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Published in: Social Psychiatry and Psychiatric Epidemiology 7/2014

01-07-2014 | Review

Family functioning in first-episode psychosis: a systematic review of the literature

Authors: Katerina Koutra, Alexandros N. Vgontzas, Christos Lionis, Sofia Triliva

Published in: Social Psychiatry and Psychiatric Epidemiology | Issue 7/2014

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Abstract

Purpose

The influential role of family in the outcome of chronic schizophrenia is well documented. However, there has been relatively little research on the intrafamilial relationships of people experiencing their first episode of psychosis (FEP), a point in time when most of the changes in family dynamics are observed. The aim of this article is to present a review of the literature focusing on the family environment of FEP patients.

Methods

We carried out a computerized literature search on MEDLINE and PsycINFO (1990–2013), and a manual search of references of pertinent articles. In total, 27 studies investigating expressed emotion (EE) and family burden (FB) in FEP were identified and fulfilled the inclusion criteria.

Results

Similar to chronic patients, a high prevalence of high-EE in carers of FEP patients was reported. High-EE status appears to be independent of the patient’s illness-related characteristics, but dependent of relatives’ attributions. In contrast to chronic patients, low levels of FB and psychological distress among family members of FEP patients were observed indicating that in the early stages of the illness family involvement is not yet associated with significant disruption in their lives. Studies assessing FB in chronic patients have found a well-established link of FB with patient’s illness-related factors, but in FEP patients the families’ appraisal of FB is more closely associated with their coping mechanisms.

Conclusions

Further studies evaluating family functioning in terms of cohesion and adaptability will shed light on the intrafamilial relationships in FEP patients which may be associated with the long-term outcome of this chronic illness.
Literature
1.
go back to reference Bloch S, Szmukler GI, Herrman H, Benson A, Colussa S (1995) Counseling caregivers of relatives with schizophrenia: themes, interventions, and caveats. Fam Process 34:413–425PubMedCrossRef Bloch S, Szmukler GI, Herrman H, Benson A, Colussa S (1995) Counseling caregivers of relatives with schizophrenia: themes, interventions, and caveats. Fam Process 34:413–425PubMedCrossRef
2.
go back to reference Birchwood M, Macmillan F (1993) Early intervention in schizophrenia. Aust N Z J Psychiatry 27(3):374–378PubMedCrossRef Birchwood M, Macmillan F (1993) Early intervention in schizophrenia. Aust N Z J Psychiatry 27(3):374–378PubMedCrossRef
3.
go back to reference Addington J, Burnett P (2004) Working with families in the early stages of psychosis. In: Gleeson JFM, McGorry PD (eds) Psychological interventions in early psychosis: a treatment handbook. Wiley, Chichester, pp 99–116 Addington J, Burnett P (2004) Working with families in the early stages of psychosis. In: Gleeson JFM, McGorry PD (eds) Psychological interventions in early psychosis: a treatment handbook. Wiley, Chichester, pp 99–116
4.
go back to reference Harris A, Brennan J, Anderson J, Taylor A, Sanbrook M, Fitzgerald D, Lucas S, Redoblado-Hodge A, Gomes L, Gordon E (2005) Clinical profiles, scope and general findings of the Western Sydney first episode psychosis project. Aust N Z J Psychiatry 39(1–2):36–43PubMedCrossRef Harris A, Brennan J, Anderson J, Taylor A, Sanbrook M, Fitzgerald D, Lucas S, Redoblado-Hodge A, Gomes L, Gordon E (2005) Clinical profiles, scope and general findings of the Western Sydney first episode psychosis project. Aust N Z J Psychiatry 39(1–2):36–43PubMedCrossRef
5.
go back to reference Mackrell L, Lavender T (2004) Peer relationships in adolescents experiencing a first episode of psychosis. J Ment Health 13(5):467–479CrossRef Mackrell L, Lavender T (2004) Peer relationships in adolescents experiencing a first episode of psychosis. J Ment Health 13(5):467–479CrossRef
7.
go back to reference Wunderink A, Nienhuis FJ, Sytema S, Wiersma D (2006) Treatment delay and response rate in first episode psychosis. Acta Psychiatr Scand 113(4):332–339PubMedCrossRef Wunderink A, Nienhuis FJ, Sytema S, Wiersma D (2006) Treatment delay and response rate in first episode psychosis. Acta Psychiatr Scand 113(4):332–339PubMedCrossRef
8.
