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Published in: Social Psychiatry and Psychiatric Epidemiology 5/2015

01-05-2015 | Original Paper

Trends in the dispensation of antidepressant drugs over the past decade (2000–2010) in Andalusia, Spain

Authors: M. C. González-López, C. M. Rodríguez-López, T. Parrón-Carreño, J. D. Luna, E. Del Pozo

Published in: Social Psychiatry and Psychiatric Epidemiology | Issue 5/2015

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Abstract

Purpose

To study antidepressant drug dispensation in the Spanish region of Andalusia and in the Almeria Health Area (AHA) over the past decade, analyzing the variability, trends, and influential factors.

Methods

We conducted an observational ecological study of antidepressant drug dispensation between 2000 and 2010 in Andalusia. Dispensation was measured as Defined Daily Dose (DDD) per 1,000 inhabitants per day. A multilevel analysis (STATA 11.1) was performed to determine the variability among the basic health zones (BHZs) (2004–2010) and influential factors.

Results

Between 2000 and 2010, the total dispensation of antidepressant drugs increased by more than 100 % in Andalusia and in the AHA. This increase was primarily caused by the greater dispensation of selective serotonin reuptake inhibitors (ATC-N06AB) and other antidepressants (ATC-N06AX). Multilevel analysis revealed a wide variability in the levels and trends of antidepressant dispensation among BHZs. Urbanicity and the percentage of immigrants in the BHZ were negatively associated with their dispensation, which was positively influenced by a higher proportion of women and over 65-year-olds in the population.

