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01-08-2014 | Letter

Neutropenic cancer patients with severe sepsis: need for antibiotics in the first hour

Authors: Djamel Mokart, Colombe Saillard, Antoine Sannini, Laurent Chow-Chine, Jean-Paul Brun, Marion Faucher, Jean-Louis Blache, Didier Blaise, Marc Leone

Published in: Intensive Care Medicine | Issue 8/2014

Excerpt

Dear Editor, …

Azoulay E, Mokart D, Pene F, Lambert J, Kouatchet A, Mayaux J, Vincent F, Nyunga M, Bruneel F, Laisne LM, Rabbat A, Lebert C, Perez P, Chaize M, Renault A, Meert AP, Benoit D, Hamidfar R, Jourdain M, Darmon M, Schlemmer B, Chevret S, Lemiale V (2013) Outcomes of critically ill patients with hematologic malignancies: prospective multicenter data from France and Belgium—a groupe de recherche respiratoire en reanimation onco-hematologique study. J Clin Oncol 31:2810–2818PubMedCrossRef

Mokart D, Slehofer G, Lambert J, Sannini A, Chow-Chine L, Brun JP, Berger P, Duran S, Faucher M, Blache JL, Saillard C, Vey N, Leone M (2014) De-escalation of antimicrobial treatment in neutropenic patients with severe sepsis: results from an observational study. Intensive Care Med 40:41–49PubMedCrossRef

Zahar JR, Timsit JF, Garrouste Org, Français A, Vesin A, Descorps-Declere A, Dubois Y, Souweine B, Haouache H, Goldgran-Toledano D, Allaouchiche B, Azoulay E, Adrie C (2011) Outcomes in severe sepsis and patients with septic shock: pathogen species and infection sites are not associated with mortality. Crit Care Med 39:1886–1895PubMedCrossRef

Ferrer R, Martin-Loeches I, Phillips G, Osborn TM, Townsend S, Dellinger RP, Artigas A, Schorr C, Levy MM (2014) Empiric antibiotic treatment reduces mortality in severe sepsis and septic shock from the first hour: results from a guideline-based performance improvement program. Crit Care Med. doi:10.1097/CCM.0000000000000330

Larche J, Azoulay E, Fieux F, Mesnard L, Moreau D, Thiery G, Darmon M, Le Gall JR, Schlemmer B (2003) Improved survival of critically ill cancer patients with septic shock. Intensive Care Med 29:1688–1695PubMedCrossRef

Title: Neutropenic cancer patients with severe sepsis: need for antibiotics in the first hour
Authors: Djamel Mokart
Colombe Saillard
Antoine Sannini
Laurent Chow-Chine
Jean-Paul Brun
Marion Faucher
Jean-Louis Blache
Didier Blaise
Marc Leone
Publication date: 01-08-2014
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 8/2014
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-014-3374-9

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Neutropenic cancer patients with severe sepsis: need for antibiotics in the first hour

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