go back to reference Addington J, Van Mastrigt S, Addington D (2004) Duration of untreated psychosis: impact on 2 year outcome. Psychol Med 34(2):277–284PubMedCrossRef Addington J, Van Mastrigt S, Addington D (2004) Duration of untreated psychosis: impact on 2 year outcome. Psychol Med 34(2):277–284PubMedCrossRef
9.
go back to reference Harrigan SM, McGorry PD, Krstev H (2003) Does treatment delay in first-episode psychosis really matter? Psychol Med 33(1):97–110PubMedCrossRef Harrigan SM, McGorry PD, Krstev H (2003) Does treatment delay in first-episode psychosis really matter? Psychol Med 33(1):97–110PubMedCrossRef
10.
go back to reference Larsen TK, Moe LC, Vibe-Hansen L, Johannessen JO (2000) Premorbid functioning versus duration of untreated psychosis in 1 year outcome in first-episode psychosis. Schizophr Res 45(1–2):1–9PubMedCrossRef Larsen TK, Moe LC, Vibe-Hansen L, Johannessen JO (2000) Premorbid functioning versus duration of untreated psychosis in 1 year outcome in first-episode psychosis. Schizophr Res 45(1–2):1–9PubMedCrossRef
11.
go back to reference Robinson D, Woerner MG, Alvir JM, Bilder R, Goldman R, Geisler S, Koreen A, Sheitman B, Chakos M, Mayerhoff D, Lieberman JA (1999) Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder. Arch Gen Psychiatry 56(3):241–247PubMedCrossRef Robinson D, Woerner MG, Alvir JM, Bilder R, Goldman R, Geisler S, Koreen A, Sheitman B, Chakos M, Mayerhoff D, Lieberman JA (1999) Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder. Arch Gen Psychiatry 56(3):241–247PubMedCrossRef
12.
go back to reference Harrison G, Hopper K, Craig T, Laska E, Siegel C, Wanderling J, Dube KC, Ganev K, Giel R, an der Heiden W, Holmberg SK, Janca A, Lee PW, Leon CA, Malhotra S, Marsella AJ, Nakane Y, Sartorius N, Shen Y, Skoda C, Thara R, Tsirkin SJ, Varma VK, Walsh D, Wiersma D (2001) Recovery from psychotic illness: a 15 and 25 year international follow-up study. Br J Psychiatry 178:506–517PubMedCrossRef Harrison G, Hopper K, Craig T, Laska E, Siegel C, Wanderling J, Dube KC, Ganev K, Giel R, an der Heiden W, Holmberg SK, Janca A, Lee PW, Leon CA, Malhotra S, Marsella AJ, Nakane Y, Sartorius N, Shen Y, Skoda C, Thara R, Tsirkin SJ, Varma VK, Walsh D, Wiersma D (2001) Recovery from psychotic illness: a 15 and 25 year international follow-up study. Br J Psychiatry 178:506–517PubMedCrossRef
13.
go back to reference Addington J, Williams J, Young J, Addington D (2004) Suicidal behaviour in early psychosis. Acta Psychiatr Scand 109(2):116–120PubMedCrossRef Addington J, Williams J, Young J, Addington D (2004) Suicidal behaviour in early psychosis. Acta Psychiatr Scand 109(2):116–120PubMedCrossRef
14.
go back to reference Brown GW, Birley JL, Wing JK (1972) Influence of family life on the course of schizophrenic disorders: a replication. Br J Psychiatry 121(562):241–258PubMedCrossRef Brown GW, Birley JL, Wing JK (1972) Influence of family life on the course of schizophrenic disorders: a replication. Br J Psychiatry 121(562):241–258PubMedCrossRef
15.
go back to reference Brown GW, Monck EM, Carstairs GM, Wing JK (1962) Influence of family life on the course of schizophrenic illness. Brit J Prev Soc Med 16(2):55–68 Brown GW, Monck EM, Carstairs GM, Wing JK (1962) Influence of family life on the course of schizophrenic illness. Brit J Prev Soc Med 16(2):55–68
16.
go back to reference Leff JP, Vaughn C (1985) Expressed emotion in families: its significance for mental illness. Guildford, New York Leff JP, Vaughn C (1985) Expressed emotion in families: its significance for mental illness. Guildford, New York
17.
go back to reference Awad AG, Voruganti LN (2008) The burden of schizophrenia on caregivers: a review. Pharmacoeconomics 26(2):149–162PubMedCrossRef Awad AG, Voruganti LN (2008) The burden of schizophrenia on caregivers: a review. Pharmacoeconomics 26(2):149–162PubMedCrossRef
18.
go back to reference Wearden AJ, Tarrier N, Barrowclough C, Zastowny TR, Rahill AA (2000) A review of expressed emotion research in health care. Clin Psychol Rev 20(5):633–666PubMedCrossRef Wearden AJ, Tarrier N, Barrowclough C, Zastowny TR, Rahill AA (2000) A review of expressed emotion research in health care. Clin Psychol Rev 20(5):633–666PubMedCrossRef
19.
go back to reference Brown GW, Rutter M (1966) The measurement of family activities and relationships: a methodological study. Hum Relat 19(3):241–263CrossRef Brown GW, Rutter M (1966) The measurement of family activities and relationships: a methodological study. Hum Relat 19(3):241–263CrossRef
20.