Conclusions

The elevated dispensation of several groups of antidepressant drugs in this study population indicates the need for health policies to rationalize their use. Further research is required into the differences in antidepressant dispensations between immigrant and native populations and the implications for public health policies.
Literature
1.
go back to reference Alonso J, Angermeyer MC, Bernert S, Bruffaerts R, Brugha TS, Bryson H, de Girolamo G, Graaf R, Demyttenaere K, Gasquet I, Haro JM, Katz SJ, Kessler RC, Kovess V, Lépine JP, Ormel J, Polidori G, Russo LJ, Vilagut G, Almansa J, Arbabzadeh-Bouchez S, Autonell J, Bernal M, Buist-Bouwman MA, Codony M, Domingo-Salvany A, Ferrer M, Joo SS, Martínez-Alonso M, Matschinger H, Mazzi F, Morgan Z, Morosini P, Palacín C, Romera B, Taub N, Vollebergh WA; ESEMeD/MHEDEA 2000 Investigators, European Study of the Epidemiology of Mental Disorders (ESEMeD) Project (2004) Disability and quality of life impact of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand 109(Suppl 420):38–46 Alonso J, Angermeyer MC, Bernert S, Bruffaerts R, Brugha TS, Bryson H, de Girolamo G, Graaf R, Demyttenaere K, Gasquet I, Haro JM, Katz SJ, Kessler RC, Kovess V, Lépine JP, Ormel J, Polidori G, Russo LJ, Vilagut G, Almansa J, Arbabzadeh-Bouchez S, Autonell J, Bernal M, Buist-Bouwman MA, Codony M, Domingo-Salvany A, Ferrer M, Joo SS, Martínez-Alonso M, Matschinger H, Mazzi F, Morgan Z, Morosini P, Palacín C, Romera B, Taub N, Vollebergh WA; ESEMeD/MHEDEA 2000 Investigators, European Study of the Epidemiology of Mental Disorders (ESEMeD) Project (2004) Disability and quality of life impact of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand 109(Suppl 420):38–46
2.
go back to reference Alonso J, Angermeyer MC, Bernert S, Bruffaerts R, Brugha TS, Bryson H, de Girolamo G, Graaf R, Demyttenaere K, Gasquet I, Haro JM, Katz SJ, Kessler RC, Kovess V, Lépine JP, Ormel J, Polidori G, Russo LJ, Vilagut G, Almansa J, Arbabzadeh-Bouchez S, Autonell J, Bernal M, Buist-Bouwman MA, Codony M, Domingo-Salvany A, Ferrer M, Joo SS, Martínez-Alonso M, Matschinger H, Mazzi F, Morgan Z, Morosini P, Palacín C, Romera B, Taub N, Vollebergh WA; ESEMeD/MHEDEA 2000 Investigators (2004) Use of mental health services in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand 109(Suppl 420):47–54 Alonso J, Angermeyer MC, Bernert S, Bruffaerts R, Brugha TS, Bryson H, de Girolamo G, Graaf R, Demyttenaere K, Gasquet I, Haro JM, Katz SJ, Kessler RC, Kovess V, Lépine JP, Ormel J, Polidori G, Russo LJ, Vilagut G, Almansa J, Arbabzadeh-Bouchez S, Autonell J, Bernal M, Buist-Bouwman MA, Codony M, Domingo-Salvany A, Ferrer M, Joo SS, Martínez-Alonso M, Matschinger H, Mazzi F, Morgan Z, Morosini P, Palacín C, Romera B, Taub N, Vollebergh WA; ESEMeD/MHEDEA 2000 Investigators (2004) Use of mental health services in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand 109(Suppl 420):47–54
3.
go back to reference Serrano-Blanco A, Palao DJ, Luciano JV, Pinto-Meza A, Luján L, Fernández A, Roura P, Bertsch J, Mercader M, Haro JM (2010) Prevalence of mental disorders in primary care: results from the diagnosis and treatment of mental disorders in primary care study (DASMAP). Soc Psychiatry Psychiatr Epidemiol 45:201–210CrossRefPubMed Serrano-Blanco A, Palao DJ, Luciano JV, Pinto-Meza A, Luján L, Fernández A, Roura P, Bertsch J, Mercader M, Haro JM (2010) Prevalence of mental disorders in primary care: results from the diagnosis and treatment of mental disorders in primary care study (DASMAP). Soc Psychiatry Psychiatr Epidemiol 45:201–210CrossRefPubMed
4.
