Skip to main content
Top
Published in: Intensive Care Medicine 3/2003

01-03-2003 | Expert Panel

Surviving Intensive Care: a report from the 2002 Brussels Roundtable

Authors: Derek C. Angus, Jean Carlet, on behalf of the 2002 Brussels Roundtable Participants

Published in: Intensive Care Medicine | Issue 3/2003

Login to get access

Abstract

The traditional goal of intensive care has been to decrease short-term mortality. While worthy, this goal fails to address the issue of what it means to survive intensive care. Key questions include whether intensive care survivors have optimal long-term outcomes and whether ICU care decisions would change if we knew more about these outcomes. The 2002 Brussels Roundtable, "Surviving Intensive care", highlighted these issues, summarizing the available evidence on natural history and risk factors for critical illness and outlining future directions for care and research. Critical illness is associated with a wide array of serious and concerning long-term sequelae that interfere with optimal patient-centered outcomes. Although traditional short-term outcomes, such as hospital mortality, remain extremely important, they are not likely to be adequate surrogates for subsequent patient-centered outcomes. As such, it is important to focus specifically on how critical illness and intensive care affects a patient's and relatives' long-term health and well-being. There are a large number of potential pre-, intra-, and post-ICU factors that may improve or worsen these outcomes, and these factors are subjects for future research. In addition, future clinical trials of ICU therapies should include long-term follow-up of survival, quality of life, morbidity, functional status, and costs of care. Follow-up ought to be for at least six months. The SF-36 and EuroQOL EQ-5D are the best-suited instruments for measuring quality of life in multicenter critical care trials though further methodologic research and instrument design is encouraged. There are also opportunities today to improve care. Key to taking advantage of such opportunities is the need for a global awareness of critical illness as an entity that begins and ends outside the ICU 'box'. Specific interventions that show promise for improving care include ICU discharge screening tools and ICU follow-up clinics.
Appendix
Available only for authorised users
Literature
1.
go back to reference Angus DC, Carlet J (eds) (2002) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York Angus DC, Carlet J (eds) (2002) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
2.
go back to reference Keenan SP, Dodek P (2002) Survival as an outcome for ICU patients. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York Keenan SP, Dodek P (2002) Survival as an outcome for ICU patients. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
3.
go back to reference Ely EW (2002) Understanding outcomes of critically ill older patients. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York Ely EW (2002) Understanding outcomes of critically ill older patients. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
4.
go back to reference Herridge MS (2002) Morbidity and functional limitations in survivors of ARDS. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York Herridge MS (2002) Morbidity and functional limitations in survivors of ARDS. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
5.
go back to reference Randolph AG, Graham R (2002) Measuring the health status of pediatric ICU survivors. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York Randolph AG, Graham R (2002) Measuring the health status of pediatric ICU survivors. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
6.
go back to reference Sukantarat KT, Brett S (2002) The neuropsychological consequences of intensive care. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York Sukantarat KT, Brett S (2002) The neuropsychological consequences of intensive care. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
7.
go back to reference Rowan K, Jenkinson C, Black N (2002) Health-related quality of life. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York Rowan K, Jenkinson C, Black N (2002) Health-related quality of life. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
8.
go back to reference Levy MM (2002) The burden of caregiving on families of ICU survivors. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York Levy MM (2002) The burden of caregiving on families of ICU survivors. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
9.
go back to reference Kalassian KG, Angus DC (2002) Long-term economic consequences of surviving intensive care. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York Kalassian KG, Angus DC (2002) Long-term economic consequences of surviving intensive care. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
10.
go back to reference Quartin AA, Schein RM, Kett DH, Peduzzi PN, for the Department of Veterans Affairs Systemic Sepsis Cooperative Studies Group (1997) Magnitude and duration of the effect of sepsis on survival. JAMA 277:1058–1063PubMed Quartin AA, Schein RM, Kett DH, Peduzzi PN, for the Department of Veterans Affairs Systemic Sepsis Cooperative Studies Group (1997) Magnitude and duration of the effect of sepsis on survival. JAMA 277:1058–1063PubMed
11.
go back to reference Keenan SP, Dodek P, Chan K, Hogg RS, Craib KJP, Anis AH, Spinelli JJ (2002) Intensive care unit admission has minimal impact on long-term mortality. Crit Care Med 30:501–507PubMed Keenan SP, Dodek P, Chan K, Hogg RS, Craib KJP, Anis AH, Spinelli JJ (2002) Intensive care unit admission has minimal impact on long-term mortality. Crit Care Med 30:501–507PubMed
12.
go back to reference Kaplan V, Clermont G, Griffin MF, Kasal J, Watson RS, Linde-Zwirble WT, Angus DC (2002) Pneumonia-still the old man's friend? Arch Intern Med (in press) Kaplan V, Clermont G, Griffin MF, Kasal J, Watson RS, Linde-Zwirble WT, Angus DC (2002) Pneumonia-still the old man's friend? Arch Intern Med (in press)
13.
