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01-07-2018 | Editorial

Angiotensin inhibition in patients with acute kidney injury: Dr. Jekyll or Mr. Hyde?

Authors: Michael Joannidis, Eric Hoste

Published in: Intensive Care Medicine | Issue 7/2018

Excerpt

Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are among the most frequently applied antihypertensive drugs. Their beneficial pleiotropic effects go far beyond blood pressure reduction. Remodeling of myocardium enhances the effects of afterload reduction for the heart and makes ACEIs/ARBs a key drug in treatment of chronic heart failure as well as for secondary prevention after acute myocardial infarction. With regard to the kidney, ACEIs/ARBs have demonstrated to reduce proteinuria and slow progression of CKD [1]. …

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Title: Angiotensin inhibition in patients with acute kidney injury: Dr. Jekyll or Mr. Hyde?
Authors: Michael Joannidis
Eric Hoste
Publication date: 01-07-2018
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 7/2018
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-018-5223-8

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