go back to reference Hernandez JF, Mantel-Teeuwisse AK, van Thiel GJ, Belitser SV, Warmerdam J, de Valk V, Raaijmakers JA, Pieters T (2012) A 10-year analysis of the effects of media coverage of regulatory warnings on antidepressant use in The Netherlands and UK. PLoS ONE 7:e45515CrossRefPubMedCentralPubMed Hernandez JF, Mantel-Teeuwisse AK, van Thiel GJ, Belitser SV, Warmerdam J, de Valk V, Raaijmakers JA, Pieters T (2012) A 10-year analysis of the effects of media coverage of regulatory warnings on antidepressant use in The Netherlands and UK. PLoS ONE 7:e45515CrossRefPubMedCentralPubMed
5.
go back to reference National Institute for Clinical Excellence (2007) Depression: management of depression in primary and secondary care. London: NICE, (National Clinical Practice Guideline No 23 amended) National Institute for Clinical Excellence (2007) Depression: management of depression in primary and secondary care. London: NICE, (National Clinical Practice Guideline No 23 amended)
6.
go back to reference Broich K (2009) Committee for medicinal products for human use (CHMP) assessment on efficacy of antidepressants. Eur Neuropsychopharmacol 19:305–308CrossRefPubMed Broich K (2009) Committee for medicinal products for human use (CHMP) assessment on efficacy of antidepressants. Eur Neuropsychopharmacol 19:305–308CrossRefPubMed
7.
go back to reference Hegerl U, Allgaier AK, Henkel V, Mergl R (2012) Can effects of antidepressants in patients with mild depression be considered as clinically significant? J Affect Disord 138:183–191CrossRefPubMed Hegerl U, Allgaier AK, Henkel V, Mergl R (2012) Can effects of antidepressants in patients with mild depression be considered as clinically significant? J Affect Disord 138:183–191CrossRefPubMed
8.
go back to reference Serna C, Cruz I, Galván L, Real J, Gascó E, Soler-González J (2010) Evolution of the prevalence and incidence of consumption of antidepressants in a Spanish region (2002–2007). Ment Health Fam Med 7:9–15PubMedCentralPubMed Serna C, Cruz I, Galván L, Real J, Gascó E, Soler-González J (2010) Evolution of the prevalence and incidence of consumption of antidepressants in a Spanish region (2002–2007). Ment Health Fam Med 7:9–15PubMedCentralPubMed
9.
go back to reference Alonso J, Angermeyer MC, Bernert S, Bruffaerts R, Brugha TS, Bryson H, de Girolamo G, Graaf R, Demyttenaere K, Gasquet I, Haro JM, Katz SJ, Kessler RC, Kovess V, Lépine JP, Ormel J, Polidori G, Russo LJ, Vilagut G, Almansa J, Arbabzadeh-Bouchez S, Autonell J, Bernal M, Buist-Bouwman MA, Codony M, Domingo-Salvany A, Ferrer M, Joo SS, Martínez-Alonso M, Matschinger H, Mazzi F, Morgan Z, Morosini P, Palacín C, Romera B, Taub N, Vollebergh WA; ESEMeD/MHEDEA 2000 Investigators, European Study of the Epidemiology of Mental Disorders (ESEMeD) Project (2004) Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand 109(Suppl 420):21–27 Alonso J, Angermeyer MC, Bernert S, Bruffaerts R, Brugha TS, Bryson H, de Girolamo G, Graaf R, Demyttenaere K, Gasquet I, Haro JM, Katz SJ, Kessler RC, Kovess V, Lépine JP, Ormel J, Polidori G, Russo LJ, Vilagut G, Almansa J, Arbabzadeh-Bouchez S, Autonell J, Bernal M, Buist-Bouwman MA, Codony M, Domingo-Salvany A, Ferrer M, Joo SS, Martínez-Alonso M, Matschinger H, Mazzi F, Morgan Z, Morosini P, Palacín C, Romera B, Taub N, Vollebergh WA; ESEMeD/MHEDEA 2000 Investigators, European Study of the Epidemiology of Mental Disorders (ESEMeD) Project (2004) Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand 109(Suppl 420):21–27
10.
go back to reference Dumesnil H, Cortaredona S, Verdoux H, Sebbah R, Paraponaris A, Verger P (2012) General practitioners’ choices and their determinants when starting treatment for major depression: a cross sectional, randomized case-vignette survey. PLoS ONE 7(12):e52429CrossRefPubMedCentralPubMed Dumesnil H, Cortaredona S, Verdoux H, Sebbah R, Paraponaris A, Verger P (2012) General practitioners’ choices and their determinants when starting treatment for major depression: a cross sectional, randomized case-vignette survey. PLoS ONE 7(12):e52429CrossRefPubMedCentralPubMed