go back to reference Angus DC, Musthafa AA, Clermont G, Griffin MF, Linde-Zwirble WT, Dremsizov TT, Pinsky MR (2001) Quality-adjusted survival in the first year after the acute respiratory distress syndrome. Am J Respir Crit Care Med 163:1389–1394PubMed Angus DC, Musthafa AA, Clermont G, Griffin MF, Linde-Zwirble WT, Dremsizov TT, Pinsky MR (2001) Quality-adjusted survival in the first year after the acute respiratory distress syndrome. Am J Respir Crit Care Med 163:1389–1394PubMed
14.
go back to reference Davidson TA, Rubenfeld GD, Caldwell ES, Hudson LD, Steinberg KP (1999) The effect of acute respiratory distress syndrome on long-term survival. Am J Respir Crit Care Med 160:1838–1842PubMed Davidson TA, Rubenfeld GD, Caldwell ES, Hudson LD, Steinberg KP (1999) The effect of acute respiratory distress syndrome on long-term survival. Am J Respir Crit Care Med 160:1838–1842PubMed
15.
go back to reference Perl TM, Dvorak L, Hwang T, Wenzel RP (1995) Long-term survival and function after suspected gram-negative sepsis. JAMA 274:338–345PubMed Perl TM, Dvorak L, Hwang T, Wenzel RP (1995) Long-term survival and function after suspected gram-negative sepsis. JAMA 274:338–345PubMed
16.
go back to reference Parno JR, Teres D, Lemeshow S, Brown RB (1982) Hospital charges and long-term survival of ICU versus non-ICU patients. Crit Care Med 10:569–574PubMed Parno JR, Teres D, Lemeshow S, Brown RB (1982) Hospital charges and long-term survival of ICU versus non-ICU patients. Crit Care Med 10:569–574PubMed
17.
go back to reference Thibault GE, Mulley AG, Barnett GO, Goldstein RL, Reder VA, Sherman EL, Skinner ER (1980) Medical intensive care: indications, interventions, and outcomes. N Engl J Med 302:938–942PubMed Thibault GE, Mulley AG, Barnett GO, Goldstein RL, Reder VA, Sherman EL, Skinner ER (1980) Medical intensive care: indications, interventions, and outcomes. N Engl J Med 302:938–942PubMed
18.
go back to reference Bams JL, Miranda DR (1985) Outcome and costs of intensive care: a follow-up study on 238 ICU-patients. Intensive Care Med 11:234–241PubMed Bams JL, Miranda DR (1985) Outcome and costs of intensive care: a follow-up study on 238 ICU-patients. Intensive Care Med 11:234–241PubMed
19.
go back to reference Jacobs CJ, van der Vliet JA, van Roozendaal MT, van der Linden CJ (1988) Mortality and quality of life after intensive care for critical illness. Intensive Care Med 14:217–220 Jacobs CJ, van der Vliet JA, van Roozendaal MT, van der Linden CJ (1988) Mortality and quality of life after intensive care for critical illness. Intensive Care Med 14:217–220
20.
go back to reference Mundt DJ, Gage RW, Lemeshow S, Pastides H, Teres D, Avrunin JS (1989) Intensive care unit patient follow-up. Mortality, functional status, and return to work at six months. Arch Intern Med 149:68–72 Mundt DJ, Gage RW, Lemeshow S, Pastides H, Teres D, Avrunin JS (1989) Intensive care unit patient follow-up. Mortality, functional status, and return to work at six months. Arch Intern Med 149:68–72
21.
go back to reference Ridley S, Jackson R, Findlay J, Wallace P (1990) Long term survival after intensive care. BMJ 301:1127–1130PubMed Ridley S, Jackson R, Findlay J, Wallace P (1990) Long term survival after intensive care. BMJ 301:1127–1130PubMed
22.
go back to reference Ridley S, Plenderleith L (1994) Survival after intensive care. Comparison with a matched normal population as an indicator of effectiveness. Anaesthesia 49:933–935PubMed Ridley S, Plenderleith L (1994) Survival after intensive care. Comparison with a matched normal population as an indicator of effectiveness. Anaesthesia 49:933–935PubMed
23.
go back to reference Niskanen M, Kari A, Halonen P (1996) Five-year survival after intensive care-comparison of 12:180 patients with the general population. Finnish ICU Study Group. Crit Care Med 24:1962–1967 Niskanen M, Kari A, Halonen P (1996) Five-year survival after intensive care-comparison of 12:180 patients with the general population. Finnish ICU Study Group. Crit Care Med 24:1962–1967
24.
go back to reference Capuzzo M, Bianconi M, Contu P, Pavoni V, Gritti G (1996) Survival and quality of life after intensive care. Intensive Care Med 22:947–953CrossRefPubMed Capuzzo M, Bianconi M, Contu P, Pavoni V, Gritti G (1996) Survival and quality of life after intensive care. Intensive Care Med 22:947–953CrossRefPubMed
25.
go back to reference Short TG, Buckley TA, Rowbottom MY, Wong E, Oh TE (1999) Long-term outcome and functional health status following intensive care in Hong Kong. Crit Care Med 27:51–57 Short TG, Buckley TA, Rowbottom MY, Wong E, Oh TE (1999) Long-term outcome and functional health status following intensive care in Hong Kong. Crit Care Med 27:51–57
26.
