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Open Access 01-01-2010 | Correspondence

Glucontrol, no control, or out of control?

Authors: Marcus J. Schultz, Peter E. Spronk, Floris van Braam Houckgeest

Published in: Intensive Care Medicine | Issue 1/2010

Excerpt

Sir: Preiser et al. [1] are to be congratulated on their randomized controlled multi-center trial on tight glycemic control (TGC) in critically ill patients. This trial adds to our knowledge of glucose control in intensive care units, but also poses a fascinating dilemma. While we need confirmation of the effects of TGC observed in Leuven, we notice at the same time that the Leuven trials have already changed the standard of care against which we compare TGC. …

Preiser JC, Devos P, Ruiz-Santana S, Melot C, Annane D, Groeneveld J, Iapichino G, Leverve X, Nitenberg G, Singer P, Wernerman J, Joannidis M, Stecher A, Chiolero R (2009) A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study. Intensive Care Med 35:1738–1748

Van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouillon R (2001) Intensive insulin therapy in the critically ill patients. N Engl J Med 345:1359–1367CrossRefPubMed

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Van den Berghe G, Wilmer A, Milants I, Wouters PJ, Bouckaert B, Bruyninckx F, Bouillon R, Schetz M (2006) Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harm. Diabetes 55:3151–3159CrossRefPubMed

Title: Glucontrol, no control, or out of control?
Authors: Marcus J. Schultz
Peter E. Spronk
Floris van Braam Houckgeest
Publication date: 01-01-2010
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 1/2010
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-009-1666-2

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Glucontrol, no control, or out of control?

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Keynote webinar | Spotlight on medication adherence

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