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Intensive Care Medicine
Published in: Intensive Care Medicine 10/2011

01-10-2011 | Original

Optimal duration of a sustained inflation recruitment maneuver in ARDS patients

Authors: Jean-Michel Arnal, Jérémie Paquet, Marc Wysocki, Didier Demory, Stéphane Donati, Isabelle Granier, Gaëlle Corno, Jacques Durand-Gasselin

Published in: Intensive Care Medicine | Issue 10/2011

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Abstract

Purpose

To measure the dynamics of recruitment and the hemodynamic status during a sustained inflation recruitment maneuver (RM) in order to determine the optimal duration of RM in acute respiratory distress syndrome (ARDS) patients.

Methods

This prospective study was conducted in a 12-bed intensive care unit (ICU) in a general hospital. A 40 cmH2O sustained inflation RM maintained for 30 s was performed in 50 sedated ventilated patients within the first 24 h of meeting ARDS criteria. Invasive arterial pressures, heart rate, and SpO2 were measured at 10-s intervals during the RM. The volume increase during the RM was measured by integration of the flow required to maintain the pressure at 40 cmH2O, which provides an estimation of the volume recruited during the RM. Raw data were corrected for gas consumption and fitted with an exponential curve in order to determine an individual time constant for the volume increase.

Results

The average volume increase and time constant were 210 ± 198 mL and 2.3 ± 1.3 s, respectively. Heart rate, diastolic arterial pressure, and SpO2 did not change during or after the RM. Systolic and mean arterial pressures were maintained at 10 s, decreased significantly at 20 and 30 s during the RM, and recovered to the pre-RM value 30 s after the end of the RM (ANOVA, p < 0.01).

Conclusions

In early-onset ARDS patients, most of the recruitment occurs during the first 10 s of a sustained inflation RM. However, hemodynamic impairment is significant after the tenth second of RM.
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Metadata
Title
Optimal duration of a sustained inflation recruitment maneuver in ARDS patients
Authors
Jean-Michel Arnal
Jérémie Paquet
Marc Wysocki
Didier Demory
Stéphane Donati
Isabelle Granier
Gaëlle Corno
Jacques Durand-Gasselin
Publication date
01-10-2011
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 10/2011
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-011-2323-0

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