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01-04-2018 | What's New in Intensive Care

Adjuvant therapies in critical care: steroids in community-acquired pneumonia

Authors: Antoni Torres, Miquel Ferrer, Michael S. Niederman

Published in: Intensive Care Medicine | Issue 4/2018

Excerpt

Severe community-acquired pneumonia (CAP) is present in up to 19% of hospitalized patients with CAP and still carries a high morbidity and mortality. A French multicentre study of severe pneumococcal CAP patients admitted to intensive care units (ICU) reported an overall mortality rate of 29% [1]. The high mortality of severe CAP occurs despite the fact that the majority of patients receive an early and adequate antibiotic treatment. This is probably due, in part, to an imbalanced and disproportionate local and systemic inflammatory response that contributes to impairment of gas exchange, sepsis and end-organ dysfunction. …

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Title: Adjuvant therapies in critical care: steroids in community-acquired pneumonia
Authors: Antoni Torres
Miquel Ferrer
Michael S. Niederman
Publication date: 01-04-2018
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 4/2018
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-017-4967-x

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