Skip to main content
Top
Published in: Knee Surgery, Sports Traumatology, Arthroscopy 3/2011

01-03-2011 | Knee

May smokers and overweight patients be treated with a medial open-wedge HTO? Risk factors for non-union

Authors: Gebhart Meidinger, Andreas B. Imhoff, Jochen Paul, Chlodwig Kirchhoff, Martin Sauerschnig, Stefan Hinterwimmer

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 3/2011

Login to get access

Abstract

Purpose

The purpose of this retrospective study was to investigate the rate of non-union after medial open-wedge high tibial osteotomy (HTO) with the Tomofix® plate. In addition, risk factors with a possible influence on the development of a non-union were analysed.

Methods

Between 2006 and 2008, a total of 186 medial open-wedge HTOs were performed in 182 patients.

Results

Ten cases of non-union (5.4%) were recorded. Risk factors with a statistically significant influence on the development of a non-union included smoking, body mass index and fracture of the lateral cortical hinge. No influence was detected for the factors age, degree of correction, concomitant diseases, postoperative complications, drug use, additionally performed procedures and use of a temporary lag screw.

Conclusion

Within this study, it could be demonstrated that the rate of non-union in medial open-wedge HTO is not higher than in the lateral closed-wedge technique. Concerning the detected risk factors, the importance of the preservation of the lateral cortex is emphasised. In addition, it is necessary to discuss the risk of non-union with smokers and overweight patients when planning the therapy. Finally, it should be considered to perform iliac crest bone grafting in these high-risk patients a priori.