21.
go back to reference Scazufca M, Kuipers E (1996) Links between expressed emotion and burden of care in relatives of patients with schizophrenia. Br J Psychiatry 168(5):580–587PubMedCrossRef Scazufca M, Kuipers E (1996) Links between expressed emotion and burden of care in relatives of patients with schizophrenia. Br J Psychiatry 168(5):580–587PubMedCrossRef
22.
go back to reference Vaughn CE (1989) Expressed emotion in family relationships. J Child Psychol Psychiatry 30(1):13–22PubMedCrossRef Vaughn CE (1989) Expressed emotion in family relationships. J Child Psychol Psychiatry 30(1):13–22PubMedCrossRef
23.
go back to reference Butzlaff RL, Hooley JM (1998) Expressed emotion and psychiatric relapse: a meta-analysis. Arch Gen Psychiatry 55(6):547–552PubMedCrossRef Butzlaff RL, Hooley JM (1998) Expressed emotion and psychiatric relapse: a meta-analysis. Arch Gen Psychiatry 55(6):547–552PubMedCrossRef
24.
go back to reference Cechnicki A, Bielańskab A, Hanuszkiewiczb I, Darenb A (2013) The predictive validity of expressed emotions (EE) in schizophrenia. A 20 year prospective study. J Psychiatr Res 47(2):208–214PubMedCrossRef Cechnicki A, Bielańskab A, Hanuszkiewiczb I, Darenb A (2013) The predictive validity of expressed emotions (EE) in schizophrenia. A 20 year prospective study. J Psychiatr Res 47(2):208–214PubMedCrossRef
25.
go back to reference Hooley JM (2007) Expressed emotion and relapse of psychopathology. Annu Rev Clin Psychol 3:329–352PubMedCrossRef Hooley JM (2007) Expressed emotion and relapse of psychopathology. Annu Rev Clin Psychol 3:329–352PubMedCrossRef
26.
go back to reference Biegel D, Schultz R (1999) Caregiving and caregiver interventions in aging and mental illness. Fam Relat 48:345–355 Biegel D, Schultz R (1999) Caregiving and caregiver interventions in aging and mental illness. Fam Relat 48:345–355
27.
go back to reference Schene AH (1990) Objective and subjective dimensions of family burden. Towards an integrative framework for research. Soc Psychiatry Psychiatr Epidemiol 25(6):289–297PubMedCrossRef Schene AH (1990) Objective and subjective dimensions of family burden. Towards an integrative framework for research. Soc Psychiatry Psychiatr Epidemiol 25(6):289–297PubMedCrossRef
28.
go back to reference Provencher HL, Mueser KT (1997) Positive and negative symptom behaviors and caregiver burden in the relatives of persons with schizophrenia. Schizophr Res 26(1):71–80PubMedCrossRef Provencher HL, Mueser KT (1997) Positive and negative symptom behaviors and caregiver burden in the relatives of persons with schizophrenia. Schizophr Res 26(1):71–80PubMedCrossRef
29.
go back to reference Reinhard SC (1994) Living with mental illness: effects of professional support and personal control on caregiver burden. Res Nurs Health 17(2):79–88PubMedCrossRef Reinhard SC (1994) Living with mental illness: effects of professional support and personal control on caregiver burden. Res Nurs Health 17(2):79–88PubMedCrossRef
30.
go back to reference Schene AH, Tessler RC, Gamache GM (1994) Instruments measuring family or caregiver burden in severe mental illness. Soc Psychiatry Psychiatr Epidemiol 29(5):228–240PubMedCrossRef Schene AH, Tessler RC, Gamache GM (1994) Instruments measuring family or caregiver burden in severe mental illness. Soc Psychiatry Psychiatr Epidemiol 29(5):228–240PubMedCrossRef
31.
go back to reference Szmukler G (1996) From family “burden” to caregiving. Psychiat Bull 20:449–451CrossRef Szmukler G (1996) From family “burden” to caregiving. Psychiat Bull 20:449–451CrossRef
32.