go back to reference Eddleston JM, White P, Guthrie E (2000) Survival, morbidity, and quality of life after discharge from intensive care. Crit Care Med 28:2293–2299 Eddleston JM, White P, Guthrie E (2000) Survival, morbidity, and quality of life after discharge from intensive care. Crit Care Med 28:2293–2299
27.
go back to reference Flaatten H, Kvale R (2001) Survival and quality of life 12 years after ICU. A comparison with the general Norwegian population. Intensive Care Med 27:1005–1011PubMed Flaatten H, Kvale R (2001) Survival and quality of life 12 years after ICU. A comparison with the general Norwegian population. Intensive Care Med 27:1005–1011PubMed
28.
go back to reference Montuclard L, Garrouste-Orgeas M, Timsit JF, Misset B, De Jonghe B, Carlet J (2000) Outcome, functional autonomy, and quality of life of elderly patients with a long-term intensive care unit stay. Crit Care Med 28:3389–3395 Montuclard L, Garrouste-Orgeas M, Timsit JF, Misset B, De Jonghe B, Carlet J (2000) Outcome, functional autonomy, and quality of life of elderly patients with a long-term intensive care unit stay. Crit Care Med 28:3389–3395
29.
go back to reference Tsevat J, Cook EF, Green ML, Matchar DB, Dawson NV, Broste SK, Wu AW, Phillips RS, Oye RK, Goldman L (1995) Health values of the seriously ill. SUPPORT investigators. Ann Intern Med 122:514–520PubMed Tsevat J, Cook EF, Green ML, Matchar DB, Dawson NV, Broste SK, Wu AW, Phillips RS, Oye RK, Goldman L (1995) Health values of the seriously ill. SUPPORT investigators. Ann Intern Med 122:514–520PubMed
30.
go back to reference McHugh LG, Milberg JA, Whitcomb ME, Schoene RB, Maunder RJ, Hudson LD (1994) Recovery of function in survivors of the acute respiratory distress syndrome. Am J Respir Crit Care Med 150:90–94 McHugh LG, Milberg JA, Whitcomb ME, Schoene RB, Maunder RJ, Hudson LD (1994) Recovery of function in survivors of the acute respiratory distress syndrome. Am J Respir Crit Care Med 150:90–94
31.
go back to reference Weinert CR, Gross CR, Kangas JR, Bury CL, Marinelli WA (1997) Health-related quality of life after acute lung injury. Am J Respir Crit Care Med 156:1120–1128 Weinert CR, Gross CR, Kangas JR, Bury CL, Marinelli WA (1997) Health-related quality of life after acute lung injury. Am J Respir Crit Care Med 156:1120–1128
32.
go back to reference Schelling G, Stoll C, Haller M, Briegel J, Manert W, Hummel T, Lenhart A, Heyduck M, Polasek J, Meier M, Preuss U, Bullinger M, Schuffel W, Peter K (1998) Health-related quality of life and posttraumatic stress disorder in survivors of the acute respiratory distress syndrome. Crit Care Med 26:651–659 Schelling G, Stoll C, Haller M, Briegel J, Manert W, Hummel T, Lenhart A, Heyduck M, Polasek J, Meier M, Preuss U, Bullinger M, Schuffel W, Peter K (1998) Health-related quality of life and posttraumatic stress disorder in survivors of the acute respiratory distress syndrome. Crit Care Med 26:651–659
33.
go back to reference Ely EW, Inouye SK, Bernard GR, Gordon S, Francis J, May L, Truman B, Speroff T, Gautam S, Margolin R, Hart RP, Dittus R (2001) Delirium in mechanically ventilated patients-Validity and reliability of the Confusion Assessment Method for the intensive care unit (CAM-ICU). JAMA 286:2703–2710PubMed Ely EW, Inouye SK, Bernard GR, Gordon S, Francis J, May L, Truman B, Speroff T, Gautam S, Margolin R, Hart RP, Dittus R (2001) Delirium in mechanically ventilated patients-Validity and reliability of the Confusion Assessment Method for the intensive care unit (CAM-ICU). JAMA 286:2703–2710PubMed
34.
go back to reference Hopkins RO, Weaver LK, Pope D, Orme JF, Bigler ED, Larson-Lohr V (1999) Neuropsychological sequelae and impaired health status in survivors of severe acute respiratory distress syndrome. Am J Respir Crit Care Med 160:50–56 Hopkins RO, Weaver LK, Pope D, Orme JF, Bigler ED, Larson-Lohr V (1999) Neuropsychological sequelae and impaired health status in survivors of severe acute respiratory distress syndrome. Am J Respir Crit Care Med 160:50–56
35.
go back to reference Hopkins RO, Gale SD, Pope D, Weaver LK, Bigler ED (2000) Ventricular enlargement in patients with acute respiratory distress syndrome (abstract). J Int Neuropsychol Soc 6:229 Hopkins RO, Gale SD, Pope D, Weaver LK, Bigler ED (2000) Ventricular enlargement in patients with acute respiratory distress syndrome (abstract). J Int Neuropsychol Soc 6:229
36.
go back to reference Hopkins RO (2001) Brain imaging, neurocognitive sequelae and health related quality of life following acute respiratory distress syndrome. In: SG Pandalai (ed) Recent research developments in respiratory and critical care medicine. Research Signpost, Kerala, pp 209–222 Hopkins RO (2001) Brain imaging, neurocognitive sequelae and health related quality of life following acute respiratory distress syndrome. In: SG Pandalai (ed) Recent research developments in respiratory and critical care medicine. Research Signpost, Kerala, pp 209–222
37.
