Published in:
01-12-2018 | What's New in Intensive Care
Chlorhexidine use in adult patients on ICU
Authors:
Lila Bouadma, Tarja Karpanen, Tom Elliott
Published in:
Intensive Care Medicine
|
Issue 12/2018
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Excerpt
Chlorhexidine (CHG) is a biguanide cationic antiseptic molecule, which has been incorporated into mouthwash solutions, dental gels, dressings, washcloths and central venous catheters (CVC). It has become the first-choice antiseptic to reduce healthcare-associated infections. However, the widespread use of CHG has raised concerns about increasing rates of resistance and cross-resistance to antibiotics. In this short review the antimicrobial characteristics of CHG including microbial resistance and its main clinical applications in ICU are presented. …