go back to reference Bulger MW, Wandersman A, Goldman CR (1993) Burdens and gratifications of caregiving: appraisal of parental care of adults with schizophrenia. Am J Orthopsychiatry 63(2):255–265PubMedCrossRef Bulger MW, Wandersman A, Goldman CR (1993) Burdens and gratifications of caregiving: appraisal of parental care of adults with schizophrenia. Am J Orthopsychiatry 63(2):255–265PubMedCrossRef
33.
go back to reference Vaddadi KS, Soosai E, Gilleard CJ, Adlard S (1997) Mental illness, physical abuse and burden of care on relatives: a study of acute psychiatric admission patients. Acta Psychiatr Scand 95(4):313–317PubMedCrossRef Vaddadi KS, Soosai E, Gilleard CJ, Adlard S (1997) Mental illness, physical abuse and burden of care on relatives: a study of acute psychiatric admission patients. Acta Psychiatr Scand 95(4):313–317PubMedCrossRef
34.
go back to reference Wittmund B, Wilms HU, Mory C, Angermeyer MC (2002) Depressive disorders in spouses of mentally ill patients. Soc Psychiatry Psychiatr Epidemiol 37(4):177–182PubMedCrossRef Wittmund B, Wilms HU, Mory C, Angermeyer MC (2002) Depressive disorders in spouses of mentally ill patients. Soc Psychiatry Psychiatr Epidemiol 37(4):177–182PubMedCrossRef
35.
go back to reference Kuipers L (1993) Family burden in schizophrenia: implications for services. Soc Psychiatry Psychiatr Epidemiol 28(5):207–210PubMed Kuipers L (1993) Family burden in schizophrenia: implications for services. Soc Psychiatry Psychiatr Epidemiol 28(5):207–210PubMed
36.
go back to reference Provencher HL (1996) Objective burden among primary caregivers of persons with chronic schizophrenia. J Psychiatr Ment Health Nurs 3(3):181–187PubMedCrossRef Provencher HL (1996) Objective burden among primary caregivers of persons with chronic schizophrenia. J Psychiatr Ment Health Nurs 3(3):181–187PubMedCrossRef
37.
go back to reference Grandon P, Jenaro C, Lemos S (2008) Primary caregivers of schizophrenia outpatients: burden and predictor variables. Psychiatry Res 158(3):335–343PubMedCrossRef Grandon P, Jenaro C, Lemos S (2008) Primary caregivers of schizophrenia outpatients: burden and predictor variables. Psychiatry Res 158(3):335–343PubMedCrossRef
38.
go back to reference Bachmann S, Bottmer C, Jacob S, Kronmuller KT, Backenstrass M, Mundt C, Renneberg B, Fiedler P, Schroder J (2002) Expressed emotion in relatives of first-episode and chronic patients with schizophrenia and major depressive disorder—a comparison. Psychiatry Res 112(3):239–250PubMedCrossRef Bachmann S, Bottmer C, Jacob S, Kronmuller KT, Backenstrass M, Mundt C, Renneberg B, Fiedler P, Schroder J (2002) Expressed emotion in relatives of first-episode and chronic patients with schizophrenia and major depressive disorder—a comparison. Psychiatry Res 112(3):239–250PubMedCrossRef
39.
go back to reference Barrelet L, Ferrero F, Szigethy L, Giddey C, Pellizzer G (1990) Expressed emotion and first-admission schizophrenia. Nine-month follow-up in a French cultural environment. Br J Psychiatry 156:357–362PubMedCrossRef Barrelet L, Ferrero F, Szigethy L, Giddey C, Pellizzer G (1990) Expressed emotion and first-admission schizophrenia. Nine-month follow-up in a French cultural environment. Br J Psychiatry 156:357–362PubMedCrossRef
40.
go back to reference Heikkila J, Ilonen T, Karlsson H, Taiminen T, Lauerma H, Leinonen KM, Wallenius E, Heinimaa M, Koponen S, Jalo P, Kaljonen A, Salokangas RK (2006) Cognitive functioning and expressed emotion among patients with first-episode severe psychiatric disorders. Compr Psychiat 47(2):152–158PubMedCrossRef Heikkila J, Ilonen T, Karlsson H, Taiminen T, Lauerma H, Leinonen KM, Wallenius E, Heinimaa M, Koponen S, Jalo P, Kaljonen A, Salokangas RK (2006) Cognitive functioning and expressed emotion among patients with first-episode severe psychiatric disorders. Compr Psychiat 47(2):152–158PubMedCrossRef
41.
