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Published in: Knee Surgery, Sports Traumatology, Arthroscopy 3/2016

01-03-2016 | Knee

A comparison of revision and rerupture rates of ACL reconstruction between autografts and allografts in the skeletally immature

Authors: Ian R. Nelson, Jason Chen, Rebecca Love, Brent R. Davis, Gregory B. Maletis, Tadashi T. Funahashi

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 3/2016

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Abstract

Purpose

Anterior cruciate ligament reconstructions (ACLRs) in skeletally immature patients are increasing. The purpose of this study is to describe the demographics, graft usage, revision, and re-operation rates in skeletally immature ACLRs in the Kaiser Permanente healthcare system.

Methods

Skeletally immature patients (<17.0 years old with open physes) were identified using the Kaiser Permanente ACLR registry. Multi-ligament reconstructions and physeal-sparing ACLRs were excluded. Aseptic revision and same-knee re-operation were the outcomes of interest. Exposure of interest was graft type; bone-patellar-tendon-bone (BPTB) autograft, hamstring autograft, and any type of allograft. Age, gender, body mass index (BMI), and race were evaluated as confounders. Cox proportional hazard models stratified by surgeon were used to analyse the risk of revision and re-operation.

Results

A total of 534 primary ACLR cases were evaluated with a mean follow-up of 2.9 years. The majority were hamstring autografts (n = 388, 72.7 %), male (n = 339, 63.9 %), and White (n = 232, 43.4 %). Median age was 14.9 years, and median BMI was 21.9 kg/m2. There were 44 (8.2 %) aseptic revisions and 48 (9.0 %) same-knee re-operations. The incidence rate for revision was BPTB autograft 5.5 %, hamstring autograft 7.5 %, and allograft 13.2 %. After adjusting for confounders and surgeon clustering effect, the risk of aseptic revision and revision between allograft and hamstring autograft did not reach statistical significance.

Conclusion

Graft selection differs in skeletally immature patients with a preponderance of surgeries being performed with hamstring tendon autografts. High revision rates were identified for all graft types used, though differences in revision rates across different graft types did not reach statistical significance. Surgeons should be aware of high rates of revision in this skeletally immature young population, although type of graft used did not appear to make a difference.

