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Intensive Care Medicine

Published in:

01-04-2010 | Original

Estimation of inspiratory muscle pressure in critically ill patients

Authors: Eumorfia Kondili, Christina Alexopoulou, Nectaria Xirouchaki, Katerina Vaporidi, Dimitris Georgopoulos

Published in: Intensive Care Medicine | Issue 4/2010

Abstract

Background

Recently, a new technology has been introduced aiming to monitor and improve patient ventilator interaction (PVI monitor). With the PVI monitor, a signal representing an estimation of the patient’s total inspiratory muscle pressure (Pmus_PVI) is calculated from the equation of motion, utilizing estimated values of resistance and elastance of the respiratory system.

Objective

The aim of the study was to prospectively examine the accuracy of Pmus_PVI to quantify inspiratory muscle pressure.

Methods and interventions

Eleven critically ill patients mechanically ventilated on proportional assist ventilation with load-adjustable gain factors were studied at three levels of assist (30, 50 and 70%). Airway, esophageal, gastric and transdiaphragmatic (Pdi) pressures, volume and flow were measured breath by breath, whereas the total inspiratory muscle pressure (Pmus) was calculated using the Campbell diagram.

Results

For a given assist, Pmus_PVI throughout inspiration did not differ from the corresponding values calculated using the Pdi and Pmus signals. Inspiratory and expiratory time did not differ among the various methods of calculation. Inspiratory muscle pressure decreased with increasing assist, and the magnitude of this decrease did not differ among the various methods of pressure calculation.

Conclusions

A signal generated from flow, volume and airway pressure may be used to provide breath-by-breath quantitative information of inspiratory muscle pressure.

Available only for authorised users

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Title: Estimation of inspiratory muscle pressure in critically ill patients
Authors: Eumorfia Kondili
Christina Alexopoulou
Nectaria Xirouchaki
Katerina Vaporidi
Dimitris Georgopoulos
Publication date: 01-04-2010
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 4/2010
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-010-1753-4

At a glance: The STEP trials

Springer Medicine

Estimation of inspiratory muscle pressure in critically ill patients

Abstract

Background

Objective

Methods and interventions

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Objective

Methods and interventions

Results

Conclusions

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