet Gynecol 98:646–651CrossRefPubMed
3.
go back to reference Olsen AL, Smith VJ, Bergstrom JO, Colling JC, Clark AL (1997) Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence. Obstet Gynecol 89:501–506CrossRefPubMed Olsen AL, Smith VJ, Bergstrom JO, Colling JC, Clark AL (1997) Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence. Obstet Gynecol 89:501–506CrossRefPubMed
4.
go back to reference Luber KM, Boero S, Choe JY (2001) The demographics of pelvic floor disorders: current observations and future projections. Am J Obstet Gynecol 184:1496–1451, Discussion 1501–3CrossRefPubMed Luber KM, Boero S, Choe JY (2001) The demographics of pelvic floor disorders: current observations and future projections. Am J Obstet Gynecol 184:1496–1451, Discussion 1501–3CrossRefPubMed
5.
go back to reference Melville JL, Walker E, Katon W, Lentz G, Miller J, Fenner D (2002) Prevalence of comorbid psychiatric illness and its impact on symptom perception, quality of life, and functional status in women with urinary incontinence. Am J Obstet Gynecol 187:80–87CrossRefPubMed Melville JL, Walker E, Katon W, Lentz G, Miller J, Fenner D (2002) Prevalence of comorbid psychiatric illness and its impact on symptom perception, quality of life, and functional status in women with urinary incontinence. Am J Obstet Gynecol 187:80–87CrossRefPubMed
6.
go back to reference Nygaard I, Turvey C, Burns TL, Crischilles E, Wallace R (2003) Urinary incontinence and depression in middle-aged United States women. Obstet Gynecol 101:149–156CrossRefPubMed Nygaard I, Turvey C, Burns TL, Crischilles E, Wallace R (2003) Urinary incontinence and depression in middle-aged United States women. Obstet Gynecol 101:149–156CrossRefPubMed
7.
go back to reference Melville JL, Delaney K, Newton K, Katon W (2005) Incontinence severity and major depression in incontinent women. Obstet Gynecol 106:585–592PubMed Melville JL, Delaney K, Newton K, Katon W (2005) Incontinence severity and major depression in incontinent women. Obstet Gynecol 106:585–592PubMed
8.
go back to reference Ustun TB, Ayuso-Mateos JL, Chatterji S, Mathers C, Murray CJ (2004) Global burden of depressive disorders in the year 2000. Br J Psychiatry 184:386–392CrossRefPubMed Ustun TB, Ayuso-Mateos JL, Chatterji S, Mathers C, Murray CJ (2004) Global burden of depressive disorders in the year 2000. Br J Psychiatry 184:386–392CrossRefPubMed
9.
go back to reference Barber MD, Walters MD, Cundiff GW (2006) Responsiveness of the Pelvic Floor Distress Inventory (PFDI) and Pelvic Floor Impact Questionnaire (PFIQ) in women undergoing vaginal surgery and pessary treatment for pelvic organ prolapse. Am J Obstet Gynecol 194:1492–1498CrossRefPubMed Barber MD, Walters MD, Cundiff GW (2006) Responsiveness of the Pelvic Floor Distress Inventory (PFDI) and Pelvic Floor Impact Questionnaire (PFIQ) in women undergoing vaginal surgery and pessary treatment for pelvic organ prolapse. Am J Obstet Gynecol 194:1492–1498CrossRefPubMed
10.
go back to reference Kroenke K, Spitzer RL, Williams JB (2001) The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med 16:606–613CrossRefPubMed Kroenke K, Spitzer RL, Williams JB (2001) The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med 16:606–613CrossRefPubMed
11.
go back to reference Bump RC, Mattiasson A, Bo K et al (1996) The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. Am J Obstet Gynecol 175:10–17CrossRefPubMed Bump RC, Mattiasson A, Bo K et al (1996) The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. Am J Obstet Gynecol 175:10–17CrossRefPubMed
12.