11.
go back to reference Morrison J, Anderson MJ, Sutton M, Munoz-Arroyo R, McDonald S, Maxwell M, Power A, Smith M, Wilson P (2009) Factors influencing variation in prescribing of antidepressants by general practices in Scotland. Br J Gen Pract 59(559):e25–e31CrossRefPubMedCentralPubMed Morrison J, Anderson MJ, Sutton M, Munoz-Arroyo R, McDonald S, Maxwell M, Power A, Smith M, Wilson P (2009) Factors influencing variation in prescribing of antidepressants by general practices in Scotland. Br J Gen Pract 59(559):e25–e31CrossRefPubMedCentralPubMed
12.
go back to reference Wittkampf LC, Smeets HM, Knol MJ, Geerlings MI, Braam AW, De Wit NJ (2009) Differences in psychotropic drug prescriptions among ethnic groups in the Netherlands. Soc Psychiatry Psychiatr Epidemiol 45:819–826CrossRefPubMed Wittkampf LC, Smeets HM, Knol MJ, Geerlings MI, Braam AW, De Wit NJ (2009) Differences in psychotropic drug prescriptions among ethnic groups in the Netherlands. Soc Psychiatry Psychiatr Epidemiol 45:819–826CrossRefPubMed
13.
go back to reference Hull SA, Cornwell J, Harvey C, Eldridge S, Bare PO (2001) Prescribing rates for psychotropic medication amongst east London general practices: low rates where Asian populations are greatest. Fam Pract 18:167–173CrossRefPubMed Hull SA, Cornwell J, Harvey C, Eldridge S, Bare PO (2001) Prescribing rates for psychotropic medication amongst east London general practices: low rates where Asian populations are greatest. Fam Pract 18:167–173CrossRefPubMed
14.
go back to reference Spanish Statistica l Office (2010) The statistical information INE. Demography and population. Annual report 2010 Spanish Statistica l Office (2010) The statistical information INE. Demography and population. Annual report 2010
15.
16.
go back to reference Parabiaghi A, Franchi C, Tettamanti M, Barbato A, D’Avanzo B, Fortino I, Bortolotti A, Merlino L, Nobili A (2011) Antidepressants utilization among elderly in Lombardy from 2000 to 2007: dispensing trends and appropriateness. Eur J Clin Pharmacol 67:1077–1083CrossRefPubMed Parabiaghi A, Franchi C, Tettamanti M, Barbato A, D’Avanzo B, Fortino I, Bortolotti A, Merlino L, Nobili A (2011) Antidepressants utilization among elderly in Lombardy from 2000 to 2007: dispensing trends and appropriateness. Eur J Clin Pharmacol 67:1077–1083CrossRefPubMed
17.
go back to reference Ilyas S, Moncrieff J (2012) Trends in prescriptions and costs of drugs for mental disorders in England, 1998–2010. Br J Psychiatry 200:393–398CrossRefPubMed Ilyas S, Moncrieff J (2012) Trends in prescriptions and costs of drugs for mental disorders in England, 1998–2010. Br J Psychiatry 200:393–398CrossRefPubMed
18.
go back to reference Vedia-Urgell C, Bonet Monne S, Forcada Vega C, Parellada Esquius N (2005) Study of use of psychiatric drugs in primary care. Aten Primaria 36:239–245CrossRefPubMed Vedia-Urgell C, Bonet Monne S, Forcada Vega C, Parellada Esquius N (2005) Study of use of psychiatric drugs in primary care. Aten Primaria 36:239–245CrossRefPubMed
19.
go back to reference Arias LH, Lobato CT, Ortega S, Velasco A, Carvajal A, del Pozo JG (2010) Trends in the consumption of antidepressants in Castilla y León (Spain). Association between suicide rates and antidepressant drug consumption. Pharmacoepidemiol Drug Saf 19:895–900CrossRefPubMed Arias LH, Lobato CT, Ortega S, Velasco A, Carvajal A, del Pozo JG (2010) Trends in the consumption of antidepressants in Castilla y León (Spain). Association between suicide rates and antidepressant drug consumption. Pharmacoepidemiol Drug Saf 19:895–900CrossRefPubMed
20.