go back to reference Heikkila J, Karlsson H, Taiminen T, Lauerma H, Ilonen T, Leinonen KM, Wallenius E, Virtanen H, Heinimaa M, Koponen S, Jalo P, Kaljonen A, Salakangas RK (2002) Expressed emotion is not associated with disorder severity in first-episode mental disorder. Psychiatry Res 111(2–3):155–165PubMedCrossRef Heikkila J, Karlsson H, Taiminen T, Lauerma H, Ilonen T, Leinonen KM, Wallenius E, Virtanen H, Heinimaa M, Koponen S, Jalo P, Kaljonen A, Salakangas RK (2002) Expressed emotion is not associated with disorder severity in first-episode mental disorder. Psychiatry Res 111(2–3):155–165PubMedCrossRef
42.
go back to reference Huguelet P, Favre S, Binyet S, Gonzalez C, Zabala I (1995) The use of the expressed emotion index as a predictor of outcome in first admitted schizophrenic patients in a French speaking area of Switzerland. Acta Psychiatr Scand 92(6):447–452PubMedCrossRef Huguelet P, Favre S, Binyet S, Gonzalez C, Zabala I (1995) The use of the expressed emotion index as a predictor of outcome in first admitted schizophrenic patients in a French speaking area of Switzerland. Acta Psychiatr Scand 92(6):447–452PubMedCrossRef
43.
go back to reference Lee G, Barrowclough C, Lobban F (2013) Positive affect in the family environment protects against relapse in first-episode psychosis. Soc Psychiatry Psychiatr Epidemiol. doi:10.1007/s00127-013-0768-x Lee G, Barrowclough C, Lobban F (2013) Positive affect in the family environment protects against relapse in first-episode psychosis. Soc Psychiatry Psychiatr Epidemiol. doi:10.​1007/​s00127-013-0768-x
44.
go back to reference McNab C, Haslam N, Burnett P (2007) Expressed emotion, attributions, utility beliefs, and distress in parents of young people with first episode psychosis. Psychiatry Res 151(1–2):97–106PubMedCrossRef McNab C, Haslam N, Burnett P (2007) Expressed emotion, attributions, utility beliefs, and distress in parents of young people with first episode psychosis. Psychiatry Res 151(1–2):97–106PubMedCrossRef
45.
go back to reference Meneghelli A, Alpi A, Pafumi N, Patelli G, Preti A, Cocchi A (2011) Expressed emotion in first-episode schizophrenia and in ultra high-risk patients: results from the Programma 2000 (Milan, Italy). Psychiatry Res 189(3):331–338PubMedCrossRef Meneghelli A, Alpi A, Pafumi N, Patelli G, Preti A, Cocchi A (2011) Expressed emotion in first-episode schizophrenia and in ultra high-risk patients: results from the Programma 2000 (Milan, Italy). Psychiatry Res 189(3):331–338PubMedCrossRef
46.
go back to reference Mo FYM, Chung WS, Wong SW, Chun DYY, wong KS (2008) Expressed emotion in relatives of Chinese patients with first-episode psychosis in Hong Kong. Hong Kong J Psychiatry 17(2):38–44 Mo FYM, Chung WS, Wong SW, Chun DYY, wong KS (2008) Expressed emotion in relatives of Chinese patients with first-episode psychosis in Hong Kong. Hong Kong J Psychiatry 17(2):38–44
47.
go back to reference Patterson P, Birchwood M, Cochrane R (2000) Preventing the entrenchment of high expressed emotion in first episode psychosis: early developmental attachment pathways. Aust N Z J Psychiatry 34:191–197CrossRef Patterson P, Birchwood M, Cochrane R (2000) Preventing the entrenchment of high expressed emotion in first episode psychosis: early developmental attachment pathways. Aust N Z J Psychiatry 34:191–197CrossRef
48.
go back to reference Rosenfarb I, Ventura J, Nuechterlein K, Goldstein M, Snyder KS, Hwang S (1999) Expressed emotion, appraisal and coping by patients with recent-onset schizophrenia: a pilot investigation. Cog Behav Therapy 28(1):3–8 Rosenfarb I, Ventura J, Nuechterlein K, Goldstein M, Snyder KS, Hwang S (1999) Expressed emotion, appraisal and coping by patients with recent-onset schizophrenia: a pilot investigation. Cog Behav Therapy 28(1):3–8
49.