Level of evidence

IV.
Literature
1.
go back to reference Amendola A, Bonasia DE (2010) Results of high tibial osteotomy: review of the literature. Int Orthop 34:155–160CrossRefPubMed Amendola A, Bonasia DE (2010) Results of high tibial osteotomy: review of the literature. Int Orthop 34:155–160CrossRefPubMed
2.
go back to reference Aydogdu S, Cullu E, Arac N et al (2000) Prolonged peroneal nerve dysfunction after high tibial osteotomy: pre- and postoperative electrophysiological study. Knee Surg Sports Traumatol Arthrosc 8:305–308CrossRefPubMed Aydogdu S, Cullu E, Arac N et al (2000) Prolonged peroneal nerve dysfunction after high tibial osteotomy: pre- and postoperative electrophysiological study. Knee Surg Sports Traumatol Arthrosc 8:305–308CrossRefPubMed
3.
go back to reference Brown CW, Orme TJ, Richardson HD (1986) The rate of pseudarthrosis (surgical nonunion) in patients who are smokers and patients who are nonsmokers: a comparison study. Spine (Phila Pa 1976) 11:942–943 Brown CW, Orme TJ, Richardson HD (1986) The rate of pseudarthrosis (surgical nonunion) in patients who are smokers and patients who are nonsmokers: a comparison study. Spine (Phila Pa 1976) 11:942–943
4.
go back to reference Cameron HU, Welsh RP, Jung YB, Noftall F (1993) Repair of nonunion of tibial osteotomy. Clin Orthop Relat Res 278:167–169 Cameron HU, Welsh RP, Jung YB, Noftall F (1993) Repair of nonunion of tibial osteotomy. Clin Orthop Relat Res 278:167–169
5.
go back to reference Cobb TK, Gabrielsen TA, Campbell DC 2nd et al (1994) Cigarette smoking and nonunion after ankle arthrodesis. Foot Ankle Int 15:64–67PubMed Cobb TK, Gabrielsen TA, Campbell DC 2nd et al (1994) Cigarette smoking and nonunion after ankle arthrodesis. Foot Ankle Int 15:64–67PubMed
6.
go back to reference Coventry MB (1984) Upper tibial osteotomy. Clin Orthop Relat Res 182:46–52PubMed Coventry MB (1984) Upper tibial osteotomy. Clin Orthop Relat Res 182:46–52PubMed
7.
go back to reference Coventry MB, Ilstrup DM, Wallrichs SL (1993) Proximal tibial osteotomy. A critical long-term study of eighty-seven cases. J Bone Joint Surg Am 75:196–201PubMed Coventry MB, Ilstrup DM, Wallrichs SL (1993) Proximal tibial osteotomy. A critical long-term study of eighty-seven cases. J Bone Joint Surg Am 75:196–201PubMed
8.
go back to reference Gaasbeek RD, Welsing RT, Verdonschot N et al (2005) Accuracy and initial stability of open- and closed-wedge high tibial osteotomy: a cadaveric RSA study. Knee Surg Sports Traumatol Arthrosc 13:689–694CrossRefPubMed Gaasbeek RD, Welsing RT, Verdonschot N et al (2005) Accuracy and initial stability of open- and closed-wedge high tibial osteotomy: a cadaveric RSA study. Knee Surg Sports Traumatol Arthrosc 13:689–694CrossRefPubMed
9.
go back to reference Galla M, Lobenhoffer P, Staubli AE (2006) Die valgisierende öffnende Umstellungsosteotomie der proximalen Tibia mit Plattenfixateur. In: Lobenhoffer P, Agneskirchner JD, Galla M (eds) Kniegelenknahe Osteotomien. Indikation, Planung, Operationstechnik mit Plattenfixateuren. Thieme, Stuttgart, pp 51–64 Galla M, Lobenhoffer P, Staubli AE (2006) Die valgisierende öffnende Umstellungsosteotomie der proximalen Tibia mit Plattenfixateur. In: Lobenhoffer P, Agneskirchner JD, Galla M (eds) Kniegelenknahe Osteotomien. Indikation, Planung, Operationstechnik mit Plattenfixateuren. Thieme, Stuttgart, pp 51–64
10.
go back to reference Green E, Lubahn JD, Evans J (2005) Risk factors, treatment, and outcomes associated with nonunion of the midshaft humerus fracture. J Surg Orthop Adv 14:64–72PubMed Green E, Lubahn JD, Evans J (2005) Risk factors, treatment, and outcomes associated with nonunion of the midshaft humerus fracture. J Surg Orthop Adv 14:64–72PubMed
11.
go back to reference Hernigou P, Ma W (2001) Open wedge tibial osteotomy with acrylic bone cement as bone substitute. Knee 8:103–110CrossRefPubMed Hernigou P, Ma W (2001) Open wedge tibial osteotomy with acrylic bone cement as bone substitute. Knee 8:103–110CrossRefPubMed
12.
go back to reference Hoogendoorn JM, Simmermacher RK, Schellekens PP, van der Werken C (2002) Rauchen ist nachteilig für die Heilung von Knochen und Weichteilen. Unfallchirurg 105:76–81CrossRefPubMed Hoogendoorn JM, Simmermacher RK, Schellekens PP, van der Werken C (2002) Rauchen ist nachteilig für die Heilung von Knochen und Weichteilen. Unfallchirurg 105:76–81CrossRefPubMed
13.
go back to reference Hunt N, Watts M, Hayes D et al (2005) Closing wedge high tibial osteotomy: review of 374 cases. J Bone Joint Surg Br 87-B:346 Hunt N, Watts M, Hayes D et al (2005) Closing wedge high tibial osteotomy: review of 374 cases. J Bone Joint Surg Br 87-B:346
