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At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
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Intensive Care Medicine
Literature
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Krag M, Perner A, Wetterslev J, Wise MP, Møller MH (2015) Trials on stress ulcer prophylaxis: finding the balance between benefit and harm. Intensive Care Med. doi:10.​1007/​s00134-015-3860-8
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Krag M, Perner A, Wetterslev J, Wise MP, Borthwick M, Bendel S, McArthur C, Cook DJ, Nielsen N, Pelosi P et al (2015) Prevalence and outcome of gastrointestinal bleeding and use of acid suppressants in acutely ill adult intensive care patients. Intensive Care Med 41(5):833–845. doi:10.​1007/​s00134-015-3725-1 PubMedCrossRef
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Eastwood GM, Litton E, Bellomo R, Bailey MJ, Festa M, Beasley RW, Young PJ (2014) Opinions and practice of stress ulcer prophylaxis in Australian and New Zealand intensive care units. Crit Care Resusc 16(3):170–174PubMed
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Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R et al (2013) Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med 39(2):165–228. doi:10.​1007/​s00134-012-2769-8 PubMedCrossRef
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Krag M, Perner A, Wetterslev J, Wise MP, Hylander Moller M (2014) Stress ulcer prophylaxis versus placebo or no prophylaxis in critically ill patients. A systematic review of randomised clinical trials with meta-analysis and trial sequential analysis. Intensive Care Med 40(1):11–22. doi:10.​1007/​s00134-013-3125-3 PubMedCrossRef
Metadata
Title
Trials on stress ulcer prophylaxis: finding the balance between benefit and harm. Response to Krag et al.
Authors
Adam M. Deane
Gordon H. Guyatt
Publication date
01-07-2015
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 7/2015
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-015-3877-z

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