38.
go back to reference Davidson TA, Caldwell ES, Curtis JR, Hudson LD, Steinberg KP (1999) Reduced quality of life in survivors of acute respiratory distress syndrome compared with critically ill control patients. JAMA 281:354–360PubMed Davidson TA, Caldwell ES, Curtis JR, Hudson LD, Steinberg KP (1999) Reduced quality of life in survivors of acute respiratory distress syndrome compared with critically ill control patients. JAMA 281:354–360PubMed
39.
go back to reference Woods NF, Haberman MR, Packard NJ (1993) Demands of illness and individual, dyadic, and family adaptation in chronic illness. West J Nurs Res 15:10–30PubMed Woods NF, Haberman MR, Packard NJ (1993) Demands of illness and individual, dyadic, and family adaptation in chronic illness. West J Nurs Res 15:10–30PubMed
40.
go back to reference Donelan K, Falik M, DesRoches CM (2001) Caregiving: challenges and implications for women's health. Womens Health Issues 11:185–200CrossRefPubMed Donelan K, Falik M, DesRoches CM (2001) Caregiving: challenges and implications for women's health. Womens Health Issues 11:185–200CrossRefPubMed
41.
go back to reference Angus DC (1997) Understanding the incidence and long-term outcome of ARDS. In: Gullo A (ed) Anaesthesia, pain, intensive care and emergency medicine: scientific report. Springer, Berlin Heidelberg New York, pp 289–298 Angus DC (1997) Understanding the incidence and long-term outcome of ARDS. In: Gullo A (ed) Anaesthesia, pain, intensive care and emergency medicine: scientific report. Springer, Berlin Heidelberg New York, pp 289–298
42.
go back to reference Pronovost PJ, Jencks M, Dorman T, Garrett E, Rosenfeld BA, Breslow MJ, Lipsett PA, Bass EB (1999) Organizational characteristics of intensive care units related to outcomes of abdominal aortic surgery. JAMA 281:1310–1312PubMed Pronovost PJ, Jencks M, Dorman T, Garrett E, Rosenfeld BA, Breslow MJ, Lipsett PA, Bass EB (1999) Organizational characteristics of intensive care units related to outcomes of abdominal aortic surgery. JAMA 281:1310–1312PubMed
43.
go back to reference Brown JJ, Sullivan G (1989) Effect on ICU mortality of a full-time critical care specialist. Chest 96:127–129PubMed Brown JJ, Sullivan G (1989) Effect on ICU mortality of a full-time critical care specialist. Chest 96:127–129PubMed
44.
go back to reference Baldock G, Foley P, Brett S (2001) The impact of organisational change on outcome in an intensive care unit in the United Kingdom. Intensive Care Med 27:865–872CrossRefPubMed Baldock G, Foley P, Brett S (2001) The impact of organisational change on outcome in an intensive care unit in the United Kingdom. Intensive Care Med 27:865–872CrossRefPubMed
45.
go back to reference Kuo HS, Tang GJ, Chuang JH, Lee CH, Lui WY, Lee TY, P'eng FK (2000) Changing ICU mortality in a decade-effect of full-time intensivist. Crit Care Shock 3:57–61 Kuo HS, Tang GJ, Chuang JH, Lee CH, Lui WY, Lee TY, P'eng FK (2000) Changing ICU mortality in a decade-effect of full-time intensivist. Crit Care Shock 3:57–61
46.
go back to reference Multz AS, Chalfin DB, Samson IM, Dantzker DR, Fein AM, Steinberg HN, Niederman MS, Scharf SM (1998) A "closed" medical intensive care unit (MICU) improves resource utilization when compared with an "open" MICU. Am J Respir Crit Care Med 157:1468–1473 Multz AS, Chalfin DB, Samson IM, Dantzker DR, Fein AM, Steinberg HN, Niederman MS, Scharf SM (1998) A "closed" medical intensive care unit (MICU) improves resource utilization when compared with an "open" MICU. Am J Respir Crit Care Med 157:1468–1473
47.
go back to reference Reynolds HN, Haupt MT, Thill-Baharozian MC, Carlson RW (1988) Impact of critical care physician staffing on patients with septic shock in a university hospital medical intensive care unit. JAMA 260:3446–3450PubMed Reynolds HN, Haupt MT, Thill-Baharozian MC, Carlson RW (1988) Impact of critical care physician staffing on patients with septic shock in a university hospital medical intensive care unit. JAMA 260:3446–3450PubMed
48.
go back to reference Al-Asadi L, Dellinger RP, Deutch J, Nathan SS (1996) Clinical impact of closed versus open provider care in a medical intensive care unit (abstract). Am J Respir Crit Care Med 153:A360 Al-Asadi L, Dellinger RP, Deutch J, Nathan SS (1996) Clinical impact of closed versus open provider care in a medical intensive care unit (abstract). Am J Respir Crit Care Med 153:A360
49.