go back to reference Omori IM, Watanabe N, Nakagawa A, Cipriani A, Barbui C, McGuire H, Churchill R, Furukawa TA (2010) Fluvoxamine versus other anti-depressive agents for depression. Cochrane Database Syst Rev 17(3):CD006114 Omori IM, Watanabe N, Nakagawa A, Cipriani A, Barbui C, McGuire H, Churchill R, Furukawa TA (2010) Fluvoxamine versus other anti-depressive agents for depression. Cochrane Database Syst Rev 17(3):CD006114
21.
go back to reference Ramsberg J, Asseburg C, Henriksson M (2012) Effectiveness and cost-effectiveness of antidepressants in primary care: a multiple treatment comparison meta-analysis and cost-effectiveness model. PLoS ONE 7(8):e42003CrossRefPubMedCentralPubMed Ramsberg J, Asseburg C, Henriksson M (2012) Effectiveness and cost-effectiveness of antidepressants in primary care: a multiple treatment comparison meta-analysis and cost-effectiveness model. PLoS ONE 7(8):e42003CrossRefPubMedCentralPubMed
22.
go back to reference Aguglia E, Ravasio R, Simonetti M, Pecchioli S, Mazzoleni F (2012) Use and treatment modalities for SSRI and SNRI antidepressants in Italy during the period 2003–2009. Curr Med Res Opin 28:1475–1484CrossRefPubMed Aguglia E, Ravasio R, Simonetti M, Pecchioli S, Mazzoleni F (2012) Use and treatment modalities for SSRI and SNRI antidepressants in Italy during the period 2003–2009. Curr Med Res Opin 28:1475–1484CrossRefPubMed
23.
go back to reference Cipriani A, Furukawa TA, Salanti G, Geddes JR, Higgins JP, Churchill R, Watanabe N, Nakagawa A, Omori IM, McGuire H, Tansella M, Barbui C (2009) Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis. Lancet 373(9665):746–758CrossRefPubMed Cipriani A, Furukawa TA, Salanti G, Geddes JR, Higgins JP, Churchill R, Watanabe N, Nakagawa A, Omori IM, McGuire H, Tansella M, Barbui C (2009) Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis. Lancet 373(9665):746–758CrossRefPubMed
24.
go back to reference Eyding D, Lelgemann M, Grouven U, Härter M, Kromp M, Kaiser T, Kerekes MF, Gerken M, Wieseler B (2010) Reboxetine for acute treatment of major depression: systematic review and meta-analysis of published and unpublished placebo and selective serotonin reuptake inhibitor controlled trials. BMJ 341:c4737CrossRefPubMedCentralPubMed Eyding D, Lelgemann M, Grouven U, Härter M, Kromp M, Kaiser T, Kerekes MF, Gerken M, Wieseler B (2010) Reboxetine for acute treatment of major depression: systematic review and meta-analysis of published and unpublished placebo and selective serotonin reuptake inhibitor controlled trials. BMJ 341:c4737CrossRefPubMedCentralPubMed
25.
go back to reference Lockhart P, Guthrie B (2011) Trends in primary care antidepressant prescribing 1995–2007: a longitudinal population database analysis. Br J Gen Pract 61:e565–e572CrossRefPubMedCentralPubMed Lockhart P, Guthrie B (2011) Trends in primary care antidepressant prescribing 1995–2007: a longitudinal population database analysis. Br J Gen Pract 61:e565–e572CrossRefPubMedCentralPubMed
26.
go back to reference Haro JM, Palacín C, Vilagut G, Martínez M, Bernal M, Luque I, Codony M, Dolz M, Alonso J, Grupo ESEMeD-España (2006) Prevalence of mental disorders and associated factors: results from the ESEMeD-Spain study. Med Clin (Barc) 126: 445–451 Haro JM, Palacín C, Vilagut G, Martínez M, Bernal M, Luque I, Codony M, Dolz M, Alonso J, Grupo ESEMeD-España (2006) Prevalence of mental disorders and associated factors: results from the ESEMeD-Spain study. Med Clin (Barc) 126: 445–451
27.
go back to reference Gabilondo A, Rojas-Farreras S, Vilagut G, Haro JM, Fernández A, Pinto-Meza A, Alonso J (2010) Epidemiology of major depressive episode in a southern European country: results from the ESEMeD-Spain project. J Affect Disord 120:76–85CrossRefPubMedCentralPubMed Gabilondo A, Rojas-Farreras S, Vilagut G, Haro JM, Fernández A, Pinto-Meza A, Alonso J (2010) Epidemiology of major depressive episode in a southern European country: results from the ESEMeD-Spain project. J Affect Disord 120:76–85CrossRefPubMedCentralPubMed
