Skip to main content
Top
Published in: European Journal of Trauma and Emergency Surgery 6/2022

29-05-2021 | Distal Radius Fracture | Original Article

Complications following regional anesthesia versus general anesthesia for the treatment of distal radius fractures

Authors: Ryan Lee, Danny Lee, Pradip Ramamurti, Safa Fassihi, Jessica H. Heyer, Monica Stadecker, Michael Webber, Alice Hughes, Rajeev Pandarinath

Published in: European Journal of Trauma and Emergency Surgery | Issue 6/2022

Login to get access

Abstract

Purpose

Open reduction and internal fixation (ORIF) are commonly utilized for the repair of distal radius fractures (DRF). While general anesthesia (GA) is typically administered for ORIF, recent studies have also demonstrated promising results with the usage of regional anesthesia (RA) in the surgical treatment of distal radius fractures. This study will compare complication rates between the use of RA versus GA for ORIF of DRFs.

Methods

A multi-institutional surgical registry was utilized to identify patients who had undergone ORIF for DRFs from 2005 to 2018—these patients were stratified into GA and RA cohorts. Patients were matched utilizing coarsened-exact-matching (CEM) to compare postoperative outcomes and rates of 30-day complications were compared between the two cohorts.

Results

Upon CEM-matching, 1191 patients receiving RA were matched to 9250 patients who had received GA, with a multivariate imbalance measure (L1) statistic of < 0.001. In the matched-cohort analysis, no significant differences were observed in rates of any complication (all p ≥ 0.083). On multivariate regression analyses, RA was not associated with increased risk for any complication (p = 0.445), minor complications (p = 0.093), major complications (p = 0.758), unplanned reoperations (p = 0.355), unplanned readmissions (p = 0.799), or mortality (p = 0.579).