go back to reference Carson SS, Stocking C, Podsadecki T, Christenson J, Pohlman A, MacRae S, Jordan J, Humphrey H, Siegler M, Hall J (1996) Effects of organizational change in the medical intensive care unit of a teaching hospital: a comparison of 'open' and 'closed' formats. JAMA 276:322–328PubMed Carson SS, Stocking C, Podsadecki T, Christenson J, Pohlman A, MacRae S, Jordan J, Humphrey H, Siegler M, Hall J (1996) Effects of organizational change in the medical intensive care unit of a teaching hospital: a comparison of 'open' and 'closed' formats. JAMA 276:322–328PubMed
50.
go back to reference Ghorra S, Reinert SE, Cioffi W, Buczko G, Simms HH (1999) Analysis of the effect of conversion from open to closed surgical intensive care unit. Ann Surg 229:163–171CrossRefPubMed Ghorra S, Reinert SE, Cioffi W, Buczko G, Simms HH (1999) Analysis of the effect of conversion from open to closed surgical intensive care unit. Ann Surg 229:163–171CrossRefPubMed
51.
go back to reference Li TC, Phillips MC, Shaw L, Cook EF, Natanson C, Goldman L (1984) On-site physician staffing in a community hospital intensive care unit. Impact on test and procedure use and on patient outcome. JAMA 252:2023–2027PubMed Li TC, Phillips MC, Shaw L, Cook EF, Natanson C, Goldman L (1984) On-site physician staffing in a community hospital intensive care unit. Impact on test and procedure use and on patient outcome. JAMA 252:2023–2027PubMed
52.
go back to reference Jacobs MC, Hussain E, Hanna A, Ruskin G, Weiss S, Skrzpiec W, Sison C, Cohn E (1998) Improving the outcome and efficiency of surgical intensive care: the impact of full time medical intensivists (abstract). Chest 114:276S-277S Jacobs MC, Hussain E, Hanna A, Ruskin G, Weiss S, Skrzpiec W, Sison C, Cohn E (1998) Improving the outcome and efficiency of surgical intensive care: the impact of full time medical intensivists (abstract). Chest 114:276S-277S
53.
go back to reference Manthous CA, Amoateng-Adjepong Y, al-Kharrat T, Jacob B, Alnuaimat HM, Chatila W, Hall JB (1997) Effects of a medical intensivist on patient care in a community teaching hospital. Mayo Clin Proc 72:391–399PubMed Manthous CA, Amoateng-Adjepong Y, al-Kharrat T, Jacob B, Alnuaimat HM, Chatila W, Hall JB (1997) Effects of a medical intensivist on patient care in a community teaching hospital. Mayo Clin Proc 72:391–399PubMed
54.
go back to reference Marini CP, Nathan IM, Ritter G, Rivera L, Jurkiewicz A, Cohen JR (1995) The impact of full-time surgical intensivists on ICU utilization and mortality (abstract). Crit Care Med 23:A235 Marini CP, Nathan IM, Ritter G, Rivera L, Jurkiewicz A, Cohen JR (1995) The impact of full-time surgical intensivists on ICU utilization and mortality (abstract). Crit Care Med 23:A235
55.
go back to reference Pollack MM, Katz RW, Ruttimann UE, Getson PR (1988) Improving the outcome and efficiency of intensive care: the impact of an intensivist. Crit Care Med 16:11–17 Pollack MM, Katz RW, Ruttimann UE, Getson PR (1988) Improving the outcome and efficiency of intensive care: the impact of an intensivist. Crit Care Med 16:11–17
56.
go back to reference Reich HS, Buhler L, David M, Whitmer G (1998) Saving lives in the community. Impact of intensive care leadership (abstract). Crit Care Med 25:A44 Reich HS, Buhler L, David M, Whitmer G (1998) Saving lives in the community. Impact of intensive care leadership (abstract). Crit Care Med 25:A44
57.
go back to reference Tai DYH, Goh SK, Eng PCT, Wang YT (1998) Impact on quality of patient care and procedure use in the medical intensive care unit (MICU) following reorganisation. Ann Acad Med Singapore 27:309–313PubMed Tai DYH, Goh SK, Eng PCT, Wang YT (1998) Impact on quality of patient care and procedure use in the medical intensive care unit (MICU) following reorganisation. Ann Acad Med Singapore 27:309–313PubMed
58.
go back to reference Pollack MM, Cuerdon TT, Patel KM, Ruttimann UE, Getson PR, Levetown M (1994) Impact of quality-of-care factors on pediatric intensive care unit mortality. JAMA 272:941–946PubMed Pollack MM, Cuerdon TT, Patel KM, Ruttimann UE, Getson PR, Levetown M (1994) Impact of quality-of-care factors on pediatric intensive care unit mortality. JAMA 272:941–946PubMed
59.
go back to reference DiCosmo BF (1999) Addition of an intensivist improves ICU outcomes in a non-teaching community hospital (abstract). Chest 116:238S DiCosmo BF (1999) Addition of an intensivist improves ICU outcomes in a non-teaching community hospital (abstract). Chest 116:238S
60.