28.
go back to reference Moore M, Yuen HM, Dunn N, Mullee MA, Maskell J, Kendrick T (2009) Explaining the rise in antidepressant prescribing: a descriptive study using the general practice research database. BMJ 339:b3999CrossRefPubMedCentralPubMed Moore M, Yuen HM, Dunn N, Mullee MA, Maskell J, Kendrick T (2009) Explaining the rise in antidepressant prescribing: a descriptive study using the general practice research database. BMJ 339:b3999CrossRefPubMedCentralPubMed
29.
go back to reference Cascade EF, Kalali AH, Thase ME (2007) Use of antidepressants: expansion beyond depression and anxiety. Psychiatry (Edgmont) 4:25–28 Cascade EF, Kalali AH, Thase ME (2007) Use of antidepressants: expansion beyond depression and anxiety. Psychiatry (Edgmont) 4:25–28
30.
go back to reference Mercier A, Auger-Aubin I, Lebeau JP, Schuers M, Boulet P, Hermil JL, Van Royen P, Peremans L (2013) Evidence of prescription of antidepressants for non-psychiatric conditions in primary care: an analysis of guidelines and systematic reviews. BMC Fam Pract 14:55CrossRefPubMedCentralPubMed Mercier A, Auger-Aubin I, Lebeau JP, Schuers M, Boulet P, Hermil JL, Van Royen P, Peremans L (2013) Evidence of prescription of antidepressants for non-psychiatric conditions in primary care: an analysis of guidelines and systematic reviews. BMC Fam Pract 14:55CrossRefPubMedCentralPubMed
31.
go back to reference Pagura J, Katz LY, Mojtabai R, Druss BG, Cox B, Sareen J (2011) Antidepressant use in the absence of common mental disorders in the general population. J Clin Psychiatry 72:494–501CrossRefPubMed Pagura J, Katz LY, Mojtabai R, Druss BG, Cox B, Sareen J (2011) Antidepressant use in the absence of common mental disorders in the general population. J Clin Psychiatry 72:494–501CrossRefPubMed
32.
go back to reference Mykletun A, Knudsen AK, Tangen T, Overland S (2010) General practitioners’ opinions on how to improve treatment of mental disorders in primary health care. Interviews with one hundred Norwegian general practitioners. BMC Health Serv Res 10:35CrossRefPubMedCentralPubMed Mykletun A, Knudsen AK, Tangen T, Overland S (2010) General practitioners’ opinions on how to improve treatment of mental disorders in primary health care. Interviews with one hundred Norwegian general practitioners. BMC Health Serv Res 10:35CrossRefPubMedCentralPubMed
33.
go back to reference Mojtabai R (2014) Diagnosing depression in older adults in primary care. N Engl J Med 370:1180–1182CrossRefPubMed Mojtabai R (2014) Diagnosing depression in older adults in primary care. N Engl J Med 370:1180–1182CrossRefPubMed
34.
go back to reference Ivanova JI, Bienfait-Beuzon C, Birnbaum HG, Connolly C, Emani S, Sheehy M (2011) Physicians’ decisions to prescribe antidepressant therapy in older patients with depression in a US managed care plan. Drugs Aging 28:51–62CrossRefPubMed Ivanova JI, Bienfait-Beuzon C, Birnbaum HG, Connolly C, Emani S, Sheehy M (2011) Physicians’ decisions to prescribe antidepressant therapy in older patients with depression in a US managed care plan. Drugs Aging 28:51–62CrossRefPubMed
35.
go back to reference Baumann M, Pommier J, Deschamps JP (1996) Medical prescription and consumption of psychotropic drugs: questions on the differences between men and women. Cah Sociol Demogr Med 36:63–78PubMed Baumann M, Pommier J, Deschamps JP (1996) Medical prescription and consumption of psychotropic drugs: questions on the differences between men and women. Cah Sociol Demogr Med 36:63–78PubMed
36.
