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Intensive Care Medicine
Published in: Intensive Care Medicine 12/2005

01-12-2005 | Editorial

Weaning failure from cardiovascular origin

Authors: Christian Richard, Jean Louis Teboul

Published in: Intensive Care Medicine | Issue 12/2005

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Excerpt

The goal in weaning from mechanical ventilation (MV) is to induce spontaneous breathing (SB) and ultimately extubation. Weaning fails in about 25% of patients meeting weaning criteria and is particularly frequent in patients with chronic obstructive pulmonary disease (COPD) and/or left heart disease [1]. Weaning failure prolongs the duration of MV and increases morbidity and mortality in these critically ill patients [2]. Thus early identification and treatment of the causes of weaning failure is of paramount importance to improve outcome in difficult-to-wean patients. …
Literature
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Brochard L, Rauss A, Benito S, Conti G, Mancebo J, Rekik N, Gasparetto A, Lemaire F (1994) Comparison of three methods of gradual withdrawal from ventilatory support during weaning from mechanical ventilation. Am J Respir Crit Care Med 150:896–903PubMed
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Ely EW, Baker AM, Dunagan DP, Burke HL, Smith AC, Kelly PT, Johnson MM, Browder RW, Bowton DL, Haponik EF (1996) Effect on the duration of mechanical ventilation of identifying patients capable of breathing spontaneously. N Engl J Med 335:1864–1869CrossRefPubMed
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Pinsky MR (2000) Breathing as exercise: the cardiovascular response to weaning from mechanical ventilation. Intensive Care Med 26:1164–1166CrossRefPubMed
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Lamia B, Monnet X, Teboul JL (2005) Weaning-induced cardiac dysfunction. In Vincent JL (ed) Yearbook of intensive care and emergency medicine. Springer, Berlin Heidelberg New York, pp 239–245
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Lemaire F, Teboul JL, Cinotti L, Giotto G, Abrouk F, Steg G, Macquin-Mavier I, Zapol W (1988) Acute left ventricular dysfunction during unsuccessful weaning from mechanical ventilation. Anesthesiology 69:171–179PubMed
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Mekontso-Dessap A, De Prost N, Braconnier F, Lemaire F, Brun-Buisson C, Brochard L (2004) B type natriuretic peptide and weaning from mechanical ventilation. Intensive Care Med 30: S182
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Cabello B, Mancebo J (2003) Withdrawal from mechanical ventilation in patients with COPD: the issue of congestive heart failure. In: Vincent JL (ed) Yearbook of intensive care and emergency medicine. Springer, Berlin Heidelberg New York, pp 295–301
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Jubran A, Mathru M, Dries D, Tobin M (1998) Continuous recordings of mixed venous oxygen saturation during weaning from mechanical ventilation and the ramifications thereof. Am J Respir Crit Care Med 158:1763–1769PubMed
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Zakynthinos S, Routsi C, Vassilakopoulos T, Kaltsas P, Zakynthinos E, Kazi D, Roussos C (2005) Differential cardio-vascular responses during weaning failure: effects on tissue oxygenation and lactate. Intensive Care Med (DOI: 10.​1007/​s00134-005-2699-9)
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De Backer D, El Haddad P, Preiser JC, Vincent JL (2000) Hemodynamic responses to successful weaning from mechanical ventilation after cardiovascular surgery. Intensive Care Med 26:1201–1206CrossRefPubMed
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Metadata
Title
Weaning failure from cardiovascular origin
Authors
Christian Richard
Jean Louis Teboul
Publication date
01-12-2005
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 12/2005
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-005-2698-x

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