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Published in: Knee Surgery, Sports Traumatology, Arthroscopy 2/2020

01-02-2020 | Opioids | KNEE

Preoperative opioid use is associated with inferior outcomes after patellofemoral stabilization surgery

Authors: Zain M. Khazi, Alan G. Shamrock, Christina Hajewski, Natalie Glass, Brian R. Wolf, Kyle R. Duchman, Robert W. Westermann, Matthew Bollier

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 2/2020

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Abstract

Purpose

The purpose of the study was to investigate the association between preoperative opioid use and persistent postoperative use, and determine the impact of preoperative opioid use on patient-reported outcomes (PROs) in patients undergoing patellofemoral stabilization surgery.

Methods

A retrospective analysis of 60 patients after patellofemoral stabilization surgery with a minimum of 2-year follow-up was performed using a prospectively collected patellar instability registry. Patients were categorized as opioid naïve (n = 48) or preoperative opioid users (n = 12). Postoperative opioid use was assessed for all patients at 2 and 6 weeks. Knee Injury and Osteoarthritis Outcome Score (KOOS) and Kujala questionnaires were administered at baseline, and 6 months and 2 years postoperatively.

Results

Preoperative opioid use was identified as an independent risk factor for postoperative opioid use at 2- and 6-weeks following surgery (p = 0.0023 and p < 0.0001, respectively). Preoperative opioid use was associated with significantly lower KOOS and Kujala scores at baseline, 6 months and 2 years postoperatively. Both groups significantly improved from baseline KOOS and Kujala scores at 6 months and 2 years postoperatively. Regardless of preoperative opioid use, opioid use at 6 weeks after surgery was associated with worse KOOS scores at 6 months and 2 years postoperatively.

Conclusion

In patients undergoing patellofemoral stabilization surgery, preoperative opioid use was predictive of postoperative use. Additionally, preoperative opioid use was associated with worse PROs at 6 months and 2 years following surgery.

Level of evidence

III.
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Metadata
Title
Preoperative opioid use is associated with inferior outcomes after patellofemoral stabilization surgery
Authors
Zain M. Khazi
Alan G. Shamrock
Christina Hajewski
Natalie Glass
Brian R. Wolf
Kyle R. Duchman
Robert W. Westermann
Matthew Bollier
Publication date
01-02-2020
Publisher
Springer Berlin Heidelberg
Keywords
Opioids
Opioids
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 2/2020
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-019-05738-2

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