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Intensive Care Medicine

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01-04-2010 | Pediatric Brief Report

Chest compressions versus ventilation plus chest compressions in a pediatric asphyxial cardiac arrest animal model

Authors: Jose María Iglesias, Jesús López-Herce, Javier Urbano, Maria José Solana, Santiago Mencía, Jimena del Castillo

Published in: Intensive Care Medicine | Issue 4/2010

Abstract

Objective

To compare the ventilation achieved with chest compressions (CC) or ventilation plus compressions (VC) in a pediatric animal model of cardiac arrest.

Design

Randomized experimental study.

Setting

Experimental department of a University Hospital.

Methods

Twelve infant pigs with asphyxial cardiac arrest. Sequential 3-min periods of VC and CC were performed for a total duration of 9 min. Tidal volume (TV), end-tidal CO₂ (EtCO₂), mean arterial pressure (MAP), central venous pressure (CVP), mean pulmonary arterial pressure (mPAP), and peripheral, cerebral, and renal saturations were recorded and arterial and venous blood gases were analyzed.

Results

VC achieved a TV similar to the preset parameters on the ventilator, whilst the TV in CC was very low (P < 0.001). EtCO₂ with VC was significantly higher than with CC (14.0 vs. 3.9 mmHg, P < 0.05). Arterial pH was higher with VC than with CC (6.99 vs. 6.90 mmHg, P < 0.05). Arterial PCO₂ was lower with VC than with CC (62.1 vs. 97.0 mmHg, P < 0.05). There were no significant differences in the MAP; CVP; mPAP; peripheral, renal, and cerebral saturations; or lactate concentrations between the two techniques.

Conclusions

VC achieves better ventilation than CC during cardiopulmonary resuscitation and has no negative effect on the hemodynamic situation.

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Title: Chest compressions versus ventilation plus chest compressions in a pediatric asphyxial cardiac arrest animal model
Authors: Jose María Iglesias
Jesús López-Herce
Javier Urbano
Maria José Solana
Santiago Mencía
Jimena del Castillo
Publication date: 01-04-2010
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 4/2010
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-010-1777-9

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Chest compressions versus ventilation plus chest compressions in a pediatric asphyxial cardiac arrest animal model

Abstract

Objective

Design

Setting

Methods

Results

Conclusions

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