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01-12-2017 | Editorial

A critical view on primary and secondary outcome measures in nutrition trials

Authors: Yaseen M. Arabi, Jean-Charles Preiser

Published in: Intensive Care Medicine | Issue 12/2017

Excerpt

In this issue of Intensive Care Medicine, Allingstrup et al. report the results of the EAT-ICU trial. In this single-center study, mechanically ventilated ICU patients were randomized to early goal-directed nutrition (guided by indirect calorimetry and 24-h urinary urea measurements) versus standard of care [1]. The primary outcome of the study was the physical component summary score of SF-36 at 6 months. Secondary outcomes included mortality, rates of organ failures, serious adverse reactions, infections in the ICU, length of ICU or hospital stay, and days alive without life support at 90 days. Primary and secondary outcomes did not differ between the intervention and control groups. …

Allingstrup et al. Early goal-directed nutrition versus standard of care in adult intensive care patients: the single-centre, randomised, outcome assessor-blinded EAT-ICU trial. ICM accepted

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Title: A critical view on primary and secondary outcome measures in nutrition trials
Authors: Yaseen M. Arabi
Jean-Charles Preiser
Publication date: 01-12-2017
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 12/2017
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-017-4894-x

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A critical view on primary and secondary outcome measures in nutrition trials

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