go back to reference Van der Heyden JH, Gisle L, Hesse E, Demarest S, Drieskens S, Tafforeau J (2009) Gender differences in the use of anxiolytics and antidepressants: a population based study. Pharmacoepidemiol Drug Saf 18:1101–1110CrossRefPubMed Van der Heyden JH, Gisle L, Hesse E, Demarest S, Drieskens S, Tafforeau J (2009) Gender differences in the use of anxiolytics and antidepressants: a population based study. Pharmacoepidemiol Drug Saf 18:1101–1110CrossRefPubMed
37.
go back to reference Cruz I, Serna C, Real J, Rué M, Soler J, Galván L (2010) Comparison of the consumption of antidepressants in the immigrant and native populations in a Spanish health region: an observational study. BMC Public Health 10:255CrossRefPubMedCentralPubMed Cruz I, Serna C, Real J, Rué M, Soler J, Galván L (2010) Comparison of the consumption of antidepressants in the immigrant and native populations in a Spanish health region: an observational study. BMC Public Health 10:255CrossRefPubMedCentralPubMed
38.
go back to reference Rondet C, Cornet P, Kaoutar B, Lebas J, Chauvin P (2013) Depression prevalence and primary care among vulnerable patients at a free outpatient clinic in Paris, France, in 2010: results of a cross-sectional survey. BMC Fam Pract 14:151CrossRefPubMedCentralPubMed Rondet C, Cornet P, Kaoutar B, Lebas J, Chauvin P (2013) Depression prevalence and primary care among vulnerable patients at a free outpatient clinic in Paris, France, in 2010: results of a cross-sectional survey. BMC Fam Pract 14:151CrossRefPubMedCentralPubMed
39.
go back to reference Akincigil A, Olfson M, Siegel M, Zurlo KA, Walkup JT, Crystal S (2012) Racial and ethnic disparities in depression care in community-dwelling elderly in the United States. Am J Public Health 102(2):319–328CrossRefPubMedCentralPubMed Akincigil A, Olfson M, Siegel M, Zurlo KA, Walkup JT, Crystal S (2012) Racial and ethnic disparities in depression care in community-dwelling elderly in the United States. Am J Public Health 102(2):319–328CrossRefPubMedCentralPubMed
40.
go back to reference van Dijk L, Heerdink ER, Somai D, van Dulmen S, Sluijs EM, de Ridder DT, Griens AM, Bensing JM (2007) Patient risk profiles and practice variation in nonadherence to antidepressants, antihypertensives and oral hypoglycemics. BMC Health Serv Res 7:51CrossRefPubMedCentralPubMed van Dijk L, Heerdink ER, Somai D, van Dulmen S, Sluijs EM, de Ridder DT, Griens AM, Bensing JM (2007) Patient risk profiles and practice variation in nonadherence to antidepressants, antihypertensives and oral hypoglycemics. BMC Health Serv Res 7:51CrossRefPubMedCentralPubMed
41.
go back to reference Perez-Rodriguez MM, Baca-Garcia E, Quintero-Gutierrez FJ, Gonzalez G, Saiz-Gonzalez D, Botillo C, Basurte-Villamor I, Sevilla J, Gonzalez de Rivera JL (2006) Demand for psychiatric emergency services and immigration. Findings in a Spanish hospital during the year 2003. Eur J Public Health 16:383–387CrossRefPubMed Perez-Rodriguez MM, Baca-Garcia E, Quintero-Gutierrez FJ, Gonzalez G, Saiz-Gonzalez D, Botillo C, Basurte-Villamor I, Sevilla J, Gonzalez de Rivera JL (2006) Demand for psychiatric emergency services and immigration. Findings in a Spanish hospital during the year 2003. Eur J Public Health 16:383–387CrossRefPubMed
Metadata
Title
Trends in the dispensation of antidepressant drugs over the past decade (2000–2010) in Andalusia, Spain
Authors
M. C. González-López
C. M. Rodríguez-López
T. Parrón-Carreño
J. D. Luna
E. Del Pozo
Publication date
01-05-2015
Publisher
Springer Berlin Heidelberg
Published in
Social Psychiatry and Psychiatric Epidemiology / Issue 5/2015
Print ISSN: 0933-7954
Electronic ISSN: 1433-9285
DOI
https://doi.org/10.1007/s00127-014-0995-9

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