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Published in: Knee Surgery, Sports Traumatology, Arthroscopy 9/2017

01-09-2017 | Knee

Periarticular injections with continuous perfusion of local anaesthetics provide better pain relief and better function compared to femoral and sciatic blocks after TKA: a randomized clinical trial

Authors: A. Stathellis, W. Fitz, C. Schnurr, F. X. Koeck, M. Gebauer, J. Huth, G. Bauer, J. Beckmann

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 9/2017

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Abstract

Purpose

Combined femoral and sciatic nerve blocks for post-operative pain management following total knee arthroplasty (TKA) improve patient satisfaction, decrease narcotic consumption and improve pain. However, accompanying motoric weakness can cause falls and related complications. We wonder whether peri-capsular injections in combination with intra-articular perfusion of local anaesthetics would result in equal or less pain without the related complications of nerve blocks. The objective of the study was to verify these aspects in a prospective randomized trial comparing both treatments.

Methods

Fifty TKA patients randomly received either a femoral (continuous) and a sciatic (single-shot) nerve block (CFNB group, 25 knees) or periarticular infiltrations and a continuous post-operative intra-articular infusion (PIAC group, 25 knees). VAS for pain, pain medication consumption, functional assessment, straight leg raising as well as KSS were recorded post-operatively for 6 days.

Results

VAS (p < 0.001) and KSS (p = 0.05) were significantly better for PIAC. There was increased pain following CFNB compared to PIAC. Catheters stayed for 4 days, a pain ‘rebound’ occurred after removing in CFNB but not after PIAC. There was no difference in regard to knee function (n.s.), but straight leg raising was significant better following PIAC. There were two falls in patients with CFNB.

Conclusion

Peri-capsular injections combined with an intra-articular catheter provide better pain control, no rebound pain with better function and might decrease the risk of complications related to motor weakness.

