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Published in: Intensive Care Medicine 9/2005

01-09-2005 | Original

Lung recruitment maneuver depresses central hemodynamics in patients following cardiac surgery

Authors: Jonas Nielsen, Morten Østergaard, Jesper Kjaergaard, Jens Tingleff, Preben G. Berthelsen, Eigil Nygård, Anders Larsson

Published in: Intensive Care Medicine | Issue 9/2005

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Abstract

Objective

To assess the impact of the lung recruitment maneuver on circulation following cardiac surgery.

Design and setting

Prospective randomized cross-over study at the Departments of Anesthesia and Thoracic Surgery, Copenhagen University Hospital.

Patients

Ten adult undergoing coronary artery bypass surgery.

Interventions

Patients were randomized to two durations of lung recruitment maneuvers (40 cmH2O airway pressure for 10 s and 20 s or vice versa after 5 min) administered immediately after surgery.

Measurements and results

Transesophageal echocardiography (left ventricular short axis view), pulse contour cardiac output, and arterial blood pressure were monitored continuously. Systemic and pulmonary arterial blood gases were sampled before and after each lung recruitment maneuver to calculate the intrapulmonary shunt. Left ventricular end-diastolic areas decreased significantly during both the 10-s and the 20-s lung recruitment maneuvers. Cardiac output was 5.6±0.8 l/min at baseline, decreasing by 3.0±1.1 l/min and 3.6±1.2 l/min during lung recruitment maneuvers of 10 and 20 s, respectively. Shunt decreased from 20±5% to 15±6% after the first lung recruitment maneuver and from 15±6% to 12±5% after the second.