go back to reference Dimick JB, Pronovost PJ, Heitmiller RF, Lipsett PA (2001) Intensive care unit physician staffing is associated with decreased length of stay, hospital cost, and complications after esophageal resection. Crit Care Med 29:753–758PubMed Dimick JB, Pronovost PJ, Heitmiller RF, Lipsett PA (2001) Intensive care unit physician staffing is associated with decreased length of stay, hospital cost, and complications after esophageal resection. Crit Care Med 29:753–758PubMed
61.
go back to reference Dimick JB, Pronovost PJ, Lipsett PA (2000) The effect of ICU physician staffing and hospital volume on outcomes after hepatic resection (abstract). Crit Care Med 28:A77 Dimick JB, Pronovost PJ, Lipsett PA (2000) The effect of ICU physician staffing and hospital volume on outcomes after hepatic resection (abstract). Crit Care Med 28:A77
62.
go back to reference Rosenfeld BA, Dorman T, Breslow MJ, Pronovost P, Jenckes M, Zhang N, Anderson G, Rubin H (2000) Intensive care unit telemedicine: alternate paradigm for providing continuous intensivist care. Crit Care Med 28:3925–3931PubMed Rosenfeld BA, Dorman T, Breslow MJ, Pronovost P, Jenckes M, Zhang N, Anderson G, Rubin H (2000) Intensive care unit telemedicine: alternate paradigm for providing continuous intensivist care. Crit Care Med 28:3925–3931PubMed
63.
go back to reference Diringer MN, Edwards DF (2001) Admission to a neurologic/neurosurgical intensive care unit is associated with reduced mortality rate after intracerebral hemorrhage. Crit Care Med 29:635–640PubMed Diringer MN, Edwards DF (2001) Admission to a neurologic/neurosurgical intensive care unit is associated with reduced mortality rate after intracerebral hemorrhage. Crit Care Med 29:635–640PubMed
64.
go back to reference Goh AYT, Lum LCS, Abdel-Latif MEA (2001) Impact of 24 hour critical care physician staffing on case-mix adjusted mortality in paediatric intensive care. Lancet 357:445–446PubMed Goh AYT, Lum LCS, Abdel-Latif MEA (2001) Impact of 24 hour critical care physician staffing on case-mix adjusted mortality in paediatric intensive care. Lancet 357:445–446PubMed
65.
go back to reference Blunt MC, Burchett KR (2000) Out-of-hours consultant cover and case-mix-adjusted mortality in intensive care. Lancet 356:735–736CrossRefPubMed Blunt MC, Burchett KR (2000) Out-of-hours consultant cover and case-mix-adjusted mortality in intensive care. Lancet 356:735–736CrossRefPubMed
66.
go back to reference Topeli A (2000) Effect of changing organization of intensive care unit from "open policy without critical care specialist" to "closed policy with critical care specialist" (abstract). Am J Respir Crit Care Med 161:A397 Topeli A (2000) Effect of changing organization of intensive care unit from "open policy without critical care specialist" to "closed policy with critical care specialist" (abstract). Am J Respir Crit Care Med 161:A397
67.
go back to reference Hanson CW, Deutschman CS, Anderson HL, Reilly PM, Behringer EC, Schwab CW, Price J (1999) Effects of an organized critical care service on outcomes and resource utilization: a cohort study. Crit Care Med 27:270–274 Hanson CW, Deutschman CS, Anderson HL, Reilly PM, Behringer EC, Schwab CW, Price J (1999) Effects of an organized critical care service on outcomes and resource utilization: a cohort study. Crit Care Med 27:270–274
68.
go back to reference Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ Jr, for the PROWESS Study Group (2001) Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 344:699–709PubMed Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ Jr, for the PROWESS Study Group (2001) Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 344:699–709PubMed
69.
go back to reference Kress JP, Pohlman AS, O'Connor MF, Hall JB (2000) Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med 342:1471–1477PubMed Kress JP, Pohlman AS, O'Connor MF, Hall JB (2000) Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med 342:1471–1477PubMed
70.
go back to reference Ely EW, Baker AM, Dunagan DP, Burke HL, Smith AC, Kelly PT, Johnson MM, Browder RW, Bowton DL, Haponik EF (1996) Effect on the duration of mechanical ventilation of identifying patients capable of breathing spontaneously. N Engl J Med 335:1864–1869PubMed Ely EW, Baker AM, Dunagan DP, Burke HL, Smith AC, Kelly PT, Johnson MM, Browder RW, Bowton DL, Haponik EF (1996) Effect on the duration of mechanical ventilation of identifying patients capable of breathing spontaneously. N Engl J Med 335:1864–1869PubMed
71.
go back to reference Hebert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, Tweeddale M, Schweitzer I, Yetisir E (1999) A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med 340:409–417 Hebert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, Tweeddale M, Schweitzer I, Yetisir E (1999) A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. N Engl J Med 340:409–417
72.
go back to reference Clermont G, Angus DC, Linde-Zwirble WT, Griffin MF, Fine MJ, Pinsky MR (2002) Does acute organ dysfunction predict patient-centered outcomes? Chest 121:1963–1971PubMed Clermont G, Angus DC, Linde-Zwirble WT, Griffin MF, Fine MJ, Pinsky MR (2002) Does acute organ dysfunction predict patient-centered outcomes? Chest 121:1963–1971PubMed
73.