Level of evidence

III.
Literature
1.
go back to reference Al-Hadithy N, Dodds AL, Akhtar KS, Gupte CM (2013) Current concepts of the management of anterior cruciate ligament injuries in children. Bone Joint J 95-B:1562–1569CrossRefPubMed Al-Hadithy N, Dodds AL, Akhtar KS, Gupte CM (2013) Current concepts of the management of anterior cruciate ligament injuries in children. Bone Joint J 95-B:1562–1569CrossRefPubMed
2.
go back to reference Calvo R, Figueroa D, Gili F, Vaisman A, Mocoçain P, Espinosa M, León A, Arellano S (2015) Transphyseal anterior cruciate ligament reconstruction in patients with open physes: 10-year follow-up study. Am J Sports Med 43:289–294CrossRefPubMed Calvo R, Figueroa D, Gili F, Vaisman A, Mocoçain P, Espinosa M, León A, Arellano S (2015) Transphyseal anterior cruciate ligament reconstruction in patients with open physes: 10-year follow-up study. Am J Sports Med 43:289–294CrossRefPubMed
3.
go back to reference Csintalan RP, Inacio MCS, Desmond JL, Funahashi TT (2013) Anterior cruciate ligament reconstruction in patients with open physes: early outcomes. J Knee Surg 26:225–232CrossRefPubMed Csintalan RP, Inacio MCS, Desmond JL, Funahashi TT (2013) Anterior cruciate ligament reconstruction in patients with open physes: early outcomes. J Knee Surg 26:225–232CrossRefPubMed
4.
go back to reference Engelman GH, Carry PM, Hitt KG, Polousky JD, Vidal AF (2014) Comparison of allograft versus autograft anterior cruciate ligament reconstruction graft survival in an active adolescent cohort. Am J Sports Med 42:2311–2318CrossRefPubMed Engelman GH, Carry PM, Hitt KG, Polousky JD, Vidal AF (2014) Comparison of allograft versus autograft anterior cruciate ligament reconstruction graft survival in an active adolescent cohort. Am J Sports Med 42:2311–2318CrossRefPubMed
5.
go back to reference Frosch KH, Stenge LD, Brodhun T, Stietencron I, Holsten D, Jung C, Reister D, Voigt C, Niemeyer P, Maier M et al (2010) Outcomes and risks of operative treatment of rupture of the anterior cruciate ligament in children and adolescents. Arthroscopy 26:1539–1550CrossRefPubMed Frosch KH, Stenge LD, Brodhun T, Stietencron I, Holsten D, Jung C, Reister D, Voigt C, Niemeyer P, Maier M et al (2010) Outcomes and risks of operative treatment of rupture of the anterior cruciate ligament in children and adolescents. Arthroscopy 26:1539–1550CrossRefPubMed
6.
go back to reference Fuchs R, Wheatley W, Uribe JW, Hechtman KS, Zvijac JE, Schurhoff MR (2002) Intra-articular anterior cruciate ligament reconstruction using patellar tendon allograft in the skeletally immature patient. Arthroscopy 18:824–828CrossRefPubMed Fuchs R, Wheatley W, Uribe JW, Hechtman KS, Zvijac JE, Schurhoff MR (2002) Intra-articular anterior cruciate ligament reconstruction using patellar tendon allograft in the skeletally immature patient. Arthroscopy 18:824–828CrossRefPubMed
7.
go back to reference Funahashi KM, Moksnes H, Maletis GB, Csintalan RP, Inacio MC, Funahashi TT (2014) Anterior cruciate ligament injuries in adolescents with open physis: effect of recurrent injury and surgical delay on meniscal and cartilage injuries. Am J Sports Med 42:1068–1073CrossRefPubMed Funahashi KM, Moksnes H, Maletis GB, Csintalan RP, Inacio MC, Funahashi TT (2014) Anterior cruciate ligament injuries in adolescents with open physis: effect of recurrent injury and surgical delay on meniscal and cartilage injuries. Am J Sports Med 42:1068–1073CrossRefPubMed
8.
go back to reference Gifstad T, Foss OA, Engebretsen L, Lind M, Forssblad M, Albrektsen G, Drogset JO (2014) Lower risk of revision with patellar tendon autografts compared with hamstring autografts: a registry study based on 45,998 primary ACL reconstructions in Scandinavia. Am J Sports Med 42:2319–2328CrossRefPubMed Gifstad T, Foss OA, Engebretsen L, Lind M, Forssblad M, Albrektsen G, Drogset JO (2014) Lower risk of revision with patellar tendon autografts compared with hamstring autografts: a registry study based on 45,998 primary ACL reconstructions in Scandinavia. Am J Sports Med 42:2319–2328CrossRefPubMed
9.
go back to reference Hui C, Roe J, Ferguson D, Waller A, Salmon L, Pinczewski L (2012) Outcome of anatomic transphyseal anterior cruciate ligament reconstruction in Tanner stage 1 and 2 patients with open physes. Am J Sports Med 40:1093–1098CrossRefPubMed Hui C, Roe J, Ferguson D, Waller A, Salmon L, Pinczewski L (2012) Outcome of anatomic transphyseal anterior cruciate ligament reconstruction in Tanner stage 1 and 2 patients with open physes. Am J Sports Med 40:1093–1098CrossRefPubMed
10.