Conclusion

With similar safety profiles, RA is a safe and reasonable alternative to GA when managing DRFs surgically. RA may be the preferred anesthetic technique for ORIF of DRFs in patients at high risk with GA, such as those with reactions to GA in the past or with significant cardiopulmonary risk factors.
Appendix
Available only for authorised users
Literature
1.
go back to reference MacIntyre NJ, Dewan N. Epidemiology of distal radius fractures and factors predicting risk and prognosis. J Hand Ther. 2016;29(2):136–45.CrossRefPubMed MacIntyre NJ, Dewan N. Epidemiology of distal radius fractures and factors predicting risk and prognosis. J Hand Ther. 2016;29(2):136–45.CrossRefPubMed
2.
go back to reference Meena S, Sharma P, Sambharia A, et al. Fractures of distal radius: an overview. J Fam Med Prim Care. 2014;3(4):325.CrossRef Meena S, Sharma P, Sambharia A, et al. Fractures of distal radius: an overview. J Fam Med Prim Care. 2014;3(4):325.CrossRef
4.
go back to reference Porter M, Stockley I. Fractures of the distal radius: intermediate and end results in relation to radiologic parameters. Clin Orthop Relat Res. 1987;220:241–52.CrossRef Porter M, Stockley I. Fractures of the distal radius: intermediate and end results in relation to radiologic parameters. Clin Orthop Relat Res. 1987;220:241–52.CrossRef
5.
go back to reference Galos DK, Taormina DP, Crespo A, et al. Does brachial plexus blockade result in improved pain scores after distal radius fracture fixation? a randomized trial. Clin Orthop Relat Res. 2016;474(5):1255–6.CrossRef Galos DK, Taormina DP, Crespo A, et al. Does brachial plexus blockade result in improved pain scores after distal radius fracture fixation? a randomized trial. Clin Orthop Relat Res. 2016;474(5):1255–6.CrossRef
6.
go back to reference Chen HP, Shen SJ, Tsai HI, Kao SC, Yu HP. Effects of interscalene nerve block for postoperative pain management in patients after shoulder surgery. Biomed Res Int. 2015;2015:1–5. Chen HP, Shen SJ, Tsai HI, Kao SC, Yu HP. Effects of interscalene nerve block for postoperative pain management in patients after shoulder surgery. Biomed Res Int. 2015;2015:1–5.
7.
go back to reference Egol KA, Soojian MG, Walsh M, et al. Regional anesthesia improves outcome after distal radius fracture fixation over general anesthesia. J Orthop Trauma. 2012;26(9):545–9.CrossRefPubMed Egol KA, Soojian MG, Walsh M, et al. Regional anesthesia improves outcome after distal radius fracture fixation over general anesthesia. J Orthop Trauma. 2012;26(9):545–9.CrossRefPubMed
8.
go back to reference Helwani MA, Avidan MS, Ben Abdallah A, et al. Effects of regional versus general anesthesia on outcomes after total hip arthroplasty. J Bone Jt Surgery-American. 2015;97(3):186–93.CrossRef Helwani MA, Avidan MS, Ben Abdallah A, et al. Effects of regional versus general anesthesia on outcomes after total hip arthroplasty. J Bone Jt Surgery-American. 2015;97(3):186–93.CrossRef
9.
go back to reference Rundgren J, Mellstrand Navarro C, Ponzer S, et al. Regional or general anesthesia in the surgical treatment of distal radial fractures: a randomized clinical trial. J Bone Jt Surg - Am. 2019;101(13):1168–76.CrossRef Rundgren J, Mellstrand Navarro C, Ponzer S, et al. Regional or general anesthesia in the surgical treatment of distal radial fractures: a randomized clinical trial. J Bone Jt Surg - Am. 2019;101(13):1168–76.CrossRef
10.
go back to reference Sunderland S, Yarnold CH, Head SJ, et al. Regional versus general anesthesia and the incidence of unplanned health care resource utilization for postoperative pain after wrist fracture surgery: results from a retrospective quality improvement project. Reg Anesth Pain Med. 2016;41(1):22–7.CrossRefPubMed Sunderland S, Yarnold CH, Head SJ, et al. Regional versus general anesthesia and the incidence of unplanned health care resource utilization for postoperative pain after wrist fracture surgery: results from a retrospective quality improvement project. Reg Anesth Pain Med. 2016;41(1):22–7.CrossRefPubMed
11.
go back to reference O’Neil JT, Wang ML, Kim N, et al. Prospective evaluation of opioid consumption after distal radius fracture repair surgery. Am J Orthop (Belle Mead NJ). 2017;46(1):E35–40.PubMed O’Neil JT, Wang ML, Kim N, et al. Prospective evaluation of opioid consumption after distal radius fracture repair surgery. Am J Orthop (Belle Mead NJ). 2017;46(1):E35–40.PubMed
