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Intensive Care Medicine
Published in: Intensive Care Medicine 2/2017

01-02-2017 | Correspondence

How to compare clinical outcome of complementary modes of mechanical ventilation?

Authors: Christer Sinderby, A. Demoule, T. Similowski

Published in: Intensive Care Medicine | Issue 2/2017

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Excerpt

Neurally adjusted ventilatory assist (NAVA) was introduced clinically in 2007. NAVA was designed to improve patient–ventilator interaction and comfort, to encourage spontaneous breathing, and to allow intrinsic lung reflexes to protect against over distension [1]. All the above has been successfully demonstrated in numerous physiological studies [2]. Therefore, focus is now set towards clinical outcomes. …
Literature
1.
Sinderby C, Navalesi P, Beck J, Skrobik Y, Comtois N, Friberg S, Gottfried SB, Lindström L (1999) Neural control of mechanical ventilation in respiratory failure. Nat Med 5:1433–1436CrossRefPubMed
2.
Sinderby C, Beck J (2012) Neurally adjusted ventilatory assist. In: Tobin MJ (ed) Principles and practice of mechanical ventilation, 3rd edn, Chapter 13. McGraw Hill, New York, pp 351–375
3.
Demoule A, Clavel M, Rolland-Debord C, Perbet S, Terzi N, Kouatchet A, Wallet F, Roze H, Vargas F, Guerin C, Dellamonica J, Jaber S, Brochard L, Similowski T (2016) Neurally adjusted ventilatory assist as an alternative to pressure support ventilation in adults: a French multicentre randomized trial. Intensive Care Med 42:1723–1732. doi:10.​1007/​s00134-016-4447-8 CrossRefPubMed
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Xirouchaki N, Kondili E, Vaporidi K, Xirouchakis G, Klimathianaki M, Gavriilidis G, Alexandopoulou E, Plataki M, Alexopoulou C, Georgopoulos D (2008) Proportional assist ventilation with load-adjustable gain factors in critically ill patients: comparison with pressure support. Intensive Care Med 34:2026–2034CrossRefPubMed
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Bosma KJ, Read BA, Bahrgard Nikoo MJ, Jones PM, Priestap FA, Lewis JF (2016) A pilot randomized trial comparing weaning from mechanical ventilation on pressure support versus proportional assist ventilation. Crit Care Med 44:1098–1108CrossRefPubMed
Metadata
Title
How to compare clinical outcome of complementary modes of mechanical ventilation?
Authors
Christer Sinderby
A. Demoule
T. Similowski
Publication date
01-02-2017
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 2/2017
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-016-4647-2

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