go back to reference Kercher J, Xerogeanes J, Tannenbaum A, Al-Hakim R, Black JC, Zhao J (2009) Anterior cruciate ligament reconstruction in the skeletally immature: an anatomical study utilizing 3-dimensional magnetic resonance imaging reconstructions. J Pediatr Orthop 29:124–129PubMedCentralCrossRefPubMed Kercher J, Xerogeanes J, Tannenbaum A, Al-Hakim R, Black JC, Zhao J (2009) Anterior cruciate ligament reconstruction in the skeletally immature: an anatomical study utilizing 3-dimensional magnetic resonance imaging reconstructions. J Pediatr Orthop 29:124–129PubMedCentralCrossRefPubMed
11.
go back to reference Kim SJ, Shim DW, Park KW (2012) Functional outcome of transphyseal reconstruction of the anterior cruciate ligament in skeletally immature patients. Knee Surg Relat Res 24:173–179PubMedCentralCrossRefPubMed Kim SJ, Shim DW, Park KW (2012) Functional outcome of transphyseal reconstruction of the anterior cruciate ligament in skeletally immature patients. Knee Surg Relat Res 24:173–179PubMedCentralCrossRefPubMed
12.
go back to reference Kohl S, Stutz C, Decker S, Ziebarth K, Slongo T, Ahmad SS, Kohlhof H, Eggli S, Zumstein M, Evangelopoulos DS (2014) Mid-term results of transphyseal anterior cruciate ligament reconstruction in children and adolescents. Knee 21:80–85CrossRefPubMed Kohl S, Stutz C, Decker S, Ziebarth K, Slongo T, Ahmad SS, Kohlhof H, Eggli S, Zumstein M, Evangelopoulos DS (2014) Mid-term results of transphyseal anterior cruciate ligament reconstruction in children and adolescents. Knee 21:80–85CrossRefPubMed
13.
go back to reference Lo IK, Kirkley A, Fowler PJ, Miniaci A (1997) The outcome of operatively treated anterior cruciate ligament disruptions in the skeletally immature child. Arthroscopy 13:627–634CrossRefPubMed Lo IK, Kirkley A, Fowler PJ, Miniaci A (1997) The outcome of operatively treated anterior cruciate ligament disruptions in the skeletally immature child. Arthroscopy 13:627–634CrossRefPubMed
14.
go back to reference Maletis GB, Chen J, Inacio MCS, Funahashi TT (2015) Age-related risk factors for revision anterior cruciate ligament reconstruction: a cohort study of 21,304 patients from the Kaiser Permanente Anterior Cruciate Ligament Registry. Am J Sports Med. doi:10.1177/0363546515614813 Maletis GB, Chen J, Inacio MCS, Funahashi TT (2015) Age-related risk factors for revision anterior cruciate ligament reconstruction: a cohort study of 21,304 patients from the Kaiser Permanente Anterior Cruciate Ligament Registry. Am J Sports Med. doi:10.​1177/​0363546515614813​
15.
go back to reference Maletis GB, Granan L-P, Inacio MCS, Funahashi TT, Engebretsen L (2011) Comparison of community-based ACL reconstruction registries in the U.S. and Norway. J Bone Joint Surg Am 93(Suppl 3):31–36PubMed Maletis GB, Granan L-P, Inacio MCS, Funahashi TT, Engebretsen L (2011) Comparison of community-based ACL reconstruction registries in the U.S. and Norway. J Bone Joint Surg Am 93(Suppl 3):31–36PubMed
16.
go back to reference Maletis GB, Inacio MCS, Desmond JL, Funahashi TT (2013) Reconstruction of the anterior cruciate ligament: association of graft choice with increased risk of early revision. Bone Joint J 95:623–628CrossRefPubMed Maletis GB, Inacio MCS, Desmond JL, Funahashi TT (2013) Reconstruction of the anterior cruciate ligament: association of graft choice with increased risk of early revision. Bone Joint J 95:623–628CrossRefPubMed
17.
go back to reference Paxton EW, Namba RS, Maletis GB, Khatod M, Yue EJ, Davies M, Low RB, Wyatt RW, Inacio MC, Funahashi TT (2010) A prospective study of 80,000 total joint and 5000 anterior cruciate ligament reconstruction procedures in a community-based registry in the United States. J Bone Joint Surg Am 92(Suppl 2):117–132CrossRefPubMed Paxton EW, Namba RS, Maletis GB, Khatod M, Yue EJ, Davies M, Low RB, Wyatt RW, Inacio MC, Funahashi TT (2010) A prospective study of 80,000 total joint and 5000 anterior cruciate ligament reconstruction procedures in a community-based registry in the United States. J Bone Joint Surg Am 92(Suppl 2):117–132CrossRefPubMed
18.
go back to reference Spindler KP, Kuhn JE, Freedman KB, Matthews CE, Dittus RS, Harrell FEJ (2004) Anterior cruciate ligament reconstruction autograft choice: bone-tendon-bone versus hamstring: does it really matter? A systematic review. Am J Sports Med 32:1986–1995CrossRefPubMed Spindler KP, Kuhn JE, Freedman KB, Matthews CE, Dittus RS, Harrell FEJ (2004) Anterior cruciate ligament reconstruction autograft choice: bone-tendon-bone versus hamstring: does it really matter? A systematic review. Am J Sports Med 32:1986–1995CrossRefPubMed
Metadata
Title
A comparison of revision and rerupture rates of ACL reconstruction between autografts and allografts in the skeletally immature
Authors
Ian R. Nelson
Jason Chen
Rebecca Love
Brent R. Davis
Gregory B. Maletis
Tadashi T. Funahashi
Publication date
01-03-2016
Publisher
Springer Berlin Heidelberg
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 3/2016
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-016-4020-6

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