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Intensive Care Medicine
Published in: Intensive Care Medicine 5/2020

01-05-2020 | Coronavirus | What's New in Intensive Care

COVID-19: a novel coronavirus and a novel challenge for critical care

Authors: Yaseen M. Arabi, Srinivas Murthy, Steve Webb

Published in: Intensive Care Medicine | Issue 5/2020

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Excerpt

In December 2019, several cases of pneumonia of unknown etiology were reported in Wuhan, Hubei Province, China, and were linked to Huanan Seafood Wholesale Market [1‐3]. The disease which is now called COVID-19 is caused by a novel coronavirus, labeled as SARS-CoV-2, which was discovered through whole-genome sequencing, polymerase chain reaction (PCR) and culture of bronchoalveolar lavage fluid obtained from affected patients [1, 4]. This virus, which is the seventh coronavirus that has been proven to infect humans, has 75–80% genomic similarity to the severe acute respiratory syndrome coronavirus (SARS-CoV), 50% to the Middle East Respiratory syndrome coronavirus (MERS-CoV) and 96% to a bat coronavirus and uses the same cell receptor, angiotensin-converting enzyme II (ACE2), that is used by SARS-CoV [1, 4, 5]. …
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Metadata
Title
COVID-19: a novel coronavirus and a novel challenge for critical care
Authors
Yaseen M. Arabi
Srinivas Murthy
Steve Webb
Publication date
01-05-2020
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 5/2020
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-020-05955-1

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