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Published in: Intensive Care Medicine 6/2010

01-06-2010 | Correspondence

Reply to Oltean and Olausson

Authors: Ke Xuan Liu, Yun Sheng Li, Wen Qi Huang, Shu Qin Chen, Zhong Xin Wang, Jia Xin Liu

Published in: Intensive Care Medicine | Issue 6/2010

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Excerpt

Dear Sir: We thank Dr. Oltean and Olausson for their interest regarding our work [1]. We agree with Dr. Oltean and Olausson that the scoring system for intestinal ischemia–reperfusion initially proposed by Chiu [2] and later completed by Park et al. [3] is reliable and reproducible. However, in our opinion, the modified Chiu’s score is also a good method by which to grade intestinal ischemia–reperfusion injury for the following reasons. In the studies performed by Hei et al. [4], Cao et al. [5] and Zhang et al. [6], the modified Chiu’s score was used to grade intestinal ischemia–reperfusion injury. Their results showed that the modified Chiu’s score could also clearly distinguish the extent of intestinal injury. That means that this scoring system has been accepted by other researchers. Secondly, we had consulted two senior pathologists before choosing scoring systems for our experiments, and both of them thought that the modified Chiu’s score was the same as Chiu’s score in nature, but modified Chiu’s score provided more detail in grading the extent of intestinal injury. Moreover, we used Chiu’s score to evaluate intestinal injury at the same time and got the same results as we did with the modified Chiu’s score in terms of the relative severity of injury among groups. Taken together, modified Chiu’s score is as effective as Chiu’s score for grading intestinal ischemia–reperfusion injury. Finally, in order to further confirm the existence of intestinal injury, we also employed two additional variables, intestinal lactic acid level and wet-to-dry weight ratio, and the results were in line with findings obtained with the modified Chiu’s score. …
Literature
1.
go back to reference Liu KX, Li YS, Huang WQ, Chen SQ, Wang ZX, Liu JX, Xia Z (2009) Immediate postconditioning during reperfusion attenuates intestinal injury. Intensive Care Med 35:933–942CrossRefPubMed Liu KX, Li YS, Huang WQ, Chen SQ, Wang ZX, Liu JX, Xia Z (2009) Immediate postconditioning during reperfusion attenuates intestinal injury. Intensive Care Med 35:933–942CrossRefPubMed
2.
go back to reference Chiu CJ, McArdle AH, Brown R, Scott HJ, Gurd FN (1970) Intestinal mucosal lesion in low-flow states. I. A morphological, hemodynamic, and metabolic reappraisal. Arch Surg 101:478–483PubMed Chiu CJ, McArdle AH, Brown R, Scott HJ, Gurd FN (1970) Intestinal mucosal lesion in low-flow states. I. A morphological, hemodynamic, and metabolic reappraisal. Arch Surg 101:478–483PubMed
3.
go back to reference Park PO, Haglund U, Bulkley GB, Fält K (1990) The sequence of development of intestinal tissue injury after strangulation ischemia and reperfusion. Surgery 107:574–580PubMed Park PO, Haglund U, Bulkley GB, Fält K (1990) The sequence of development of intestinal tissue injury after strangulation ischemia and reperfusion. Surgery 107:574–580PubMed
4.
go back to reference Hei ZQ, Huang HQ, Zhang JJ, Chen BX, Li XY (2005) Protective effect of Astragalus membranaceus on intestinal mucosa reperfusion injury after hemorrhagic shock in rats. World J Gastroenterol 11:4986–4991PubMed Hei ZQ, Huang HQ, Zhang JJ, Chen BX, Li XY (2005) Protective effect of Astragalus membranaceus on intestinal mucosa reperfusion injury after hemorrhagic shock in rats. World J Gastroenterol 11:4986–4991PubMed
5.
go back to reference Bin Cao, Ning Li, Yong Wang, Li JS (2005) Protective effect of l-arginine preconditioning on ischemia and reperfusion injury associated with rat small bowel transplantation. World J Gastroenterol 1:2994–2997 Bin Cao, Ning Li, Yong Wang, Li JS (2005) Protective effect of l-arginine preconditioning on ischemia and reperfusion injury associated with rat small bowel transplantation. World J Gastroenterol 1:2994–2997
6.
go back to reference Zhang W, Zhu WM, Zhang J, Li JS (2008) Protective effects of glucagon-like peptide 2 on intestinal ischemia–reperfusion rats. Microsurgery 28:285–290CrossRefPubMed Zhang W, Zhu WM, Zhang J, Li JS (2008) Protective effects of glucagon-like peptide 2 on intestinal ischemia–reperfusion rats. Microsurgery 28:285–290CrossRefPubMed
7.
go back to reference Lindestrom LM, Ekblad E (2004) Structural and neuronal changes in rat ileum after ischemia with reperfusion. Dig Dis Sci 49:1212–1222CrossRefPubMed Lindestrom LM, Ekblad E (2004) Structural and neuronal changes in rat ileum after ischemia with reperfusion. Dig Dis Sci 49:1212–1222CrossRefPubMed
8.
go back to reference Wu B, Ootani A, Iwakiri R, Fujise T, Tsunada S, Toda S, Fujimoto K (2004) Ischemic preconditioning attenuates ischemia–reperfusion-induced mucosal apoptosis by inhibiting the mitochondria-dependent pathway in rat small intestine. Gastrointest Liver Physiol 286:580–587CrossRef Wu B, Ootani A, Iwakiri R, Fujise T, Tsunada S, Toda S, Fujimoto K (2004) Ischemic preconditioning attenuates ischemia–reperfusion-induced mucosal apoptosis by inhibiting the mitochondria-dependent pathway in rat small intestine. Gastrointest Liver Physiol 286:580–587CrossRef
9.
go back to reference Sileri P, Sica G, Gentileschi P, Venza M, Manzelli A, Palmieri G, Spagnoli LG, Testa G, Benedetti E, Gaspari AL (2004) Ischemic preconditioning protects intestine from prolonged ischemia. Transpl Proc 36:283–285CrossRef Sileri P, Sica G, Gentileschi P, Venza M, Manzelli A, Palmieri G, Spagnoli LG, Testa G, Benedetti E, Gaspari AL (2004) Ischemic preconditioning protects intestine from prolonged ischemia. Transpl Proc 36:283–285CrossRef
10.
go back to reference Aksöyek S, Cinel I, Avlan D, Cinel L, Oztürk C, Gürbüz P, Nayci A, Oral U (2002) Intestinal ischemic preconditioning protects the intestine and reduces bacterial translocation. Shock 18:476–480CrossRefPubMed Aksöyek S, Cinel I, Avlan D, Cinel L, Oztürk C, Gürbüz P, Nayci A, Oral U (2002) Intestinal ischemic preconditioning protects the intestine and reduces bacterial translocation. Shock 18:476–480CrossRefPubMed
Metadata
Title
Reply to Oltean and Olausson
Authors
Ke Xuan Liu
Yun Sheng Li
Wen Qi Huang
Shu Qin Chen
Zhong Xin Wang
Jia Xin Liu
Publication date
01-06-2010
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 6/2010
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-010-1813-9

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