go back to reference Stirling J, Tantam D, Thomas P, Newby D, Montague L, Ring N, Rowe S (1991) Expressed emotion and early onset schizophrenia: a 1 year follow-up. Psychol Med 21(3):675–685PubMedCrossRef Stirling J, Tantam D, Thomas P, Newby D, Montague L, Ring N, Rowe S (1991) Expressed emotion and early onset schizophrenia: a 1 year follow-up. Psychol Med 21(3):675–685PubMedCrossRef
50.
go back to reference Stirling J, Tantam D, Thomas P, Newby D, Montague L, Ring N, Rowe S (1993) Expressed emotion and schizophrenia: the ontogeny of EE during an 18 month follow-up. Psychol Med 23(3):771–778PubMedCrossRef Stirling J, Tantam D, Thomas P, Newby D, Montague L, Ring N, Rowe S (1993) Expressed emotion and schizophrenia: the ontogeny of EE during an 18 month follow-up. Psychol Med 23(3):771–778PubMedCrossRef
51.
go back to reference Addington J, Coldham EL, Jones B, Ko T, Addington D (2003) The first episode of psychosis: the experience of relatives. Acta Psychiatr Scand 108(4):285–289PubMedCrossRef Addington J, Coldham EL, Jones B, Ko T, Addington D (2003) The first episode of psychosis: the experience of relatives. Acta Psychiatr Scand 108(4):285–289PubMedCrossRef
52.
go back to reference Boydell J, Onwumere J, Dutta R, Bhavsar V, Hill N, Morgan C, Dazzan P, Morgan K, Pararajan M, Kuipers E, Jones P, Murray R, Fearon P (2013) Caregiving in first-episode psychosis: social characteristics associated with perceived ‘burden’ and associations with compulsory treatment. Early Interv Psychiatry. doi:10.1111/eip.12041 Boydell J, Onwumere J, Dutta R, Bhavsar V, Hill N, Morgan C, Dazzan P, Morgan K, Pararajan M, Kuipers E, Jones P, Murray R, Fearon P (2013) Caregiving in first-episode psychosis: social characteristics associated with perceived ‘burden’ and associations with compulsory treatment. Early Interv Psychiatry. doi:10.​1111/​eip.​12041
53.
go back to reference McCleery A, Addington J, Addington D (2007) Family assessment in early psychosis. Psychiatry Res 152(2–3):95–102PubMedCrossRef McCleery A, Addington J, Addington D (2007) Family assessment in early psychosis. Psychiatry Res 152(2–3):95–102PubMedCrossRef
54.
go back to reference Ryder A, Bean G, Dion L (2000) Caregiver responses to symptoms of first-onset psychosis: a comparative study of Chinese- and Euro-Canadian families. Transcult Psychiatry 37(2):225–236CrossRef Ryder A, Bean G, Dion L (2000) Caregiver responses to symptoms of first-onset psychosis: a comparative study of Chinese- and Euro-Canadian families. Transcult Psychiatry 37(2):225–236CrossRef
55.
go back to reference Tennakoon L, Fannon D, Doku V, O’Ceallaigh S, Soni W, Santamaria M, Kuipers E, Sharma T (2000) Experience of caregiving: relatives of people experiencing a first episode of psychosis. Br J Psychiatry 177:529–533PubMedCrossRef Tennakoon L, Fannon D, Doku V, O’Ceallaigh S, Soni W, Santamaria M, Kuipers E, Sharma T (2000) Experience of caregiving: relatives of people experiencing a first episode of psychosis. Br J Psychiatry 177:529–533PubMedCrossRef
56.
go back to reference Wolthaus JE, Dingemans PM, Schene AH, Linszen DH, Wiersma D, Van Den Bosch RJ, Cahn W, Hijman R (2002) Caregiver burden in recent-onset schizophrenia and spectrum disorders: the influence of symptoms and personality traits. J Nerv Ment Dis 190(4):241–247PubMedCrossRef Wolthaus JE, Dingemans PM, Schene AH, Linszen DH, Wiersma D, Van Den Bosch RJ, Cahn W, Hijman R (2002) Caregiver burden in recent-onset schizophrenia and spectrum disorders: the influence of symptoms and personality traits. J Nerv Ment Dis 190(4):241–247PubMedCrossRef
57.
go back to reference Wong C, Davidson L, McGlashan T, Gerson R, Malaspina D, Corcoran C (2008) Comparable family burden in families of clinical high-risk and recent-onset psychosis patients. Early Interv Psychiatry 2(4):256–261PubMedCentralPubMedCrossRef Wong C, Davidson L, McGlashan T, Gerson R, Malaspina D, Corcoran C (2008) Comparable family burden in families of clinical high-risk and recent-onset psychosis patients. Early Interv Psychiatry 2(4):256–261PubMedCentralPubMedCrossRef
58.
