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European Journal of Trauma and Emergency Surgery

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01-12-2021 | Vacuum Therapy | Original Article

Open abdomen closure methods for severe abdominal sepsis: a retrospective cohort study

Authors: Gaetano Poillucci, Mauro Podda, Giulia Russo, Sergio Gaetano Perri, Domenico Ipri, Gabriele Manetti, Maria Giulia Lolli, Renato De Angelis

Published in: European Journal of Trauma and Emergency Surgery | Issue 6/2021

Abstract

Purpose

The open abdomen (OA) procedure as part of damage control surgery represents a significant surgical advance in severe intra-abdominal infections. Major techniques used for OA are negative pressure wound therapy (NPWT) and non-NPWT. The aim of this retrospective study is to evaluate the effects of different abdominal closure methods and their outcomes in patients presenting with abdominal sepsis treated with OA.

Materials and methods

We retrospectively analyzed clinical outcomes of patients affected by severe intra-abdominal sepsis treated with OA. Demographic features, mortality prediction score, abdominal closure methods, length of hospital stay, complications and mortality rates of patients were determined and compared.

Results

This study included 106 patients, of whom 77 underwent OA with NPWT and 29 with non-NPWT. OA duration was longer in NPWT patients (p = 0.007). In-hospital mortality rates in NPWT and in non-NPWT patients were 40.3% and 51.7%, respectively (p = 0.126), with an overall 30-day mortality rate of 18.2% and 51.7%, respectively (p = 0.0002). After emergency colorectal surgery, patients who underwent OA with NPWT had a lower rate of colostomy (p = 0.025).

Conclusions

NPWT is the best temporary abdominal closure technique to decrease mortality and colostomy rates in patients managed with OA for severe intra-abdominal infections.

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Title: Open abdomen closure methods for severe abdominal sepsis: a retrospective cohort study
Authors: Gaetano Poillucci
Mauro Podda
Giulia Russo
Sergio Gaetano Perri
Domenico Ipri
Gabriele Manetti
Maria Giulia Lolli
Renato De Angelis
Publication date: 01-12-2021
Publisher: Springer Berlin Heidelberg
Keywords: Vacuum Therapy
Vacuum Therapy
Septicemia
Septicemia
Peritonitis
Vacuum Therapy
Colostomy
Abdominal Compartment Syndrome
Published in: European Journal of Trauma and Emergency Surgery / Issue 6/2021
Print ISSN: 1863-9933
Electronic ISSN: 1863-9941
DOI: https://doi.org/10.1007/s00068-020-01379-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Open abdomen closure methods for severe abdominal sepsis: a retrospective cohort study

Abstract

Purpose

Materials and methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusions

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