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01-08-2016 | What's New in Intensive Care

What’s new in severe community-acquired pneumonia? Corticosteroids as adjunctive treatment to antibiotics

Authors: Antoni Torres, Miquel Ferrer

Published in: Intensive Care Medicine | Issue 8/2016

Excerpt

Severity criteria occur in up to 18 % of hospitalized patients with community-acquired pneumonia (CAP), and still carry a high morbidity and mortality. In a French multicentre study on severe pneumococcal CAP admitted to intensive care units (ICU), the overall mortality rate was 29 %, with high proportions of patients in septic shock and needing mechanical ventilation [1]. Patients with severe CAP (SCAP) might die despite an early and adequate antibiotic treatment. This is probably due, in part, to a misbalanced and disproportionate local and systemic inflammatory response that contributes to impairment of gas exchange, sepsis and end-organ dysfunction [2]. …

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13.

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14.

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Title: What’s new in severe community-acquired pneumonia? Corticosteroids as adjunctive treatment to antibiotics
Authors: Antoni Torres
Miquel Ferrer
Publication date: 01-08-2016
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 8/2016
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-015-4042-4

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