Level of evidence

I.
Literature
1.
go back to reference Affas F, Nygards EB, Stiller CO, Wretenberg P, Olofsson C (2011) Pain control after total knee arthroplasty: a randomized trial comparing local infiltration anesthesia and continuous femoral block. Acta Orthop 82(4):441–447CrossRefPubMedPubMedCentral Affas F, Nygards EB, Stiller CO, Wretenberg P, Olofsson C (2011) Pain control after total knee arthroplasty: a randomized trial comparing local infiltration anesthesia and continuous femoral block. Acta Orthop 82(4):441–447CrossRefPubMedPubMedCentral
3.
go back to reference Andersen KV, Bak M, Christensen BV, Harazuk J, Pedersen NA, Soballe K (2010) A randomized, controlled trial comparing local infiltration analgesia with epidural infusion for total knee arthroplasty. Acta Orthop 81(5):606–610CrossRefPubMedPubMedCentral Andersen KV, Bak M, Christensen BV, Harazuk J, Pedersen NA, Soballe K (2010) A randomized, controlled trial comparing local infiltration analgesia with epidural infusion for total knee arthroplasty. Acta Orthop 81(5):606–610CrossRefPubMedPubMedCentral
4.
go back to reference Andersen LO, Kehlet H (2014) Analgesic efficacy of local infiltration analgesia in hip and knee arthroplasty: a systematic review. Br J Anaesth 113(3):360–374CrossRefPubMed Andersen LO, Kehlet H (2014) Analgesic efficacy of local infiltration analgesia in hip and knee arthroplasty: a systematic review. Br J Anaesth 113(3):360–374CrossRefPubMed
5.
go back to reference Bianconi M, Ferraro L, Traina GC, Zanoli G, Antonelli T, Guberti A, Ricci R, Massari L (2003) Pharmacokinetics and efficacy of ropivacaine continuous wound instillation after joint replacement surgery. Br J Anaesth 91(6):830–835CrossRefPubMed Bianconi M, Ferraro L, Traina GC, Zanoli G, Antonelli T, Guberti A, Ricci R, Massari L (2003) Pharmacokinetics and efficacy of ropivacaine continuous wound instillation after joint replacement surgery. Br J Anaesth 91(6):830–835CrossRefPubMed
6.
go back to reference Carli F, Clemente A, Asenjo JF, Kim DJ, Mistraletti G, Gomarasca M, Morabito A, Tanzer M (2010) Analgesia and functional outcome after total knee arthroplasty: periarticular infiltration vs continuous femoral nerve block. Br J Anaesth 105(2):185–195CrossRefPubMed Carli F, Clemente A, Asenjo JF, Kim DJ, Mistraletti G, Gomarasca M, Morabito A, Tanzer M (2010) Analgesia and functional outcome after total knee arthroplasty: periarticular infiltration vs continuous femoral nerve block. Br J Anaesth 105(2):185–195CrossRefPubMed
7.
go back to reference Chaumeron A, Audy D, Drolet P, Lavigne M, Vendittoli PA (2013) Periarticular injection in knee arthroplasty improves quadriceps function. Clin Orthop Relat Res 471(7):2284–2295CrossRefPubMedPubMedCentral Chaumeron A, Audy D, Drolet P, Lavigne M, Vendittoli PA (2013) Periarticular injection in knee arthroplasty improves quadriceps function. Clin Orthop Relat Res 471(7):2284–2295CrossRefPubMedPubMedCentral
9.
go back to reference Fu H, Wang J, Zhang W, Cheng T, Zhang X (2015) Potential superiority of periarticular injection in analgesic effect and early mobilization ability over femoral nerve block following total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. doi:10.1007/s00167-015-3519-6 Fu H, Wang J, Zhang W, Cheng T, Zhang X (2015) Potential superiority of periarticular injection in analgesic effect and early mobilization ability over femoral nerve block following total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. doi:10.​1007/​s00167-015-3519-6
10.
go back to reference Goyal N, McKenzie J, Sharkey PF, Parvizi J, Hozack WJ, Austin MS (2013) The 2012 Chitranjan Ranawat award: intraarticular analgesia after TKA reduces pain: a randomized, double-blinded, placebo-controlled, prospective study. Clin Orthop Relat Res 471(1):64–75CrossRefPubMed Goyal N, McKenzie J, Sharkey PF, Parvizi J, Hozack WJ, Austin MS (2013) The 2012 Chitranjan Ranawat award: intraarticular analgesia after TKA reduces pain: a randomized, double-blinded, placebo-controlled, prospective study. Clin Orthop Relat Res 471(1):64–75CrossRefPubMed
11.
go back to reference Hadzic A, Houle TT, Capdevila X, Ilfeld BM (2010) Femoral nerve block for analgesia in patients having knee arthroplasty. Anesthesiology 113(5):1014–1015CrossRefPubMed Hadzic A, Houle TT, Capdevila X, Ilfeld BM (2010) Femoral nerve block for analgesia in patients having knee arthroplasty. Anesthesiology 113(5):1014–1015CrossRefPubMed
12.
go back to reference Kim TW, Park SJ, Lim SH, Seong SC, Lee S, Lee MC (2015) Which analgesic mixture is appropriate for periarticular injection after total knee arthroplasty? Prospective, randomized, double-blind study. Knee Surg Sports Traumatol Arthrosc 23(3):838–845CrossRefPubMed Kim TW, Park SJ, Lim SH, Seong SC, Lee S, Lee MC (2015) Which analgesic mixture is appropriate for periarticular injection after total knee arthroplasty? Prospective, randomized, double-blind study. Knee Surg Sports Traumatol Arthrosc 23(3):838–845CrossRefPubMed