Conclusions

Lung recruitment maneuvers markedly reduced cardiac output and left ventricular end-diastolic areas in hemodynamically stable patients following cardiac surgery.
Literature
1.
go back to reference Gale GD, Teasdale SJ, Sanders DE, Bradwell PJ, Russell A, Solaric B, York JE (1979) Pulmonary atelectasis and other respiratory complications after cardiopulmonary bypass and investigation of aetiological factors. Can Anaesth Soc J 26:15–21PubMed Gale GD, Teasdale SJ, Sanders DE, Bradwell PJ, Russell A, Solaric B, York JE (1979) Pulmonary atelectasis and other respiratory complications after cardiopulmonary bypass and investigation of aetiological factors. Can Anaesth Soc J 26:15–21PubMed
2.
go back to reference Magnusson L, Zemgulis V, Wicky S, Tyden H, Thelin S, Hedenstierna G (1997) Atelectasis is a major cause of hypoxemia and shunt after cardiopulmonary bypass: an experimental study. Anesthesiology 87:1153–1163CrossRefPubMed Magnusson L, Zemgulis V, Wicky S, Tyden H, Thelin S, Hedenstierna G (1997) Atelectasis is a major cause of hypoxemia and shunt after cardiopulmonary bypass: an experimental study. Anesthesiology 87:1153–1163CrossRefPubMed
3.
go back to reference Hachenberg T, Tenling A, Nystrom SO, Tyden H, Hedenstierna G (1994) Ventilation-perfusion inequality in patients undergoing cardiac surgery. Anesthesiology 80:509–519PubMed Hachenberg T, Tenling A, Nystrom SO, Tyden H, Hedenstierna G (1994) Ventilation-perfusion inequality in patients undergoing cardiac surgery. Anesthesiology 80:509–519PubMed
4.
go back to reference Dyhr T, Laursen N, Larsson A (2002) Effects of lung recruitment maneuver and positive end-expiratory pressure on lung volume, respiratory mechanics and alveolar gas mixing in patients ventilated after cardiac surgery. Acta Anaesthesiol Scand 46:717–725CrossRefPubMed Dyhr T, Laursen N, Larsson A (2002) Effects of lung recruitment maneuver and positive end-expiratory pressure on lung volume, respiratory mechanics and alveolar gas mixing in patients ventilated after cardiac surgery. Acta Anaesthesiol Scand 46:717–725CrossRefPubMed
5.
go back to reference Dyhr T, Nygard E, Laursen N, Larsson A (2004) Both lung recruitment maneuver and PEEP are needed to increase oxygenation and lung volume after cardiac surgery. Acta Anaesthesiol Scand 48:187–197CrossRefPubMed Dyhr T, Nygard E, Laursen N, Larsson A (2004) Both lung recruitment maneuver and PEEP are needed to increase oxygenation and lung volume after cardiac surgery. Acta Anaesthesiol Scand 48:187–197CrossRefPubMed
6.
go back to reference Nunes S, Rothen HU, Brander L, Takala J, Jakob SM (2004) Changes in splanchnic circulation during an alveolar recruitment maneuver in healthy porcine lungs. Anesth Analg 98:1432–1438PubMed Nunes S, Rothen HU, Brander L, Takala J, Jakob SM (2004) Changes in splanchnic circulation during an alveolar recruitment maneuver in healthy porcine lungs. Anesth Analg 98:1432–1438PubMed
7.
go back to reference Lim SC, Adams AB, Simonson DA, Dries DJ, Broccard AF, Hotchkiss JR, Marini JJ (2004) Transient hemodynamic effects of recruitment maneuvers in three experimental models of acute lung injury. Crit Care Med 32:2378–2384CrossRefPubMed Lim SC, Adams AB, Simonson DA, Dries DJ, Broccard AF, Hotchkiss JR, Marini JJ (2004) Transient hemodynamic effects of recruitment maneuvers in three experimental models of acute lung injury. Crit Care Med 32:2378–2384CrossRefPubMed
8.
go back to reference Odenstedt H, Aneman A, Karason S, Stenqvist O, Lundin S (2005) Acute hemodynamic changes during lung recruitment in lavage and endotoxin-induced ALI. Intensive Care Med 31:112–120CrossRefPubMed Odenstedt H, Aneman A, Karason S, Stenqvist O, Lundin S (2005) Acute hemodynamic changes during lung recruitment in lavage and endotoxin-induced ALI. Intensive Care Med 31:112–120CrossRefPubMed
9.
go back to reference Rothen HU, Neumann P, Berglund JE, Valtysson J, Magnusson A, Hedenstierna G (1999) Dynamics of re-expansion of atelectasis during general anaesthesia. Br J Anaesth 82:551–556PubMed Rothen HU, Neumann P, Berglund JE, Valtysson J, Magnusson A, Hedenstierna G (1999) Dynamics of re-expansion of atelectasis during general anaesthesia. Br J Anaesth 82:551–556PubMed
10.
go back to reference Fujino Y, Goddon S, Dolhnikoff M, Hess D, Amato MB, Kacmarek RM (2001) Repetitive high-pressure recruitment maneuvers required to maximally recruit lung in a sheep model of acute respiratory distress syndrome. Crit Care Med 29:1579–1586CrossRefPubMed Fujino Y, Goddon S, Dolhnikoff M, Hess D, Amato MB, Kacmarek RM (2001) Repetitive high-pressure recruitment maneuvers required to maximally recruit lung in a sheep model of acute respiratory distress syndrome. Crit Care Med 29:1579–1586CrossRefPubMed