go back to reference Alvarez-Jimenez M, Gleeson JF, Cotton SM, Wade D, Crisp K, Yap MB, McGorry PD (2010) Differential predictors of critical comments and emotional over-involvement in first-episode psychosis. Psychol Med 40(1):63–72PubMedCrossRef Alvarez-Jimenez M, Gleeson JF, Cotton SM, Wade D, Crisp K, Yap MB, McGorry PD (2010) Differential predictors of critical comments and emotional over-involvement in first-episode psychosis. Psychol Med 40(1):63–72PubMedCrossRef
59.
go back to reference Cotton SM, Gleeson JF, Alvarez-Jimenez M, McGorry PD (2010) Quality of life in patients who have remitted from their first episode of psychosis. Schizophr Res 121(1–3):259–265PubMedCrossRef Cotton SM, Gleeson JF, Alvarez-Jimenez M, McGorry PD (2010) Quality of life in patients who have remitted from their first episode of psychosis. Schizophr Res 121(1–3):259–265PubMedCrossRef
60.
go back to reference Gonzalez-Blanch C, Martin-Munoz V, Pardo-Garcia G, Martinez-Garcia O, Alvarez-Jimenez M, Rodriguez-Sanchez JM, Vazquez-Barquero JL, Crespo-Facorro B (2010) Effects of family psychoeducation on expressed emotion and burden of care in first-episode psychosis: a prospective observational study. Span J Psychol 13(1):389–395PubMedCrossRef Gonzalez-Blanch C, Martin-Munoz V, Pardo-Garcia G, Martinez-Garcia O, Alvarez-Jimenez M, Rodriguez-Sanchez JM, Vazquez-Barquero JL, Crespo-Facorro B (2010) Effects of family psychoeducation on expressed emotion and burden of care in first-episode psychosis: a prospective observational study. Span J Psychol 13(1):389–395PubMedCrossRef
61.
go back to reference Moller-Leimkuhler AM (2005) Burden of relatives and predictors of burden. Baseline results from the Munich 5 year-follow-up study on relatives of first hospitalized patients with schizophrenia or depression. Eur Arch Psychiatry Clin Neurosci 255(4):223–231PubMedCrossRef Moller-Leimkuhler AM (2005) Burden of relatives and predictors of burden. Baseline results from the Munich 5 year-follow-up study on relatives of first hospitalized patients with schizophrenia or depression. Eur Arch Psychiatry Clin Neurosci 255(4):223–231PubMedCrossRef
62.
go back to reference Moller-Leimkuhler AM, Obermeier M (2008) Predicting caregiver burden in first admission psychiatric patients. 2 year follow-up results. Eur Arch Psychiatry Clin Neurosci 258(7):406–413PubMedCrossRef Moller-Leimkuhler AM, Obermeier M (2008) Predicting caregiver burden in first admission psychiatric patients. 2 year follow-up results. Eur Arch Psychiatry Clin Neurosci 258(7):406–413PubMedCrossRef
63.
go back to reference Patterson P, Birchwood M, Cochrane R (2005) Expressed emotion as an adaptation to loss: prospective study in first-episode psychosis. Br J Psychiatry Suppl 48:s59–s64PubMedCrossRef Patterson P, Birchwood M, Cochrane R (2005) Expressed emotion as an adaptation to loss: prospective study in first-episode psychosis. Br J Psychiatry Suppl 48:s59–s64PubMedCrossRef
64.
go back to reference Raune D, Kuipers E, Bebbington PE (2004) Expressed emotion at first-episode psychosis: investigating a carer appraisal model. Br J Psychiatry 184:321–326PubMedCrossRef Raune D, Kuipers E, Bebbington PE (2004) Expressed emotion at first-episode psychosis: investigating a carer appraisal model. Br J Psychiatry 184:321–326PubMedCrossRef
65.
go back to reference Marom S, Munitz H, Jones PB, Weizman A, Hermesh H (2005) Expressed emotion: relevance to rehospitalization in schizophrenia over 7 years. Schizophr Bull 31(3):751–758PubMedCrossRef Marom S, Munitz H, Jones PB, Weizman A, Hermesh H (2005) Expressed emotion: relevance to rehospitalization in schizophrenia over 7 years. Schizophr Bull 31(3):751–758PubMedCrossRef
66.