15.
go back to reference Lee C, Dorcil J, Radomisli TE (2004) Nonunion of the spine: a review. Clin Orthop Relat Res 419:71–75CrossRefPubMed Lee C, Dorcil J, Radomisli TE (2004) Nonunion of the spine: a review. Clin Orthop Relat Res 419:71–75CrossRefPubMed
16.
go back to reference Lobenhoffer P, Agneskirchner JD (2003) Improvements in surgical technique of valgus high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 11:132–138PubMed Lobenhoffer P, Agneskirchner JD (2003) Improvements in surgical technique of valgus high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 11:132–138PubMed
17.
go back to reference Lobenhoffer P, Agneskirchner J, Zoch W (2004) Die öffnende valgisierende Osteotomie der proximalen Tibia mit Fixation durch einen medialen Plattenfixateur. Orthopade 33:153–160CrossRefPubMed Lobenhoffer P, Agneskirchner J, Zoch W (2004) Die öffnende valgisierende Osteotomie der proximalen Tibia mit Fixation durch einen medialen Plattenfixateur. Orthopade 33:153–160CrossRefPubMed
18.
go back to reference Lobenhoffer P (2009) Die öffnende Tibiakopfosteotomie zur Behandlung der monokompartimentalen Gonarthrose. Arthroskopie 22:223–231CrossRef Lobenhoffer P (2009) Die öffnende Tibiakopfosteotomie zur Behandlung der monokompartimentalen Gonarthrose. Arthroskopie 22:223–231CrossRef
19.
go back to reference Miller BS, Dorsey WO, Bryant CR, Austin JC (2005) The effect of lateral cortex disruption and repair on the stability of the medial opening wedge high tibial osteotomy. Am J Sports Med 33:1552–1557CrossRefPubMed Miller BS, Dorsey WO, Bryant CR, Austin JC (2005) The effect of lateral cortex disruption and repair on the stability of the medial opening wedge high tibial osteotomy. Am J Sports Med 33:1552–1557CrossRefPubMed
20.
go back to reference Miller BS, Downie B, McDonough EB, Wojtys EM (2009) Complications after medial opening wedge high tibial osteotomy. Arthroscopy 25:639–646CrossRefPubMed Miller BS, Downie B, McDonough EB, Wojtys EM (2009) Complications after medial opening wedge high tibial osteotomy. Arthroscopy 25:639–646CrossRefPubMed
21.
go back to reference Naudie D, Bourne RB, Rorabeck CH, Bourne TJ (1999) The Install Award. Survivorship of the high tibial valgus osteotomy. A 10- to -22-year followup study. Clin Orthop Relat Res 367:18–27CrossRefPubMed Naudie D, Bourne RB, Rorabeck CH, Bourne TJ (1999) The Install Award. Survivorship of the high tibial valgus osteotomy. A 10- to -22-year followup study. Clin Orthop Relat Res 367:18–27CrossRefPubMed
22.
go back to reference Noyes FR, Mayfield W, Barber-Westin SD et al (2006) Opening wedge high tibial osteotomy: an operative technique and rehabilitation program to decrease complications and promote early union and function. Am J Sports Med 34:1262–1273CrossRefPubMed Noyes FR, Mayfield W, Barber-Westin SD et al (2006) Opening wedge high tibial osteotomy: an operative technique and rehabilitation program to decrease complications and promote early union and function. Am J Sports Med 34:1262–1273CrossRefPubMed
23.
go back to reference Pape D, Adam F, Rupp S et al (2004) Stabilität, Knochenheilung und Korrekturverlust nach valgisierender Tibiakopfumstellung. Eine Röntgenstereometrieanalyse. Orthopäde 33:208–217CrossRefPubMed Pape D, Adam F, Rupp S et al (2004) Stabilität, Knochenheilung und Korrekturverlust nach valgisierender Tibiakopfumstellung. Eine Röntgenstereometrieanalyse. Orthopäde 33:208–217CrossRefPubMed
24.
go back to reference Reischl N, Wahl P, Jacobi M et al (2009) Infections after high tibial open wedge osteotomy: a case control study. Arch Orthop Trauma Surg 129:1483–1487CrossRefPubMed Reischl N, Wahl P, Jacobi M et al (2009) Infections after high tibial open wedge osteotomy: a case control study. Arch Orthop Trauma Surg 129:1483–1487CrossRefPubMed
25.
go back to reference Rodriguez-Merchan EC, Forriol F (2004) Nonunion: general principles and experimental data. Clin Orthop Relat Res 419:4–12CrossRefPubMed Rodriguez-Merchan EC, Forriol F (2004) Nonunion: general principles and experimental data. Clin Orthop Relat Res 419:4–12CrossRefPubMed
27.
go back to reference Seide K, Wenzl ME, Wolter D, Jürgens C (2001) Posttraumatische Pseudarthrosen und Fehlstellungen des distalen Unterschenkels. Trauma und Berufskrankheit 4:301–304CrossRef Seide K, Wenzl ME, Wolter D, Jürgens C (2001) Posttraumatische Pseudarthrosen und Fehlstellungen des distalen Unterschenkels. Trauma und Berufskrankheit 4:301–304CrossRef