11.
go back to reference Ryan T, Petrovic O, Dillon JC, Feigenbaum H, Conley MJ, Armstrong WF (1985) An echocardiographic index for separation of right ventricular volume and pressure overload. J Am Coll Cardiol 5:918–927PubMed Ryan T, Petrovic O, Dillon JC, Feigenbaum H, Conley MJ, Armstrong WF (1985) An echocardiographic index for separation of right ventricular volume and pressure overload. J Am Coll Cardiol 5:918–927PubMed
12.
13.
go back to reference Rothen HU, Sporre B, Engberg G, Wegenius G, Hedenstierna G (1993) Re-expansion of atelectasis during general anaesthesia: a computed tomography study. Br J Anaesth 71:788–795PubMed Rothen HU, Sporre B, Engberg G, Wegenius G, Hedenstierna G (1993) Re-expansion of atelectasis during general anaesthesia: a computed tomography study. Br J Anaesth 71:788–795PubMed
14.
go back to reference Pinsky MR (1997) The hemodynamic consequences of mechanical ventilation: an evolving story. Intensive Care Med 23:493–503CrossRefPubMed Pinsky MR (1997) The hemodynamic consequences of mechanical ventilation: an evolving story. Intensive Care Med 23:493–503CrossRefPubMed
15.
go back to reference Berg PC van den, Grimbergen CA, Spaan JA, Pinsky MR (1997) Positive pressure inspiration differentially affects right and left ventricular outputs in postoperative cardiac surgery patients. J Crit Care 12:56–65CrossRefPubMed Berg PC van den, Grimbergen CA, Spaan JA, Pinsky MR (1997) Positive pressure inspiration differentially affects right and left ventricular outputs in postoperative cardiac surgery patients. J Crit Care 12:56–65CrossRefPubMed
16.
go back to reference Qvist J, Pontoppidan H, Wilson RS, Lowenstein E, Laver MB (1975) Hemodynamic responses to mechanical ventilation with PEEP: the effect of hypervolemia. Anesthesiology 42:45–55PubMed Qvist J, Pontoppidan H, Wilson RS, Lowenstein E, Laver MB (1975) Hemodynamic responses to mechanical ventilation with PEEP: the effect of hypervolemia. Anesthesiology 42:45–55PubMed
17.
go back to reference Dhainaut JF, Devaux JY, Monsallier JF, Brunet F, Villemant D, Huyghebaert MF (1986) Mechanisms of decreased left ventricular preload during continuous positive pressure ventilation in ARDS. Chest 90:74–80PubMed Dhainaut JF, Devaux JY, Monsallier JF, Brunet F, Villemant D, Huyghebaert MF (1986) Mechanisms of decreased left ventricular preload during continuous positive pressure ventilation in ARDS. Chest 90:74–80PubMed
18.
go back to reference Grasso S, Mascia L, Del Turco M, Malacarne P, Giunta F, Brochard L, Slutsky AS, Ranieri VM (2002) Effects of recruiting maneuvers in patients with acute respiratory distress syndrome ventilated with protective ventilatory strategy. Anesthesiology 96:795–802CrossRefPubMed Grasso S, Mascia L, Del Turco M, Malacarne P, Giunta F, Brochard L, Slutsky AS, Ranieri VM (2002) Effects of recruiting maneuvers in patients with acute respiratory distress syndrome ventilated with protective ventilatory strategy. Anesthesiology 96:795–802CrossRefPubMed
19.
go back to reference Lapinsky SE, Aubin M, Mehta S, Boiteau P, Slutsky AS (1999) Safety and efficacy of a sustained inflation for alveolar recruitment in adults with respiratory failure. Intensive Care Med 25:1297–1301PubMed Lapinsky SE, Aubin M, Mehta S, Boiteau P, Slutsky AS (1999) Safety and efficacy of a sustained inflation for alveolar recruitment in adults with respiratory failure. Intensive Care Med 25:1297–1301PubMed
20.
go back to reference Godje O, Hoke K, Goetz AE, Felbinger TW, Reuter DA, Reichart B, Friedl R, Hannekum A, Pfeiffer UJ (2002 Reliability of a new algorithm for continuous cardiac output determination by pulse-contour analysis during hemodynamic instability. Crit Care Med 30:52–58CrossRefPubMed Godje O, Hoke K, Goetz AE, Felbinger TW, Reuter DA, Reichart B, Friedl R, Hannekum A, Pfeiffer UJ (2002 Reliability of a new algorithm for continuous cardiac output determination by pulse-contour analysis during hemodynamic instability. Crit Care Med 30:52–58CrossRefPubMed
21.
go back to reference Pinsky MR (2003) Probing the limits of arterial pulse contour analysis to predict preload responsiveness. Anesth Analg 96:1245–1247CrossRefPubMed Pinsky MR (2003) Probing the limits of arterial pulse contour analysis to predict preload responsiveness. Anesth Analg 96:1245–1247CrossRefPubMed