13.
go back to reference Korean Knee S (2012) Guidelines for the management of postoperative pain after total knee arthroplasty. Knee Surg Relat Res 24(4):201–207CrossRef Korean Knee S (2012) Guidelines for the management of postoperative pain after total knee arthroplasty. Knee Surg Relat Res 24(4):201–207CrossRef
14.
go back to reference Marhofer P, Harrop-Griffiths W, Kettner SC, Kirchmair L (2010) Fifteen years of ultrasound guidance in regional anaesthesia: part 1. Br J Anaesth 104(5):538–546CrossRefPubMed Marhofer P, Harrop-Griffiths W, Kettner SC, Kirchmair L (2010) Fifteen years of ultrasound guidance in regional anaesthesia: part 1. Br J Anaesth 104(5):538–546CrossRefPubMed
15.
go back to reference Marhofer P, Harrop-Griffiths W, Willschke H, Kirchmair L (2010) Fifteen years of ultrasound guidance in regional anaesthesia: part 2-recent developments in block techniques. Br J Anaesth 104(6):673–683CrossRefPubMed Marhofer P, Harrop-Griffiths W, Willschke H, Kirchmair L (2010) Fifteen years of ultrasound guidance in regional anaesthesia: part 2-recent developments in block techniques. Br J Anaesth 104(6):673–683CrossRefPubMed
16.
go back to reference McCartney CJ, McLeod GA (2011) Local infiltration analgesia for total knee arthroplasty. Br J Anaesth 107(4):487–489CrossRefPubMed McCartney CJ, McLeod GA (2011) Local infiltration analgesia for total knee arthroplasty. Br J Anaesth 107(4):487–489CrossRefPubMed
17.
go back to reference Michael JW, Schluter-Brust KU, Eysel P (2010) The epidemiology, etiology, diagnosis, and treatment of osteoarthritis of the knee. Dtsch Arztebl Int 107(9):152–162PubMedPubMedCentral Michael JW, Schluter-Brust KU, Eysel P (2010) The epidemiology, etiology, diagnosis, and treatment of osteoarthritis of the knee. Dtsch Arztebl Int 107(9):152–162PubMedPubMedCentral
18.
go back to reference Moghtadaei M, Farahini H, Faiz SH, Mokarami F, Safari S (2014) Pain management for total knee arthroplasty: single-injection femoral nerve block versus local infiltration analgesia. Iran Red Crescent Med J 16(1):e13247CrossRefPubMedPubMedCentral Moghtadaei M, Farahini H, Faiz SH, Mokarami F, Safari S (2014) Pain management for total knee arthroplasty: single-injection femoral nerve block versus local infiltration analgesia. Iran Red Crescent Med J 16(1):e13247CrossRefPubMedPubMedCentral
19.
go back to reference Nakai T, Tamaki M, Nakamura T, Nakai T, Onishi A, Hashimoto K (2013) Controlling pain after total knee arthroplasty using a multimodal protocol with local periarticular injections. J Orthop 10(2):92–94CrossRefPubMedPubMedCentral Nakai T, Tamaki M, Nakamura T, Nakai T, Onishi A, Hashimoto K (2013) Controlling pain after total knee arthroplasty using a multimodal protocol with local periarticular injections. J Orthop 10(2):92–94CrossRefPubMedPubMedCentral
20.
go back to reference Niemelainen M, Kalliovalkama J, Aho AJ, Moilanen T, Eskelinen A (2014) Single periarticular local infiltration analgesia reduces opiate consumption until 48 hours after total knee arthroplasty. A randomized placebo-controlled trial involving 56 patients. Acta Orthop 85(6):614–619CrossRefPubMedPubMedCentral Niemelainen M, Kalliovalkama J, Aho AJ, Moilanen T, Eskelinen A (2014) Single periarticular local infiltration analgesia reduces opiate consumption until 48 hours after total knee arthroplasty. A randomized placebo-controlled trial involving 56 patients. Acta Orthop 85(6):614–619CrossRefPubMedPubMedCentral
21.
go back to reference Ong JC, Chin PL, Fook-Chong SM, Tang A, Yang KY, Tay BK (2010) Continuous infiltration of local anaesthetic following total knee arthroplasty. J Orthop Surg (Hong Kong) 18(2):203–207CrossRef Ong JC, Chin PL, Fook-Chong SM, Tang A, Yang KY, Tay BK (2010) Continuous infiltration of local anaesthetic following total knee arthroplasty. J Orthop Surg (Hong Kong) 18(2):203–207CrossRef
22.
go back to reference Paul JE, Arya A, Hurlburt L, Cheng J, Thabane L, Tidy A, Murthy Y (2010) Femoral nerve block improves analgesia outcomes after total knee arthroplasty: a meta-analysis of randomized controlled trials. Anesthesiology 113(5):1144–1162CrossRefPubMed Paul JE, Arya A, Hurlburt L, Cheng J, Thabane L, Tidy A, Murthy Y (2010) Femoral nerve block improves analgesia outcomes after total knee arthroplasty: a meta-analysis of randomized controlled trials. Anesthesiology 113(5):1144–1162CrossRefPubMed
23.
go back to reference Reinhardt KR, Duggal S, Umunna BP, Reinhardt GA, Nam D, Alexiades M, Cornell CN (2014) Intraarticular analgesia versus epidural plus femoral nerve block after TKA: a randomized, double-blind trial. Clin Orthop Relat Res 472(5):1400–1408CrossRefPubMed Reinhardt KR, Duggal S, Umunna BP, Reinhardt GA, Nam D, Alexiades M, Cornell CN (2014) Intraarticular analgesia versus epidural plus femoral nerve block after TKA: a randomized, double-blind trial. Clin Orthop Relat Res 472(5):1400–1408CrossRefPubMed