12.
go back to reference Tabrizi A, Tolouei FM, Hassani E, et al. Hematoma block versus general anesthesia in distal radius fractures in patients over 60 years in trauma emergency. Anesthesiol Pain Med. 2017;7(1):1–5. Tabrizi A, Tolouei FM, Hassani E, et al. Hematoma block versus general anesthesia in distal radius fractures in patients over 60 years in trauma emergency. Anesthesiol Pain Med. 2017;7(1):1–5.
13.
go back to reference Ottesen TD, Zogg CK, Haynes MS, et al. Dialysis patients undergoing total knee arthroplasty have significantly increased odds of perioperative adverse events independent of demographic and comorbidity factors. J Arthroplasty. 2018;33(9):2827–34.CrossRefPubMed Ottesen TD, Zogg CK, Haynes MS, et al. Dialysis patients undergoing total knee arthroplasty have significantly increased odds of perioperative adverse events independent of demographic and comorbidity factors. J Arthroplasty. 2018;33(9):2827–34.CrossRefPubMed
14.
go back to reference Wilson JM, Farley KX, Bradbury TL, et al. Is spinal anesthesia safer than general anesthesia for patients undergoing revision THA? Analysis of the ACS-NSQIP Database. Clin Orthop Relat Res. 2020;478(1):80–7.CrossRefPubMed Wilson JM, Farley KX, Bradbury TL, et al. Is spinal anesthesia safer than general anesthesia for patients undergoing revision THA? Analysis of the ACS-NSQIP Database. Clin Orthop Relat Res. 2020;478(1):80–7.CrossRefPubMed
15.
go back to reference Azin A, Hirpara D, Jackson T, et al. Emergency laparoscopic and open repair of incarcerated ventral hernias: a multi-institutional comparative analysis with coarsened exact matching. Surg Endosc. 2019;33(9):2812–20.CrossRefPubMed Azin A, Hirpara D, Jackson T, et al. Emergency laparoscopic and open repair of incarcerated ventral hernias: a multi-institutional comparative analysis with coarsened exact matching. Surg Endosc. 2019;33(9):2812–20.CrossRefPubMed
16.
go back to reference Iacus SM, King G, Porro G. Multivariate matching methods that are monotonic imbalance bounding. J Am Stat Assoc. 2011;106(493):345–61.CrossRef Iacus SM, King G, Porro G. Multivariate matching methods that are monotonic imbalance bounding. J Am Stat Assoc. 2011;106(493):345–61.CrossRef
17.
go back to reference Iacus SM, King G, Porro G. Causal inference without balance checking: coarsened exact matching. Polit Anal. 2012;20(1):1–24.CrossRef Iacus SM, King G, Porro G. Causal inference without balance checking: coarsened exact matching. Polit Anal. 2012;20(1):1–24.CrossRef
18.
go back to reference Ding DY, Mahure SA, Mollon B, et al. Comparison of general versus isolated regional anesthesia in total shoulder arthroplasty: a retrospective propensity-matched cohort analysis. J Orthop. 2017;14(4):417–24.CrossRefPubMedPubMedCentral Ding DY, Mahure SA, Mollon B, et al. Comparison of general versus isolated regional anesthesia in total shoulder arthroplasty: a retrospective propensity-matched cohort analysis. J Orthop. 2017;14(4):417–24.CrossRefPubMedPubMedCentral
19.
go back to reference Herrick MD, Liu H, Davis M, et al. Regional anesthesia decreases complications and resource utilization in shoulder arthroplasty patients. Acta Anaesthesiol Scand. 2018;62(4):540–7.CrossRefPubMed Herrick MD, Liu H, Davis M, et al. Regional anesthesia decreases complications and resource utilization in shoulder arthroplasty patients. Acta Anaesthesiol Scand. 2018;62(4):540–7.CrossRefPubMed
22.
go back to reference Lee HY, Kim SH, So KY, et al. Effects of interscalene brachial plexus block to intra-operative hemodynamics and postoperative pain for arthroscopic shoulder surgery. Korean J Anesthesiol. 2012;62(1):30–4.CrossRefPubMedPubMedCentral Lee HY, Kim SH, So KY, et al. Effects of interscalene brachial plexus block to intra-operative hemodynamics and postoperative pain for arthroscopic shoulder surgery. Korean J Anesthesiol. 2012;62(1):30–4.CrossRefPubMedPubMedCentral
23.
go back to reference Liu J, Chenjuan M, Elkassabany N, et al. Neuraxial anesthesia decreases post-operative systemic infection risk compared to general anesthesia in knee arthroplasty. Anesth Analg. 2014;117(4):1010–6.CrossRef Liu J, Chenjuan M, Elkassabany N, et al. Neuraxial anesthesia decreases post-operative systemic infection risk compared to general anesthesia in knee arthroplasty. Anesth Analg. 2014;117(4):1010–6.CrossRef
