Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Knee Surgery, Sports Traumatology, Arthroscopy
Published in: Knee Surgery, Sports Traumatology, Arthroscopy 2/2012

01-02-2012 | Editorial

See the whole picture: knee preserving therapy needs more than surface repair

Authors: Markus P. Arnold, Michael T. Hirschmann, Peter C. M. Verdonk

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 2/2012

Login to get access

Excerpt

After years of stagnation in orthopaedic surgery the advancements in cartilage research will soon lead to a real paradigm shift of diagnostics and treatment. Great progress has been made over the last decades to get cartilage repair procedures from bench to clinical practice. Instead of replacing injured cartilage using metal and polyethylene-implants it is often possible to biologically reconstruct cartilage lesions, even when several pathologies have to be addressed. The scientific basis that has been built up is unparalleled by any introduction of innovations before [5, 7, 9]. …
Literature
1.
Barbero A, Grogan S, Schafer D, Heberer M, Mainil-Varlet P, Martin I (2004) Age related changes in human articular chondrocyte yield, proliferation and post-expansion chondrogenic capacity. Osteoarthr Cartil 12(6):476–484PubMedCrossRef
2.
Bekkers JE, Inklaar M, Saris DB (2009) Treatment selection in articular cartilage lesions of the knee: a systematic review. Am J Sports Med 37(Suppl 1):148S–155SPubMedCrossRef
3.
Dye SF (1996) The knee as a biologic transmission with an envelope of function: a theory. Clin Orthop Relat Res 325:10–18PubMedCrossRef
4.
Fitzgerald SJ, Trousdale RT (2011) Why knees fail in 2011: patient, surgeon, or device? Orthopedics 34(9):e513–e515PubMed
5.
Minas T, Gomoll AH, Solhpour S, Rosenberger R, Probst C, Bryant T (2010) Autologous chondrocyte implantation for joint preservation in patients with early osteoarthritis. Clin Orthop Relat Res 468(1):147–157PubMedCrossRef
6.
Nilsdotter AK, Toksvig-Larsen S, Roos EM (2009) Knee arthroplasty: are patients’ expectations fulfilled? A prospective study of pain and function in 102 patients with 5-year follow-up. Acta Orthop 80(1):55–61PubMedCrossRef
7.
Peterson L, Vasiliadis HS, Brittberg M, Lindahl A (2010) Autologous Chondrocyte Implantation: A Long-term Follow-up. Am J Sports Med 38:1117–1124
8.
Saris DB, Dhert WJ, Verbout AJ (2003) Joint homeostasis. The discrepancy between old and fresh defects in cartilage repair. J Bone Joint Surg Br 85(7):1067–1076PubMedCrossRef
9.
Saris DB, Vanlauwe J, Victor J, Almqvist KF, Verdonk R, Bellemans J, Luyten FP (2009) Treatment of symptomatic cartilage defects of the knee: characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial compared to microfracture. Am J Sports Med 37(Suppl 1):10S–19SPubMedCrossRef
10.
Shelbourne KD (2010) The art of the knee examination: where has it gone? J Bone Joint Surg Am 92(9):e9PubMedCrossRef
11.
Slauterbeck JR, Kousa P, Clifton BC, Naud S, Tourville TW, Johnson RJ, Beynnon BD (2009) Geographic mapping of meniscus and cartilage lesions associated with anterior cruciate ligament injuries. J Bone Joint Surg Am 91(9):2094–2103PubMedCrossRef
Metadata
Title
See the whole picture: knee preserving therapy needs more than surface repair
Authors
Markus P. Arnold
Michael T. Hirschmann
Peter C. M. Verdonk
Publication date
01-02-2012
Publisher
Springer-Verlag
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 2/2012
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-011-1733-4

Other articles of this Issue 2/2012

Knee Surgery, Sports Traumatology, Arthroscopy 2/2012 Go to the issue

Experimental Study

Fibrin glue does not improve the fixation of press-fitted cell-free collagen gel plugs in an ex vivo cartilage repair model

Knee

Refixation after lateral meniscus tear followed by complete luxation in an 11-year-old

Knee

Cryopreservation increases apoptosis in human menisci

Knee

Aperture fixation instead of transverse tunnels at the patella for medial patellofemoral ligament reconstruction

Knee

The role of the medial ligamentous structures on patellar tracking during knee flexion

Shoulder

Conventional rotator cuff repair complemented by the aid of mononuclear autologous stem cells