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01-04-2006 | 2005 IUGA Grafts Roundtable

The biology behind fascial defects and the use of implants in pelvic organ prolapse repair

Authors: Jan Deprest, Fang Zheng, Maja Konstantinovic, Federico Spelzini, Filip Claerhout, Anneke Steensma, Yves Ozog, Dirk De Ridder

Published in: International Urogynecology Journal | Special Issue 1/2006

Abstract

Implant materials are increasingly being used in an effort to reduce recurrence after prolapse repair with native tissues. Surgeons should be aware of the biology behind both the disease as well as the host response to various implants. We will discuss insights into the biology behind hernia and abdominal fascial defects. Those lessons from “herniology” will, wherever possible, be applied to pelvic organ prolapse (POP) problems. Then we will deal with available animal models, for both the underlying disease and surgical repair. Then we will go over the features of implants and describe how the host responds to implantation. Methodology of such experiments will be briefly explained for the clinician not involved in experimentation. As we discuss the different materials available on the market, we will summarize some results of recent experiments by our group.

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Title: The biology behind fascial defects and the use of implants in pelvic organ prolapse repair
Authors: Jan Deprest
Fang Zheng
Maja Konstantinovic
Federico Spelzini
Filip Claerhout
Anneke Steensma
Yves Ozog
Dirk De Ridder
Publication date: 01-04-2006
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue Special Issue 1/2006
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-006-0101-2

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