28.
go back to reference Spahn G (2004) Complications in high tibial (medial opening wedge) osteotomy. Arch Orthop Trauma Surg 124:649–653CrossRefPubMed Spahn G (2004) Complications in high tibial (medial opening wedge) osteotomy. Arch Orthop Trauma Surg 124:649–653CrossRefPubMed
29.
go back to reference Sprenger TR, Doerzbacher JF (2003) Tibial osteotomy for the treatment of varus gonarthrosis. Survival and failure analysis to 22 years. J Bone Joint Surg Am 85-A:469–474PubMed Sprenger TR, Doerzbacher JF (2003) Tibial osteotomy for the treatment of varus gonarthrosis. Survival and failure analysis to 22 years. J Bone Joint Surg Am 85-A:469–474PubMed
30.
go back to reference Staubli AE, De Simoni C, Babst R, Lobenhoffer P (2003) TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia–early results in 92 cases. Injury 34(Suppl 2):B55–B62CrossRefPubMed Staubli AE, De Simoni C, Babst R, Lobenhoffer P (2003) TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia–early results in 92 cases. Injury 34(Suppl 2):B55–B62CrossRefPubMed
31.
go back to reference Takeuchi R, Ishikawa H, Aratake M et al (2009) Medial opening wedge high tibial osteotomy with early full weight bearing. Arthroscopy 25:46–53CrossRefPubMed Takeuchi R, Ishikawa H, Aratake M et al (2009) Medial opening wedge high tibial osteotomy with early full weight bearing. Arthroscopy 25:46–53CrossRefPubMed
32.
go back to reference Tjornstrand B, Hagstedt B, Persson BM (1978) Results of surgical treatment for non-union after high tibial osteotomy in osteoarthritis of the knee. J Bone Joint Surg Am 60:973–977PubMed Tjornstrand B, Hagstedt B, Persson BM (1978) Results of surgical treatment for non-union after high tibial osteotomy in osteoarthritis of the knee. J Bone Joint Surg Am 60:973–977PubMed
33.
go back to reference Tunggal JA, Higgins GA, Waddell JP (2010) Complications of closing wedge high tibial osteotomy. Int Orthop 34:255–261CrossRefPubMed Tunggal JA, Higgins GA, Waddell JP (2010) Complications of closing wedge high tibial osteotomy. Int Orthop 34:255–261CrossRefPubMed
34.
go back to reference Valkering KP, van den Bekerom MP, Kappelhoff FM, Albers GH (2009) Complications after tomofix medial opening wedge high tibial osteotomy. J Knee Surg 22:218–225CrossRefPubMed Valkering KP, van den Bekerom MP, Kappelhoff FM, Albers GH (2009) Complications after tomofix medial opening wedge high tibial osteotomy. J Knee Surg 22:218–225CrossRefPubMed
35.
go back to reference van den Bekerom MP, Patt TW, Kleinhout MY et al (2008) Early complications after high tibial osteotomy: a comparison of two techniques. J Knee Surg 21:68–74PubMed van den Bekerom MP, Patt TW, Kleinhout MY et al (2008) Early complications after high tibial osteotomy: a comparison of two techniques. J Knee Surg 21:68–74PubMed
36.
go back to reference Warden SJ, Morris HG, Crossley KM et al (2005) Delayed- and non-union following opening wedge high tibial osteotomy: surgeons’ results from 182 completed cases. Knee Surg Sports Traumatol Arthrosc 13:34–37CrossRefPubMed Warden SJ, Morris HG, Crossley KM et al (2005) Delayed- and non-union following opening wedge high tibial osteotomy: surgeons’ results from 182 completed cases. Knee Surg Sports Traumatol Arthrosc 13:34–37CrossRefPubMed
37.
go back to reference World Health Organisation (2000) WHO consultation on obesity. Obesity: preventing and managing the global epidemic. Geneva, Switzerland: WHO Technical Report Series 894 World Health Organisation (2000) WHO consultation on obesity. Obesity: preventing and managing the global epidemic. Geneva, Switzerland: WHO Technical Report Series 894
38.
go back to reference Yacobucci GN, Cocking MR (2008) Union of medial opening-wedge high tibial osteotomy using a corticocancellous proximal tibial wedge allograft. Am J Sports Med 36:713–719CrossRefPubMed Yacobucci GN, Cocking MR (2008) Union of medial opening-wedge high tibial osteotomy using a corticocancellous proximal tibial wedge allograft. Am J Sports Med 36:713–719CrossRefPubMed
Metadata
Title
May smokers and overweight patients be treated with a medial open-wedge HTO? Risk factors for non-union
Authors
Gebhart Meidinger
Andreas B. Imhoff
Jochen Paul
Chlodwig Kirchhoff
Martin Sauerschnig
Stefan Hinterwimmer
Publication date
01-03-2011
Publisher
Springer-Verlag
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 3/2011
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-010-1335-6

Other articles of this Issue 3/2011

Knee Surgery, Sports Traumatology, Arthroscopy 3/2011 Go to the issue