go back to reference Heyland DK, Guyatt G, Cook DJ, Meade M, Juniper E, Cronin L, Gafni A (1998) Frequency and methodologic rigor of quality-of-life assessments in the critical care literature. Crit Care Med 26:591–598PubMed Heyland DK, Guyatt G, Cook DJ, Meade M, Juniper E, Cronin L, Gafni A (1998) Frequency and methodologic rigor of quality-of-life assessments in the critical care literature. Crit Care Med 26:591–598PubMed
74.
go back to reference Black NA, Jenkinson C, Hayes JA, Young D, Vella K, Rowan KM, Daly K, Ridley S (2001) Review of outcome measures used in adult critical care. Crit Care Med 29:2119–2124PubMed Black NA, Jenkinson C, Hayes JA, Young D, Vella K, Rowan KM, Daly K, Ridley S (2001) Review of outcome measures used in adult critical care. Crit Care Med 29:2119–2124PubMed
75.
go back to reference Rothenhausler HB, Ehrentraut S, Stoll C, Schelling G, Kapfhammer HP (2001) The relationship between cognitive performance and employment and health status in long-term survivors of the acute respiratory distress syndrome: results of an exploratory study. Gen Hosp Psychiatry 23:88–94 Rothenhausler HB, Ehrentraut S, Stoll C, Schelling G, Kapfhammer HP (2001) The relationship between cognitive performance and employment and health status in long-term survivors of the acute respiratory distress syndrome: results of an exploratory study. Gen Hosp Psychiatry 23:88–94
76.
go back to reference Marquis KA, Curtis JR, Caldwel ES, et al (2000) Neuropsychologic sequelae in survivors of ARDS compared with critically ill control patients (abstract). Am J Respir Crit Care Med 16:A383 Marquis KA, Curtis JR, Caldwel ES, et al (2000) Neuropsychologic sequelae in survivors of ARDS compared with critically ill control patients (abstract). Am J Respir Crit Care Med 16:A383
77.
go back to reference Hopkins RO (2002) How should we assess neuropsychological sequelae of critical illness? In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York Hopkins RO (2002) How should we assess neuropsychological sequelae of critical illness? In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
78.
go back to reference van Hout B, Angus DC (2002) How should we measure the economic consequences of critical illness? In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York van Hout B, Angus DC (2002) How should we measure the economic consequences of critical illness? In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
79.
go back to reference Cohen J, Guyatt G, Bernard GR, Calandra T, Cook D, Elbourne D, Marshall J, Nunn A, Opal S, on behalf of a UK Medical Research Council International Working Party (2001) New strategies for clinical trials in patients with sepsis and septic shock. Crit Care Med 29:880–886PubMed Cohen J, Guyatt G, Bernard GR, Calandra T, Cook D, Elbourne D, Marshall J, Nunn A, Opal S, on behalf of a UK Medical Research Council International Working Party (2001) New strategies for clinical trials in patients with sepsis and septic shock. Crit Care Med 29:880–886PubMed
80.
go back to reference Curtis JR (2002) Measuring health status after critical illness: where are we and where do we go from here? In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York Curtis JR (2002) Measuring health status after critical illness: where are we and where do we go from here? In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
81.
go back to reference Angus DC, Rubenfeld GD, Roberts MS, Curtis JR, Connors AFJ, Cook DJ, Lave JR, Pinsky MR (2002) Understanding costs and cost-effectiveness in critical care: report from the Second American Thoracic Society Workshop on Outcomes Research. Am J Respir Crit Care Med 165:540–550PubMed Angus DC, Rubenfeld GD, Roberts MS, Curtis JR, Connors AFJ, Cook DJ, Lave JR, Pinsky MR (2002) Understanding costs and cost-effectiveness in critical care: report from the Second American Thoracic Society Workshop on Outcomes Research. Am J Respir Crit Care Med 165:540–550PubMed
82.
go back to reference Rubenfeld GD, Angus DC, Pinsky MR, Curtis JR, Connors AFJ, Bernard GR, and the members of the Outcomes Research Workshop (1999) Outcomes research in critical care: results of the American Thoracic Society Critical Care Assembly Workshop on Outcomes Research. Am J Respir Crit Care Med 160:358–367PubMed Rubenfeld GD, Angus DC, Pinsky MR, Curtis JR, Connors AFJ, Bernard GR, and the members of the Outcomes Research Workshop (1999) Outcomes research in critical care: results of the American Thoracic Society Critical Care Assembly Workshop on Outcomes Research. Am J Respir Crit Care Med 160:358–367PubMed
83.
go back to reference Ware JE Jr, Sherbourne CD (1992) The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 30:473–483PubMed Ware JE Jr, Sherbourne CD (1992) The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 30:473–483PubMed
84.
go back to reference The EuroQol Group (1990) EuroQol—a new facility for the measurement of health-related quality of life. Health Policy 16:199–208PubMed The EuroQol Group (1990) EuroQol—a new facility for the measurement of health-related quality of life. Health Policy 16:199–208PubMed
85.
go back to reference Gold MR, Russell LB, Seigel JE, Weinstein MC (1996) Cost-effectiveness in health and medicine. Oxford University Press, New York Gold MR, Russell LB, Seigel JE, Weinstein MC (1996) Cost-effectiveness in health and medicine. Oxford University Press, New York
86.
