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01-12-2007 | Original Article

Impact of pregnancy and childbirth on female rats’ urethral nerve fibers

Authors: M. A. Rocha, M. G. F. Sartori, M. De Jesus Simões, V. Herrmann, E. C. Baracat, G. Rodrigues de Lima, M. J. B. C. Girão

Published in: International Urogynecology Journal | Issue 12/2007

Abstract

This study aims to evaluate the urethral nerve fibers of adult female rats during pregnancy and after vaginal birth, cesarean section or simulated birth trauma. For immunohistochemical analysis of nerve fibers, 70 female rats were distributed in seven groups of ten female rats: group 1, control; group 2, pregnant; group 3, cesarean section; group 4, vaginal birth; group 5, virgin female rats with simulated birth trauma; group 6, cesarean section followed by simulation of birth trauma; and group 7, vaginal birth followed by simulation of birth trauma. The number of nerve fibers in groups 1, 2, and 3 were significantly higher than the other groups. Pregnancy and cesarean section did not cause alterations in the nerve fibers number. Vaginal birth and simulated birth trauma significantly decreased the number of nerve fibers in the female rats’ middle urethra.

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Title: Impact of pregnancy and childbirth on female rats’ urethral nerve fibers
Authors: M. A. Rocha
M. G. F. Sartori
M. De Jesus Simões
V. Herrmann
E. C. Baracat
G. Rodrigues de Lima
M. J. B. C. Girão
Publication date: 01-12-2007
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 12/2007
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-007-0355-3

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Impact of pregnancy and childbirth on female rats’ urethral nerve fibers

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