go back to reference Spitzer RL, Williams JB, Kroenke K, Hornyak R, McMurray J (2000) Validity and utility of the PRIME-MD patient health questionnaire in assessment of 3000 obstetric-gynecologic patients: the PRIME-MD Patient Health Questionnaire Obstetrics–Gynecology Study. Am J Obstet Gynecol 183:759–769CrossRefPubMed Spitzer RL, Williams JB, Kroenke K, Hornyak R, McMurray J (2000) Validity and utility of the PRIME-MD patient health questionnaire in assessment of 3000 obstetric-gynecologic patients: the PRIME-MD Patient Health Questionnaire Obstetrics–Gynecology Study. Am J Obstet Gynecol 183:759–769CrossRefPubMed
13.
go back to reference Rosner B (2000) Fundamentals of biostatistics, 5th edn. Brooks/Cole, Duxbury Thomson Learning, Pacific Grove Rosner B (2000) Fundamentals of biostatistics, 5th edn. Brooks/Cole, Duxbury Thomson Learning, Pacific Grove
14.
go back to reference Barber MD, Kuchibhatla MN, Pieper CF, Bump RC (2001) Psychometric evaluation of 2 comprehensive condition-specific quality of life instruments for women with pelvic floor disorders. Am J Obstet Gynecol 185:1388–1395CrossRefPubMed Barber MD, Kuchibhatla MN, Pieper CF, Bump RC (2001) Psychometric evaluation of 2 comprehensive condition-specific quality of life instruments for women with pelvic floor disorders. Am J Obstet Gynecol 185:1388–1395CrossRefPubMed
15.
go back to reference Little RJA, Rubin DB (1987) Statistical analysis with missing data. Wiley, New York Little RJA, Rubin DB (1987) Statistical analysis with missing data. Wiley, New York
16.
go back to reference Shrive FM, Stuart H, Quan H, Ghali WA (2006) Dealing with missing data in a multi-question depression scale: a comparison of imputation methods. BMC Med Res Methodol 6:57CrossRefPubMed Shrive FM, Stuart H, Quan H, Ghali WA (2006) Dealing with missing data in a multi-question depression scale: a comparison of imputation methods. BMC Med Res Methodol 6:57CrossRefPubMed
17.
go back to reference Kamolz T, Granderath FA, Pointner R (2003) Does major depression in patients with gastroesophageal reflux disease affect the outcome of laparoscopic antireflux surgery? Surg Endosc 17:55–60CrossRefPubMed Kamolz T, Granderath FA, Pointner R (2003) Does major depression in patients with gastroesophageal reflux disease affect the outcome of laparoscopic antireflux surgery? Surg Endosc 17:55–60CrossRefPubMed
18.
go back to reference Connerney I, Shapiro PA, McLaughlin JS, Bagiella E, Sloan RP (2001) Relation between depression after coronary artery bypass surgery and 12-month outcome: a prospective study. Lancet 358:1766–1771CrossRefPubMed Connerney I, Shapiro PA, McLaughlin JS, Bagiella E, Sloan RP (2001) Relation between depression after coronary artery bypass surgery and 12-month outcome: a prospective study. Lancet 358:1766–1771CrossRefPubMed
19.
go back to reference Heck DA, Robinson RL, Partridge CM, Lubitz RM, Freund DA (1998) Patient outcomes after knee replacement. Clin Orthop Relat Res 356:93–110CrossRefPubMed Heck DA, Robinson RL, Partridge CM, Lubitz RM, Freund DA (1998) Patient outcomes after knee replacement. Clin Orthop Relat Res 356:93–110CrossRefPubMed
20.
go back to reference Lenze EJ, Munin MC, Dew MA et al (2004) Adverse effects of depression and cognitive impairment on rehabilitation participation and recovery from hip fracture. Int J Geriatr Psychiatry 19:472–478CrossRefPubMed Lenze EJ, Munin MC, Dew MA et al (2004) Adverse effects of depression and cognitive impairment on rehabilitation participation and recovery from hip fracture. Int J Geriatr Psychiatry 19:472–478CrossRefPubMed
Metadata
Title
Depressive symptoms in women seeking surgery for pelvic organ prolapse
Authors
Chiara Ghetti
Jerry L. Lowder
Rennique Ellison
M. A. Krohn
Pamela Moalli
Publication date
01-07-2010
Publisher
Springer-Verlag
Published in
International Urogynecology Journal / Issue 7/2010
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-010-1106-4

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