go back to reference Brazier J, Roberts J, Deverill M (2002) The estimation of a preference-based measure of health from the SF-36. J Health Econ 21:271–292CrossRefPubMed Brazier J, Roberts J, Deverill M (2002) The estimation of a preference-based measure of health from the SF-36. J Health Econ 21:271–292CrossRefPubMed
87.
go back to reference McMullin J, Cook DJ (2002) Changing ICU behavior to focus on long-term outcomes. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York McMullin J, Cook DJ (2002) Changing ICU behavior to focus on long-term outcomes. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
88.
go back to reference Young C, Millo JL, Salmon J (2002) Reduction in post-ICU, in-hospital mortality following the introduction of an ICU nursing outreach service (abstract). Critical Care 6 [Suppl 1]:S117 Young C, Millo JL, Salmon J (2002) Reduction in post-ICU, in-hospital mortality following the introduction of an ICU nursing outreach service (abstract). Critical Care 6 [Suppl 1]:S117
89.
go back to reference Pronovost P, Wu A, Holzmueller CG (2002) Defining success in ICU care. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York Pronovost P, Wu A, Holzmueller CG (2002) Defining success in ICU care. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
90.
go back to reference Hartleib M, Sibbald WJ (2002) Re-organizing health care systems to optimize critical care outcomes. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York Hartleib M, Sibbald WJ (2002) Re-organizing health care systems to optimize critical care outcomes. In: DC Angus, J Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39. Springer, Berlin Heidelberg New York
91.
go back to reference Rubenfeld GD et al. (2003) Surrogate measures of patient-centered outcomes. In: Angus, Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39 Rubenfeld GD et al. (2003) Surrogate measures of patient-centered outcomes. In: Angus, Carlet (eds) Surviving intensive care. Update in intensive care and emergency medicine, no 39
92.
go back to reference Packer M (1992) Effect of oral milrinone on mortality in severe chronic heart-failure. Verh Dtsch Ges Herz Kreislaufforsch 24:276 Packer M (1992) Effect of oral milrinone on mortality in severe chronic heart-failure. Verh Dtsch Ges Herz Kreislaufforsch 24:276
93.
go back to reference Echt DS, Liebson PR, Mitchell LB, Peters RW, Obias-Manno D, Barker AH, Arensberg D, Baker A, Friedman L, Greene HL (1991) Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med 324:781–788 Echt DS, Liebson PR, Mitchell LB, Peters RW, Obias-Manno D, Barker AH, Arensberg D, Baker A, Friedman L, Greene HL (1991) Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med 324:781–788
94.
go back to reference Takala J, Ruokonen E, Webster NR, Nielsen MS, Zandstra DF, Vundelinckx G, Hinds CJ (1999) Increased mortality associated with growth hormone treatment in critically ill adults. N Engl J Med 341:785–792 Takala J, Ruokonen E, Webster NR, Nielsen MS, Zandstra DF, Vundelinckx G, Hinds CJ (1999) Increased mortality associated with growth hormone treatment in critically ill adults. N Engl J Med 341:785–792
95.
go back to reference Garland JS, Alex CP, Pauly TH, Whitehead VL, Brand J, Winston JF, Samuels DP, McAuliffe TL (1999) A three-day course of dexamethasone therapy to prevent chronic lung disease in ventilated neonates: a randomized trial. Pediatrics 104:91–99PubMed Garland JS, Alex CP, Pauly TH, Whitehead VL, Brand J, Winston JF, Samuels DP, McAuliffe TL (1999) A three-day course of dexamethasone therapy to prevent chronic lung disease in ventilated neonates: a randomized trial. Pediatrics 104:91–99PubMed
96.
go back to reference Taylor HG, Klein N, Hack M (2000) School-age consequences of birth weight less than 750 g: a review and update. Dev Neuropsychol 17:289–321PubMed Taylor HG, Klein N, Hack M (2000) School-age consequences of birth weight less than 750 g: a review and update. Dev Neuropsychol 17:289–321PubMed
97.
go back to reference O'Shea TM, Kothadia JM, Klinepeter KL, Goldstein DJ, Jackson BG, Weaver RG, Dillard RG (1999) Randomized placebo-controlled trial of a 42-day tapering course of dexamethasone to reduce the duration of ventilator dependency in very low birth weight infants: outcome of study participants at 1-year adjusted age. Pediatrics 104:15–21PubMed O'Shea TM, Kothadia JM, Klinepeter KL, Goldstein DJ, Jackson BG, Weaver RG, Dillard RG (1999) Randomized placebo-controlled trial of a 42-day tapering course of dexamethasone to reduce the duration of ventilator dependency in very low birth weight infants: outcome of study participants at 1-year adjusted age. Pediatrics 104:15–21PubMed
Metadata
Title
Surviving Intensive Care: a report from the 2002 Brussels Roundtable
Authors
Derek C. Angus
Jean Carlet
on behalf of the 2002 Brussels Roundtable Participants
Publication date
01-03-2003
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 3/2003
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-002-1624-8

Other articles of this Issue 3/2003

Intensive Care Medicine 3/2003 Go to the issue