24.
go back to reference Sharma S, Iorio R, Specht LM, Davies-Lepie S, Healy WL (2010) Complications of femoral nerve block for total knee arthroplasty. Clin Orthop Relat Res 468(1):135–140CrossRefPubMed Sharma S, Iorio R, Specht LM, Davies-Lepie S, Healy WL (2010) Complications of femoral nerve block for total knee arthroplasty. Clin Orthop Relat Res 468(1):135–140CrossRefPubMed
25.
go back to reference Spangehl MJ, Clarke HD, Hentz JG, Misra L, Blocher JL, Seamans DP (2015) The Chitranjan Ranawat Award: periarticular injections and femoral & sciatic blocks provide similar pain relief after TKA: a randomized clinical trial. Clin Orthop Relat Res 473(1):45–53CrossRefPubMed Spangehl MJ, Clarke HD, Hentz JG, Misra L, Blocher JL, Seamans DP (2015) The Chitranjan Ranawat Award: periarticular injections and femoral & sciatic blocks provide similar pain relief after TKA: a randomized clinical trial. Clin Orthop Relat Res 473(1):45–53CrossRefPubMed
26.
go back to reference Szucs S, Morau D, Iohom G (2010) Femoral nerve blockade. Med Ultrason 12(2):139–144PubMed Szucs S, Morau D, Iohom G (2010) Femoral nerve blockade. Med Ultrason 12(2):139–144PubMed
27.
go back to reference Teng Y, Jiang J, Chen S, Zhao L, Cui Z, Khan MS, Du W, Gao X, Wang J, Xia Y (2014) Periarticular multimodal drug injection in total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 22(8):1949–1957CrossRefPubMed Teng Y, Jiang J, Chen S, Zhao L, Cui Z, Khan MS, Du W, Gao X, Wang J, Xia Y (2014) Periarticular multimodal drug injection in total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 22(8):1949–1957CrossRefPubMed
28.
go back to reference Toftdahl K, Nikolajsen L, Haraldsted V, Madsen F, Tonnesen EK, Soballe K (2007) Comparison of peri- and intraarticular analgesia with femoral nerve block after total knee arthroplasty: a randomized clinical trial. Acta Orthop 78(2):172–179CrossRefPubMed Toftdahl K, Nikolajsen L, Haraldsted V, Madsen F, Tonnesen EK, Soballe K (2007) Comparison of peri- and intraarticular analgesia with femoral nerve block after total knee arthroplasty: a randomized clinical trial. Acta Orthop 78(2):172–179CrossRefPubMed
29.
go back to reference Uesugi K, Kitano N, Kikuchi T, Sekiguchi M, Konno S (2014) Comparison of peripheral nerve block with periarticular injection analgesia after total knee arthroplasty: a randomized, controlled study. Knee 21(4):848–852CrossRefPubMed Uesugi K, Kitano N, Kikuchi T, Sekiguchi M, Konno S (2014) Comparison of peripheral nerve block with periarticular injection analgesia after total knee arthroplasty: a randomized, controlled study. Knee 21(4):848–852CrossRefPubMed
30.
go back to reference Van Manen MD, Nace J, Mont MA (2012) Management of primary knee osteoarthritis and indications for total knee arthroplasty for general practitioners. J Am Osteopath Assoc 112(11):709–715PubMed Van Manen MD, Nace J, Mont MA (2012) Management of primary knee osteoarthritis and indications for total knee arthroplasty for general practitioners. J Am Osteopath Assoc 112(11):709–715PubMed
31.
go back to reference Yadeau JT, Goytizolo EA, Padgett DE, Liu SS, Mayman DJ, Ranawat AS, Rade MC, Westrich GH (2013) Analgesia after total knee replacement: local infiltration versus epidural combined with a femoral nerve blockade: a prospective, randomised pragmatic trial. Bone Joint J 95-B(5):629–635CrossRefPubMed Yadeau JT, Goytizolo EA, Padgett DE, Liu SS, Mayman DJ, Ranawat AS, Rade MC, Westrich GH (2013) Analgesia after total knee replacement: local infiltration versus epidural combined with a femoral nerve blockade: a prospective, randomised pragmatic trial. Bone Joint J 95-B(5):629–635CrossRefPubMed
32.
go back to reference Yuenyongviwat V, Pornrattanamaneewong C, Chinachoti T, Chareancholvanich K (2012) Periarticular injection with bupivacaine for postoperative pain control in total knee replacement: a prospective randomized double-blind controlled trial. Adv Orthop 2012:107309CrossRefPubMedPubMedCentral Yuenyongviwat V, Pornrattanamaneewong C, Chinachoti T, Chareancholvanich K (2012) Periarticular injection with bupivacaine for postoperative pain control in total knee replacement: a prospective randomized double-blind controlled trial. Adv Orthop 2012:107309CrossRefPubMedPubMedCentral
Metadata
Title
Periarticular injections with continuous perfusion of local anaesthetics provide better pain relief and better function compared to femoral and sciatic blocks after TKA: a randomized clinical trial
Authors
A. Stathellis
W. Fitz
C. Schnurr
F. X. Koeck
M. Gebauer
J. Huth
G. Bauer
J. Beckmann
Publication date
01-09-2017
Publisher
Springer Berlin Heidelberg
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 9/2017
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-015-3633-5

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