24.
go back to reference Ganta A, Ding D, Fisher N, et al. Continuous infraclavicular brachial block versus single-shot nerve block for distal radius surgery: a prospective randomized control trial. J Orthop Trauma. 2018;32(1):22–6.CrossRefPubMed Ganta A, Ding D, Fisher N, et al. Continuous infraclavicular brachial block versus single-shot nerve block for distal radius surgery: a prospective randomized control trial. J Orthop Trauma. 2018;32(1):22–6.CrossRefPubMed
25.
go back to reference Richman JM, Liu SS, Courpas G, et al. Does continuous peripheral nerve block provide superior pain control to opioids? A meta-analysis Anesth Analg. 2006;102(1):248–57.CrossRefPubMed Richman JM, Liu SS, Courpas G, et al. Does continuous peripheral nerve block provide superior pain control to opioids? A meta-analysis Anesth Analg. 2006;102(1):248–57.CrossRefPubMed
26.
go back to reference Walsh MT. Improving outcomes in ambulatory anesthesia by identifying high risk patients. Curr Opin Anaesthesiol. 2018;31(6):659–66.CrossRefPubMed Walsh MT. Improving outcomes in ambulatory anesthesia by identifying high risk patients. Curr Opin Anaesthesiol. 2018;31(6):659–66.CrossRefPubMed
28.
go back to reference Chelly JE, Greger J, Al Samsam T, et al. Reduction of operating and recovery room times and overnight hospital stays with interscalene blocks as sole anesthetic technique for rotator cuff surgery. Minerva Anestesiol. 2001;67(9):613–9.PubMed Chelly JE, Greger J, Al Samsam T, et al. Reduction of operating and recovery room times and overnight hospital stays with interscalene blocks as sole anesthetic technique for rotator cuff surgery. Minerva Anestesiol. 2001;67(9):613–9.PubMed
29.
go back to reference Mariano ER, Sandhu NS, Loland VJ, et al. A randomized comparison of infraclavicular and supraclavicular continuous peripheral nerve blocks for postoperative analgesia. Reg Anesth Pain Med. 2011;36(1):26–31.CrossRefPubMed Mariano ER, Sandhu NS, Loland VJ, et al. A randomized comparison of infraclavicular and supraclavicular continuous peripheral nerve blocks for postoperative analgesia. Reg Anesth Pain Med. 2011;36(1):26–31.CrossRefPubMed
30.
go back to reference Hadzic A, Arliss J, Yufa M, et al. A comparison of infraclavicular nerve block. Anesthesiology. 2004;1:127–32.CrossRef Hadzic A, Arliss J, Yufa M, et al. A comparison of infraclavicular nerve block. Anesthesiology. 2004;1:127–32.CrossRef
31.
go back to reference Williams B, Bottegal M, Kentor M, et al. Rebound pain scores as a function of femoral nerve block duration after anterior cruciate ligament reconstruction: retrospective analysis of a prospective, randomized clinical trial. Reg Anesth Pain Med. 2007;32(3):186–92.PubMedPubMedCentral Williams B, Bottegal M, Kentor M, et al. Rebound pain scores as a function of femoral nerve block duration after anterior cruciate ligament reconstruction: retrospective analysis of a prospective, randomized clinical trial. Reg Anesth Pain Med. 2007;32(3):186–92.PubMedPubMedCentral
32.
go back to reference Goldstein RY, Montero N, Jain SK, et al. Efficacy of popliteal block in postoperative pain control after ankle. J Orthop Trauma. 2012;26(10):557–62.CrossRefPubMed Goldstein RY, Montero N, Jain SK, et al. Efficacy of popliteal block in postoperative pain control after ankle. J Orthop Trauma. 2012;26(10):557–62.CrossRefPubMed
33.
go back to reference Yoshihara H, Yoneoka D. Understanding the statistics and limitations of large database analyses. Spine (Phila Pa 1976). 2014;39(16):1311–2.CrossRefPubMed Yoshihara H, Yoneoka D. Understanding the statistics and limitations of large database analyses. Spine (Phila Pa 1976). 2014;39(16):1311–2.CrossRefPubMed
Metadata
Title
Complications following regional anesthesia versus general anesthesia for the treatment of distal radius fractures
Authors
Ryan Lee
Danny Lee
Pradip Ramamurti
Safa Fassihi
Jessica H. Heyer
Monica Stadecker
Michael Webber
Alice Hughes
Rajeev Pandarinath
Publication date
29-05-2021
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Trauma and Emergency Surgery / Issue 6/2022
Print ISSN: 1863-9933
Electronic ISSN: 1863-9941
DOI
https://doi.org/10.1007/s00068-021-01704-1

Other articles of this Issue 6/2022

European Journal of Trauma and Emergency Surgery 6/2022 Go to the issue