22.
go back to reference Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet I:307–310 Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet I:307–310
23.
go back to reference Teichholz LE, Kreulen T, Herman MV, Gorlin R (1976) Problems in echocardiographic volume determinations: echocardiographic-angiographic correlations in the presence of absence of asynergy. Am J Cardiol 37:7–11CrossRefPubMed Teichholz LE, Kreulen T, Herman MV, Gorlin R (1976) Problems in echocardiographic volume determinations: echocardiographic-angiographic correlations in the presence of absence of asynergy. Am J Cardiol 37:7–11CrossRefPubMed
24.
go back to reference Whittenberger JL, McGregor M, Berglund E, Borst HG (1960) Influence of state of inflation of the lung on pulmonary vascular resistance. J Appl Physiol 15:878–882PubMed Whittenberger JL, McGregor M, Berglund E, Borst HG (1960) Influence of state of inflation of the lung on pulmonary vascular resistance. J Appl Physiol 15:878–882PubMed
25.
go back to reference Brinker JA, Weiss JL, Lappe DL, Rabson JL, Summer WR, Permutt S, Weisfeldt ML (1980) Leftward septal displacement during right ventricular loading in man. Circulation 61:626–633PubMed Brinker JA, Weiss JL, Lappe DL, Rabson JL, Summer WR, Permutt S, Weisfeldt ML (1980) Leftward septal displacement during right ventricular loading in man. Circulation 61:626–633PubMed
26.
go back to reference Jardin F, Farcot JC, Boisante L, Curien N, Margairaz A, Bourdarias JP (1981) Influence of positive end-expiratory pressure on left ventricular performance. N Engl J Med 304:387–392PubMed Jardin F, Farcot JC, Boisante L, Curien N, Margairaz A, Bourdarias JP (1981) Influence of positive end-expiratory pressure on left ventricular performance. N Engl J Med 304:387–392PubMed
27.
go back to reference Jardin F, Delorme G, Hardy A, Auvert B, Beauchet A, Bourdarias JP (1990) Reevaluation of hemodynamic consequences of positive pressure ventilation: emphasis on cyclic right ventricular afterloading by mechanical lung inflation. Anesthesiology 72:966–970PubMed Jardin F, Delorme G, Hardy A, Auvert B, Beauchet A, Bourdarias JP (1990) Reevaluation of hemodynamic consequences of positive pressure ventilation: emphasis on cyclic right ventricular afterloading by mechanical lung inflation. Anesthesiology 72:966–970PubMed
28.
go back to reference Vieillard-Baron A, Loubieres Y, Schmitt JM, Page B, Dubourg O, Jardin F (1999) Cyclic changes in right ventricular output impedance during mechanical ventilation. J Appl Physiol 87:1644–1650PubMed Vieillard-Baron A, Loubieres Y, Schmitt JM, Page B, Dubourg O, Jardin F (1999) Cyclic changes in right ventricular output impedance during mechanical ventilation. J Appl Physiol 87:1644–1650PubMed
29.
go back to reference Versprille A, Jansen JR (1985) Mean systemic filling pressure as a characteristic pressure for venous return. Pflugers Arch 405:226–233CrossRefPubMed Versprille A, Jansen JR (1985) Mean systemic filling pressure as a characteristic pressure for venous return. Pflugers Arch 405:226–233CrossRefPubMed
30.
go back to reference Vieillard-Baron A, Jardin F (2003) Why protect the right ventricle in patients with acute respiratory distress syndrome? Curr Opin Crit Care 9:15–21CrossRefPubMed Vieillard-Baron A, Jardin F (2003) Why protect the right ventricle in patients with acute respiratory distress syndrome? Curr Opin Crit Care 9:15–21CrossRefPubMed
31.
go back to reference Buda AJ, Pinsky MR, Ingels NB Jr, Daughters GT, Stinson EB, Alderman EL (1979) Effect of intrathoracic pressure on left ventricular performance. N Engl J Med 301:453–459PubMed Buda AJ, Pinsky MR, Ingels NB Jr, Daughters GT, Stinson EB, Alderman EL (1979) Effect of intrathoracic pressure on left ventricular performance. N Engl J Med 301:453–459PubMed
32.
go back to reference Campagna JA, Carter C (2003) Clinical relevance of the Bezold-Jarisch reflex. Anesthesiology 98:1250–1260PubMed Campagna JA, Carter C (2003) Clinical relevance of the Bezold-Jarisch reflex. Anesthesiology 98:1250–1260PubMed
Metadata
Title
Lung recruitment maneuver depresses central hemodynamics in patients following cardiac surgery
Authors
Jonas Nielsen
Morten Østergaard
Jesper Kjaergaard
Jens Tingleff
Preben G. Berthelsen
Eigil Nygård
Anders Larsson
Publication date
01-09-2005
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 9/2005
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-005-2732-z

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