go back to reference Mavreas VG, Tomaras V, Karydi V, Economou M, Stefanis CN (1992) Expressed Emotion in families of chronic schizophrenics and its association with clinical measures. Soc Psychiatry Psychiatr Epidemiol 27(1):4–9PubMedCrossRef Mavreas VG, Tomaras V, Karydi V, Economou M, Stefanis CN (1992) Expressed Emotion in families of chronic schizophrenics and its association with clinical measures. Soc Psychiatry Psychiatr Epidemiol 27(1):4–9PubMedCrossRef
67.
go back to reference Kuipers E, Bebbington P, Dunn G, Fowler D, Freeman D, Watson P, Hardy A, Garety P (2006) Influence of carer expressed emotion and affect on relapse in non-affective psychosis. Br J Psychiatry 188:173–179PubMedCrossRef Kuipers E, Bebbington P, Dunn G, Fowler D, Freeman D, Watson P, Hardy A, Garety P (2006) Influence of carer expressed emotion and affect on relapse in non-affective psychosis. Br J Psychiatry 188:173–179PubMedCrossRef
68.
go back to reference Kuipers E, Onwumere J, Bebbington P (2010) Cognitive model of caregiving in psychosis. Br J Psychiatry 196(4):259–265PubMedCrossRef Kuipers E, Onwumere J, Bebbington P (2010) Cognitive model of caregiving in psychosis. Br J Psychiatry 196(4):259–265PubMedCrossRef
69.
70.
go back to reference Budd RJ, Oles G, Hughes IC (1998) The relationship between coping style and burden in the carers of relatives with schizophrenia. Acta Psychiatr Scand 98(4):304–309PubMedCrossRef Budd RJ, Oles G, Hughes IC (1998) The relationship between coping style and burden in the carers of relatives with schizophrenia. Acta Psychiatr Scand 98(4):304–309PubMedCrossRef
71.
go back to reference Lowyck B, de Hert M, Peeters E, Gilis P, Peuskens J (2001) Can we identify the factors influencing the burden on family members of patients with schizophrenia? Int J Psychiat Clin 5(2):89–96CrossRef Lowyck B, de Hert M, Peeters E, Gilis P, Peuskens J (2001) Can we identify the factors influencing the burden on family members of patients with schizophrenia? Int J Psychiat Clin 5(2):89–96CrossRef
72.
go back to reference Roick C, Heider D, Toumi M, Angermeyer M (2006) The impact of caregivers’ characteristics, patients’ conditions and regional differences on family burden in schizophrenia: a longitudinal analysis. Acta Psychiatr Scand 114(5):363–374PubMedCrossRef Roick C, Heider D, Toumi M, Angermeyer M (2006) The impact of caregivers’ characteristics, patients’ conditions and regional differences on family burden in schizophrenia: a longitudinal analysis. Acta Psychiatr Scand 114(5):363–374PubMedCrossRef
73.
go back to reference Roick C, Heider D, Bebbington P, Angermeyer M, Azorin J, Brugha T, Kilian R, Johson S, Toumi M, Kornfeld A (2007) tERG burden on caregivers of people with schizophrenia: comparison between Germany and Britain. British J Psychiat 190:333–338CrossRef Roick C, Heider D, Bebbington P, Angermeyer M, Azorin J, Brugha T, Kilian R, Johson S, Toumi M, Kornfeld A (2007) tERG burden on caregivers of people with schizophrenia: comparison between Germany and Britain. British J Psychiat 190:333–338CrossRef
74.
go back to reference Breitborde NJK, Srihari VH, Woods SW (2009) Review of the operational definition for first-episode psychosis. Early Interv Psychiatry 3:259–265PubMedCrossRef Breitborde NJK, Srihari VH, Woods SW (2009) Review of the operational definition for first-episode psychosis. Early Interv Psychiatry 3:259–265PubMedCrossRef
75.
go back to reference Pharoah F, Mari J, Rathbone J, Wong W (2010) Family intervention for schizophrenia. Cochrane Database Syst Rev 12:CD000088PubMed Pharoah F, Mari J, Rathbone J, Wong W (2010) Family intervention for schizophrenia. Cochrane Database Syst Rev 12:CD000088PubMed
76.
Metadata
Title
Family functioning in first-episode psychosis: a systematic review of the literature
Authors
Katerina Koutra
Alexandros N. Vgontzas
Christos Lionis
Sofia Triliva
Publication date
01-07-2014
Publisher
Springer Berlin Heidelberg
Published in
Social Psychiatry and Psychiatric Epidemiology / Issue 7/2014
Print ISSN: 0933-7954
Electronic ISSN: 1433-9285
DOI
https://doi.org/10.1007/s00127-013-0816-6

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